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Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy

Cilt: 19 Sayı: 1 21 Ocak 2025
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Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy

Öz

Mucocutaneous eruptions associated with Mycoplasma pneumoniae (MP) infection has been newly termed ‘MP-induced rash and mucositis (MIRM)’. A 17-year-old male developed a rash, bilateral purulent conjunctivitis, and oral and genital ulcers after the first dose of amoxicillin-clavulanic acid, initially considered as a drug allergy. Following hospitalization under a preliminary diagnosis of Stevens-Johnson syndrome and initiation of systemic steroids, he developed pneumonia. Laboratory tests confirmed MP infection, leading to a refined diagnosis of MIRM. The patient fully recovered within two weeks following treatment with azithromycin and intravenous immunoglobulin. This case underscores the importance of considering MIRM in the differential diagnosis of drug allergies and aims to enhance awareness of this condition.

Anahtar Kelimeler

Kaynakça

  1. Marchello C, Dale AP, Thai TN, Han DS, Ebell MH. Prevalence of Atypical Pathogens in Patients With Cough and Community-Acquired Pneumonia: A Meta-Analysis. Ann Fam Med 2016;14:552-66.
  2. Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev 2004;17:697-728.
  3. Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol 2015;72:239-45.
  4. Caubet JC, Eigenmann PA. Diagnostic issues in pediatric drug allergy. Curr Opin Allergy Clin Immunol 2012;12:341-7.
  5. Mattheij M, de Vries E. A suspicion of antibiotic allergy in children is often incorrect. J Allergy Clin Immunol 2012;129:583.
  6. Caubet JC, Kaiser L, Lemaître B, Fellay B, Gervaix A, Eigenmann PA. The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. J Allergy Clin Immunol 2011;127:218-22.
  7. Ponvert C, Perrin Y, Bados-Albiero A, Le Bourgeois M, Karila C, Delacourt C, et al. Allergy to betalactam antibiotics in children: results of a 20-year study based on clinical history, skin and challenge tests. Pediatr Allergy Immunol 2011;22:411-8.
  8. Huang PW, Chiou MH, Chien MY, Chen WW, Chu CY. Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results. J Formos Med Assoc 2022;121:1397-405.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri (Diğer)

Bölüm

Olgu Sunumu

Erken Görünüm Tarihi

20 Eylül 2024

Yayımlanma Tarihi

21 Ocak 2025

Gönderilme Tarihi

11 Haziran 2024

Kabul Tarihi

5 Ağustos 2024

Yayımlandığı Sayı

Yıl 2025 Cilt: 19 Sayı: 1

Kaynak Göster

APA
Polat, S., Ertoy Karagöl, H. İ., Koken, G., Tapisiz, A., & Bakırtaş, A. (2025). Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy. Türkiye Çocuk Hastalıkları Dergisi, 19(1), 49-52. https://doi.org/10.12956/tchd.1499268
AMA
1.Polat S, Ertoy Karagöl Hİ, Koken G, Tapisiz A, Bakırtaş A. Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy. Türkiye Çocuk Hast Derg. 2025;19(1):49-52. doi:10.12956/tchd.1499268
Chicago
Polat, Sinem, Hacer İlbilge Ertoy Karagöl, Gizem Koken, A Tapisiz, ve Arzu Bakırtaş. 2025. “Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy”. Türkiye Çocuk Hastalıkları Dergisi 19 (1): 49-52. https://doi.org/10.12956/tchd.1499268.
EndNote
Polat S, Ertoy Karagöl Hİ, Koken G, Tapisiz A, Bakırtaş A (01 Ocak 2025) Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy. Türkiye Çocuk Hastalıkları Dergisi 19 1 49–52.
IEEE
[1]S. Polat, H. İ. Ertoy Karagöl, G. Koken, A. Tapisiz, ve A. Bakırtaş, “Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy”, Türkiye Çocuk Hast Derg, c. 19, sy 1, ss. 49–52, Oca. 2025, doi: 10.12956/tchd.1499268.
ISNAD
Polat, Sinem - Ertoy Karagöl, Hacer İlbilge - Koken, Gizem - Tapisiz, A - Bakırtaş, Arzu. “Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy”. Türkiye Çocuk Hastalıkları Dergisi 19/1 (01 Ocak 2025): 49-52. https://doi.org/10.12956/tchd.1499268.
JAMA
1.Polat S, Ertoy Karagöl Hİ, Koken G, Tapisiz A, Bakırtaş A. Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy. Türkiye Çocuk Hast Derg. 2025;19:49–52.
MLA
Polat, Sinem, vd. “Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy”. Türkiye Çocuk Hastalıkları Dergisi, c. 19, sy 1, Ocak 2025, ss. 49-52, doi:10.12956/tchd.1499268.
Vancouver
1.Sinem Polat, Hacer İlbilge Ertoy Karagöl, Gizem Koken, A Tapisiz, Arzu Bakırtaş. Mycoplasma Pneumoniae Induced Rash and Mucositis (Mirm): in the Differential Diagnosis of Drug Allergy. Türkiye Çocuk Hast Derg. 01 Ocak 2025;19(1):49-52. doi:10.12956/tchd.1499268

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