BibTex RIS Kaynak Göster

Montelukast Kullanımı Sonrası İnti̇har Düşüncesi̇ ve Davranışı Gösteren Olgu

Yıl 2014, Cilt: 8 Sayı: 4, 0 - 0, 01.04.2014

Öz

Bir lökotrien reseptör antagonisti olan montelukast çocukluk çağı astım tedavisinde sıklıkla kullanılan bir ajandır. İlacın çeşitli nöropsikiyatrik yan etkileri giderek artan bir şekilde rapor edilmektedir. Bu olgu sunumunda, daha öncesinde genetik yatkınlığı ve psikolojik sorunu olmayan, montelukast kullanımı sonrası depresyon ve intihar düşüncesi/davranışı sergileyen, ilaç kesilmesi ile yakınmaları tamamen kaybolan bir olguyu rapor ediyoruz.

Kaynakça

  • Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31: 143-78.
  • Full Drug Prescribing information, MERCK & CO., INC. available at www.singulair.com/montelukast_sodium/hcp/asthma/prescribing- information.jsp accessed 17/09/10.
  • Philip G, Hustad CM, Malice MP, Noonan G, Ezekowitz A, Reiss TF, et al. Analysis of behavior-related adverse experiences in clinical trials of montelukast. J Allergy Clin Immunol 2009;124:699-706.
  • Leff JA, Busse WW, Pearlman D, Bronsky EA, Kemp J, Hendeles L, et al. Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. Engl J Med 1998;339:147-52.
  • Türkiye Çocuk Hast Derg/Turkish J Pediatr Dis / 2014; 4: 212-214
  • Wallerstedt SM, Brunlof G, Sundstrom A, Eriksson AL. Montelukast and psychiatric disorders in children. Pharmacoepidemiol Drug Saf 2009;18:858-64.
  • Philip G, Hustad C, Noonan G, Malice MP, Ezekowitz A, Reiss TF, et al. Reports of suicidality in clinical trials of montelukast. J Allergy Clin Immunol 2009;124:691-6.
  • Skillman KL, Stumpf JL. Montelukast-induced anxiety in two pediatric patients. Pharmacotherapy 2011;31:524
  • Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.

Suicide Behaviour After Montelukast Usage: A Case Report

Yıl 2014, Cilt: 8 Sayı: 4, 0 - 0, 01.04.2014

Öz

Montelukast, a leukotriene receptor antagonistis a commonly prescribed medication in management of asthma in children. It has been associated with increased risk of various neuropsychiatric events. Here, we report a young boy who presents a number of unusual neuropsychiatric events (suicide behavior) after montelukast usage. The complete resolution of the symptoms was seen upon the withdrawal of the medication

Kaynakça

  • Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31: 143-78.
  • Full Drug Prescribing information, MERCK & CO., INC. available at www.singulair.com/montelukast_sodium/hcp/asthma/prescribing- information.jsp accessed 17/09/10.
  • Philip G, Hustad CM, Malice MP, Noonan G, Ezekowitz A, Reiss TF, et al. Analysis of behavior-related adverse experiences in clinical trials of montelukast. J Allergy Clin Immunol 2009;124:699-706.
  • Leff JA, Busse WW, Pearlman D, Bronsky EA, Kemp J, Hendeles L, et al. Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. Engl J Med 1998;339:147-52.
  • Türkiye Çocuk Hast Derg/Turkish J Pediatr Dis / 2014; 4: 212-214
  • Wallerstedt SM, Brunlof G, Sundstrom A, Eriksson AL. Montelukast and psychiatric disorders in children. Pharmacoepidemiol Drug Saf 2009;18:858-64.
  • Philip G, Hustad C, Noonan G, Malice MP, Ezekowitz A, Reiss TF, et al. Reports of suicidality in clinical trials of montelukast. J Allergy Clin Immunol 2009;124:691-6.
  • Skillman KL, Stumpf JL. Montelukast-induced anxiety in two pediatric patients. Pharmacotherapy 2011;31:524
  • Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA84ZP43BJ
Bölüm Case Report
Yazarlar

Fatih Çelmeli Bu kişi benim

Gamze Çelmeli Bu kişi benim

Aslı Sürer Adanır Bu kişi benim

Doğa Türkkahraman Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2014
Gönderilme Tarihi 1 Nisan 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 8 Sayı: 4

Kaynak Göster

Vancouver Çelmeli F, Çelmeli G, Adanır AS, Türkkahraman D. Suicide Behaviour After Montelukast Usage: A Case Report. Türkiye Çocuk Hast Derg. 2014;8(4).

13548  21005     13550