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SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS

Yıl 2015, Cilt 26, Sayı 3, 0 - 0, 11.06.2016

Öz

Purpose: The aim of the study was to determine the changes in swallowing function and quality of life in early period a er radiotherapy in head and neck cancer (HNC) patients.

Methods: Fourty patients with HNC were included in the study. Swallowing function was evaluated by Modified Barium Swallowing Study. Penetration-Aspiration Scale was used to determine the penetration aspiration severity. European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and European Organization for the Research and Treatment of Cancer, Quality of Life Assessments in Head and Neck Cancer (EORTC QLQ-H&N35) which are specific to cancer patients with acceptable validity and reliability were used for quality of life assessment. All evaluations were performed three times including before radiotherapy, 1 and 3 months a er radiotherapy.

Results: The aspiration severity were gradually increased a er radiotherapy (p<0.001). There was no di erence a er radiotherapy in all subscales of EORTC QLQ-C30 (p>0.0166). Pain and fee- ling illness decreased (p<0.001), swallowing problems, dry mouth, sticky saliva (p<0.001), teeth, mouth-opening problems (p<0.016) increased a er radiotherapy. There was a moderate, negative correlation between aspiration severity and general health status scale (p<0.001). There was a moderate, positive correlation between aspiration severity and symptom scale, swallowing ability, social eating, dry mouth, sticky saliva and coughing (p<0.05).

Discussion: It can be concluded that swallowing function and swallowing related quality of life parameters were a ected negatively in the early period a er radiotherapy despite no change in general quality of life perception. It is important for clinicians to be aware of swallowing disorders and its e ects on quality of life in the early period to prevent patients from potential long-term e ects of swallowing disorders on general quality of life. 

Kaynakça

  • Gotay CC, Moore TD. Assessing quality of life in head and neck cancer. Quality Life Res. 1992;1(1):5-17.
  • Robbins KT, Storniolo AMS, Kerber C, Vicario D, Seagren S, Shea M, et al. Phase I study of highly selective supradose cisplatin infusions for advanced head and neck cancer. J Clin Oncol. 1994;12(10):2113-20.
  • The Department of Veterans A airs Laryngeal Cancer Study Group. Induction chemo-therapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal can- cer. N Engl J Med. 1991;324:1685-90.
  • Karaduman A, Serel S, Ünlüer Ö, Demir N. Penetrasyon Aspira- syon Skalası: kişiler arası güvenirlik çalışması. Fizyoter Rehabil. 2012;23(3):151-5.
  • Guzelant A, Goksel T, Ozkok S, Tasbakan S, Aysan T, Bottomley A. The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care. 2004;13(2):135-44.
  • de Grae A, de Leeuw RJ, Ros WJ, Hordijk GJ, Blijham GH, Win- nubst JA. Long term quality of life patients with head and neck cancer. Laryngoscope 2000;110(1):98-106.
  • Stringer S. Managing dysphagia in palliative care. Prof Nurs. 1999;14(7):489-92.
  • Nguyen NP, Frank C, Moltz CC, Vos P, Smith HJ, Karlsson U, et al. Impact of dysphagia on quality of life a er treatment of head- and-neck cancer. Int J Radiat Oncol Biol Phys. 2005;61(3):772-8.
  • Romesser PB, Romanyshyn JC, Schupak K, Setton J, Riaz N, Wolden SL, et al. Percutaneous endoscopic gastrostomy in oropharyngeal cancer patients treated with intensity-mod- ulated radiotherapy with concurrent chemotherapy. Cancer. 2012;118(24):6072-8.
  • Patterson JM, McColl E, Carding PN, Hildreth AJ, Kelly C, Wil- son JA. Swallowing in the rst year a er chemoradiotherapy for head and neck cancer: Clinician and patient-reported outcomes. Head Neck. 2014;36(3):352-8.
  • Eischbruch A, Lyden T, Bradford CR, Dawson LA, Haxer MJ, Miller AE, et al. Objective assessment of swallowing dysfunc- tion and aspiration a er radiation concurrent with chemo- therapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 2002;53(1):23-8.
  • Graner DE, Foote RL, Kasperbauer JL, Stoeckel RE, Okuno SH, Olsen KD, et al. Swallow function in patients before and a er intraarterial chemoradiation. Laryngoscope. 2003;113(3):573-9.
  • Smith RV, Goldman SY, Beitler JJ, Wadler SS. Decreased shortand long- term swallowing problems with altered radiotherapy dos- ing used in an organ-sparing protocol for advanced pharyngeal carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130(7):831-
  • Karp DD, Vaughn CW, Carter R, Willett B, Heeren T, Calarese P,
  • et al. Larynx preservation using induction chemotherapy plus ra- 6.
  • diation therapy as an alternative to laryngectomy in advanced
  • head and neck cancer. Am J Clin Oncol. 1991;14(4):273-9.
  • Pauloski BR. Rehabilitation of dysphagia following head and
  • neck cancer. Phys Med Rehabil Clin N Am. 2008;19(4):889-928.
  • Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, et al. Evolution of chronic dysphagia following treatment for head and
  • neck cancer. Oral Oncol. 2006;42(4):374-80.
  • Hutcheson KA, Lewin JS, Barringer D, Lisec A, Gunn GB, Moore
  • MW, et al. Late dysphagia a er radiotherapy based treatment of
  • head and neck cancer. Cancer. 2012;118(23):5793-9.
  • Nguyen NP, Frank C, Moltz CC, Vos P, Smith HJ, Bhamidipati PV, et al. Aspiration rate following chemoradiation for head and neck cancer: An underreported occurrence. Radiother Oncol.
  • ;80(3):302-6.
  • Garcia-Peris P, Paron L, Velasco C, de la Cuerda C, Camblor M,
  • Breton I, et al. Long-term prevalence of oropharyngeal dyspha- gia in head and neck cancer patients: Impact on quality of life. Clin Nutr. 2007;26(6):710-7.
  • Kotz T, Costello R, Li Y, Posner MR. Swallowing dysfunction a er chemoradiation for advanced squamous cell carcinoma of the head and neck. Head Neck 2004;26:365-72.
  • Newman LA, Vieira F, Schwiezer V, Samant S, Murry T, Woodson G, et al. Eating and weight changes following chemoradiation therapy for advanced head and neck cancer. Arch Otolaryngol Head Neck Surg. 1998;124(5):589-92.
  • Agarwal J, Dutta D, Palwe V, Gupta T, Laskar SG, Budrukkar A, et al. Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomi- tant chemo-radiation. J Cancer Res Ther. 2010;6(1):15-21.
  • Cengiz M, Ozyar E, Esassolak M, Altun M, Akmansu M, Sen M, et al. Assessment of quality of life of nasopharyngeal carcinoma patients with EORTC QLQ-C30 and H&N-35 modules. Int J Radi- ation Oncol Biol Phys. 2005;63(5):1347-53.
  • Epstein JB, Emerton S, Kolbinson DA, Le ND, Phillips N, Steven- son-Moore P, et al. Quality of life and oral function following ra- diotherapy for head and neck cancer. Head Neck. 1999;21(1):1-
  • Gillespie MB, Brodsky MB, Day TA, Lee F, Martin- Harris B. Swal- 11.
  • lowing-related quality of life a er head and neck cancer treat-
  • ment. Laryngoscope. 2004;114(8):1362-7.
  • Logemann, JA. Introduction: De nition and basic principles of
  • evaluation and treatment of swallow. In: Logemann JA, editor. Evaluation and treatment of swallowing disorders. Austin/Texas: Pro-ed; 1998. p.1-8.
  • Rosenbek JC, Robbins JA, Roecker EB, Coyle JL, Wood JL. A pene- tration-aspiration scale. Dysphagia. 1996;11(2):93-8.
  • Ackersta AH, Tan IB, Rasch C, Balm AJ, Keus RB, Schornagel JH, et al. Quality of life assessment a er supradose selective intraarterial cisplatin and concomitant radiation for inoperable stage IV head and neck squamous cell carcinoma. Arch Otolar- yngol Head Neck Surg. 2002;128(10):1185-90.

Yıl 2015, Cilt 26, Sayı 3, 0 - 0, 11.06.2016

Öz

Kaynakça

  • Gotay CC, Moore TD. Assessing quality of life in head and neck cancer. Quality Life Res. 1992;1(1):5-17.
  • Robbins KT, Storniolo AMS, Kerber C, Vicario D, Seagren S, Shea M, et al. Phase I study of highly selective supradose cisplatin infusions for advanced head and neck cancer. J Clin Oncol. 1994;12(10):2113-20.
  • The Department of Veterans A airs Laryngeal Cancer Study Group. Induction chemo-therapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal can- cer. N Engl J Med. 1991;324:1685-90.
  • Karaduman A, Serel S, Ünlüer Ö, Demir N. Penetrasyon Aspira- syon Skalası: kişiler arası güvenirlik çalışması. Fizyoter Rehabil. 2012;23(3):151-5.
  • Guzelant A, Goksel T, Ozkok S, Tasbakan S, Aysan T, Bottomley A. The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care. 2004;13(2):135-44.
  • de Grae A, de Leeuw RJ, Ros WJ, Hordijk GJ, Blijham GH, Win- nubst JA. Long term quality of life patients with head and neck cancer. Laryngoscope 2000;110(1):98-106.
  • Stringer S. Managing dysphagia in palliative care. Prof Nurs. 1999;14(7):489-92.
  • Nguyen NP, Frank C, Moltz CC, Vos P, Smith HJ, Karlsson U, et al. Impact of dysphagia on quality of life a er treatment of head- and-neck cancer. Int J Radiat Oncol Biol Phys. 2005;61(3):772-8.
  • Romesser PB, Romanyshyn JC, Schupak K, Setton J, Riaz N, Wolden SL, et al. Percutaneous endoscopic gastrostomy in oropharyngeal cancer patients treated with intensity-mod- ulated radiotherapy with concurrent chemotherapy. Cancer. 2012;118(24):6072-8.
  • Patterson JM, McColl E, Carding PN, Hildreth AJ, Kelly C, Wil- son JA. Swallowing in the rst year a er chemoradiotherapy for head and neck cancer: Clinician and patient-reported outcomes. Head Neck. 2014;36(3):352-8.
  • Eischbruch A, Lyden T, Bradford CR, Dawson LA, Haxer MJ, Miller AE, et al. Objective assessment of swallowing dysfunc- tion and aspiration a er radiation concurrent with chemo- therapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 2002;53(1):23-8.
  • Graner DE, Foote RL, Kasperbauer JL, Stoeckel RE, Okuno SH, Olsen KD, et al. Swallow function in patients before and a er intraarterial chemoradiation. Laryngoscope. 2003;113(3):573-9.
  • Smith RV, Goldman SY, Beitler JJ, Wadler SS. Decreased shortand long- term swallowing problems with altered radiotherapy dos- ing used in an organ-sparing protocol for advanced pharyngeal carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130(7):831-
  • Karp DD, Vaughn CW, Carter R, Willett B, Heeren T, Calarese P,
  • et al. Larynx preservation using induction chemotherapy plus ra- 6.
  • diation therapy as an alternative to laryngectomy in advanced
  • head and neck cancer. Am J Clin Oncol. 1991;14(4):273-9.
  • Pauloski BR. Rehabilitation of dysphagia following head and
  • neck cancer. Phys Med Rehabil Clin N Am. 2008;19(4):889-928.
  • Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, et al. Evolution of chronic dysphagia following treatment for head and
  • neck cancer. Oral Oncol. 2006;42(4):374-80.
  • Hutcheson KA, Lewin JS, Barringer D, Lisec A, Gunn GB, Moore
  • MW, et al. Late dysphagia a er radiotherapy based treatment of
  • head and neck cancer. Cancer. 2012;118(23):5793-9.
  • Nguyen NP, Frank C, Moltz CC, Vos P, Smith HJ, Bhamidipati PV, et al. Aspiration rate following chemoradiation for head and neck cancer: An underreported occurrence. Radiother Oncol.
  • ;80(3):302-6.
  • Garcia-Peris P, Paron L, Velasco C, de la Cuerda C, Camblor M,
  • Breton I, et al. Long-term prevalence of oropharyngeal dyspha- gia in head and neck cancer patients: Impact on quality of life. Clin Nutr. 2007;26(6):710-7.
  • Kotz T, Costello R, Li Y, Posner MR. Swallowing dysfunction a er chemoradiation for advanced squamous cell carcinoma of the head and neck. Head Neck 2004;26:365-72.
  • Newman LA, Vieira F, Schwiezer V, Samant S, Murry T, Woodson G, et al. Eating and weight changes following chemoradiation therapy for advanced head and neck cancer. Arch Otolaryngol Head Neck Surg. 1998;124(5):589-92.
  • Agarwal J, Dutta D, Palwe V, Gupta T, Laskar SG, Budrukkar A, et al. Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomi- tant chemo-radiation. J Cancer Res Ther. 2010;6(1):15-21.
  • Cengiz M, Ozyar E, Esassolak M, Altun M, Akmansu M, Sen M, et al. Assessment of quality of life of nasopharyngeal carcinoma patients with EORTC QLQ-C30 and H&N-35 modules. Int J Radi- ation Oncol Biol Phys. 2005;63(5):1347-53.
  • Epstein JB, Emerton S, Kolbinson DA, Le ND, Phillips N, Steven- son-Moore P, et al. Quality of life and oral function following ra- diotherapy for head and neck cancer. Head Neck. 1999;21(1):1-
  • Gillespie MB, Brodsky MB, Day TA, Lee F, Martin- Harris B. Swal- 11.
  • lowing-related quality of life a er head and neck cancer treat-
  • ment. Laryngoscope. 2004;114(8):1362-7.
  • Logemann, JA. Introduction: De nition and basic principles of
  • evaluation and treatment of swallow. In: Logemann JA, editor. Evaluation and treatment of swallowing disorders. Austin/Texas: Pro-ed; 1998. p.1-8.
  • Rosenbek JC, Robbins JA, Roecker EB, Coyle JL, Wood JL. A pene- tration-aspiration scale. Dysphagia. 1996;11(2):93-8.
  • Ackersta AH, Tan IB, Rasch C, Balm AJ, Keus RB, Schornagel JH, et al. Quality of life assessment a er supradose selective intraarterial cisplatin and concomitant radiation for inoperable stage IV head and neck squamous cell carcinoma. Arch Otolar- yngol Head Neck Surg. 2002;128(10):1185-90.

Ayrıntılar

Bölüm Makaleler
Yazarlar

Selen Serel Aslan>

0000-0002-2463-7503

Yayımlanma Tarihi 11 Haziran 2016
Yayınlandığı Sayı Yıl 2015, Cilt 26, Sayı 3

Kaynak Göster

Bibtex @ { tfrd486429, journal = {Fizyoterapi Rehabilitasyon}, issn = {1300-8757}, eissn = {2148-0109}, address = {}, publisher = {Türkiye Fizyoterapistler Derneği}, year = {2016}, volume = {26}, number = {3}, pages = {0 - 0}, title = {SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS}, key = {cite}, author = {Serel Aslan, Selen} }
APA Serel Aslan, S. (2016). SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS . Fizyoterapi Rehabilitasyon , 26 (3) , 0-0 . Retrieved from https://dergipark.org.tr/tr/pub/tfrd/issue/40541/486429
MLA Serel Aslan, S. "SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS" . Fizyoterapi Rehabilitasyon 26 (2016 ): 0-0 <https://dergipark.org.tr/tr/pub/tfrd/issue/40541/486429>
Chicago Serel Aslan, S. "SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS". Fizyoterapi Rehabilitasyon 26 (2016 ): 0-0
RIS TY - JOUR T1 - SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS AU - SelenSerel Aslan Y1 - 2016 PY - 2016 N1 - DO - T2 - Fizyoterapi Rehabilitasyon JF - Journal JO - JOR SP - 0 EP - 0 VL - 26 IS - 3 SN - 1300-8757-2148-0109 M3 - UR - Y2 - 2022 ER -
EndNote %0 Fizyoterapi Rehabilitasyon SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS %A Selen Serel Aslan %T SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS %D 2016 %J Fizyoterapi Rehabilitasyon %P 1300-8757-2148-0109 %V 26 %N 3 %R %U
ISNAD Serel Aslan, Selen . "SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS". Fizyoterapi Rehabilitasyon 26 / 3 (Haziran 2016): 0-0 .
AMA Serel Aslan S. SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS. Fizyoterapi Rehabilitasyon. 2016; 26(3): 0-0.
Vancouver Serel Aslan S. SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS. Fizyoterapi Rehabilitasyon. 2016; 26(3): 0-0.
IEEE S. Serel Aslan , "SWALLOWING AND QUALITY OF LIFE OUTCOMES EARLY AFTER RADIATION THERAPY IN HEAD AND NECK CANCER PATIENTS", Fizyoterapi Rehabilitasyon, c. 26, sayı. 3, ss. 0-0, Haz. 2016