Maternal sigara maruziyeti çocukluk döneminde obezojenik etkili midir?

Year 2019, Volume: 17 Issue: 2, 217 - 220, 31.08.2019

Gülşen Göney

Abstract

Çocukluk
çağı obezitesi önemli bir halk sağlığı problemidir. Sigaraya aktif ya da pasif
maruziyet toksik kimyasallara maruziyetin en önemli yollarından birisidir. 2006
yılında toksik kimyasallara maruziyet yoluyla obezitenin ortaya çıkabildiği
fikri ve obezojen terimi öne sürülmüştür. Son yıllarda maternal sigara
maruziyeti ile çocukluk çağında aşırı kiloluluk ve obezite görülme sıklığı
arasındaki ilişkiyi anlamaya yönelik birçok çalışma yapılmıştır. Sunulan yorumda
maternal sigara maruziyetinin çocukluk çağında olası obezojenik etkisi
değerlendirilmiştir.

Keywords

Halk sağlığı , obezojenler , obezite , sigara

Does maternal smoke exposure has an obesogenic effect of childhood?

Abstract

Childhood obesity is
a worldwide public health concern. Active or passive exposure to tobacco smoke is also a
significant source of toxic
chemicals exposure. In 2006 years the idea and the term of obesogen was
put forward that some of chemical substances make an obesity. Recent years remarkable number of studies
investigate that relationship between maternal smoking exposure and prevalance of childhood overweight or
obesity. In this commentary is evaluated that possible obesogenic effects of maternal smoking exposure
in the childhood period.

Keywords

public health , obesity , obesogens , Smoking

References

• 1. Grün F, Blumberg B. Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis. Rev Endocr Metab Disord 2007;8:161-71.
• 2. WHO. 2018 Available from: http://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight [last accessed 05 May 2018].
• 3. Behl M, Rao D, Aagaard K, Davidson TL, Levin ED, Slotkin TA, Srinivasan S, Wallinga D, White MF, Walker VR, Thayer KA. Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review. EHP 2013;121:170.
• 4. Grun F, Blumberg B. Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinol 2006;147:50-55.
• 5. Wenger D, Gerecke AC, Heeb NV, Schmid P, Hueglin C, Naegeli H, Zenobi R. In vitro estrogenicity of ambient particulate matter: contribution of hydroxylated polycyclic aromatic hydrocarbons. J Appl Toxicol 2009;29:223-32.
• 6. Gao YJ, Holloway AC, Zeng ZH, Lim GE, Petrik JJ, Foster WG, Lee RM. Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function. Obes Res 2005;13:687-92.
• 7. Kieser JA, Groeneveld HT, Da Silva PC. Dental asymmetry, maternal obesity, and smoking. Am J Phys Anthropol 1997;102:133-9.
• 8. Oken E, Levitan EB, Gillman MW. Maternal smoking during pregnancy and child overweight: systematic review and meta-analysis. Int J Obes 2008;32:201-10.
• 9. Al Mamun A, Lawlor DA, Alati R, O'callaghan MJ, Williams GM, Najman JM. Does maternal smoking during pregnancy have a direct effect on future offspring obesity? Evidence from a prospective birth cohort study. Am J Epidemiol 2006;164:317-25.
• 10. Toschke A, Koletzko B, Slikker W, Hermann M, von Kries R. Childhood obesity is associated with maternal smoking in pregnancy. Eur J Pediatr 2002;161:445-8.