Squamous cell carcinoma at the tongue of a cat

Abstract

Squamous cell carcinomas are malign tumors composed of squamous epithelium of skin and mucous membranes and showing squamous differentiation. These tumors constitute 60-70% of malignant tumors in the cats. Environmental factors that predispose to the development of oral squamous cell carcinoma in cats are defined as exposure to cigarette smoke, the use of flea collar, and nutrition with tuna fish-containing ingredients. A male, 11-year-old Chinchilla race cat was brought to Ankara University, Veterinary Faculty, Veterinary Hospital, Department of Internal Diseases with complaints of anorexia, weakness, dysphagia, fatigue and difficulty in swallowing solid food. At the physical examination, it was determined that the tongue was deviated to the left side and kept in the same position continuously, and the right side of the tongue was thickened. At general anesthesia, a biopsy was taken from the bulk at the root of the tongue with fine needle biopsy. The diagnosis of squamous cell carcinoma was confirmed.

Keywords

• carsinoma,cat

References

1. 1. Beam SL, Rassnick KM, Moore AS, McDonough SP. An immunohistochemical study of cyclooxygenase-2 expression in various feline neoplasms. Veterinary Pathology 2003; 40:496-500.
2. 2. Bertone ER, Snyder LA, Moore AS. Environmental and Lifestyle Risk Factors for Oral Squamous Cell Carcinoma in Domestic Cats. Journal of Veterinary Internal Medicine 2003; 17, 557-562.
3. 3. Erer H . Veteriner Onkoloji 2000; 3.
4. 4. Fox LE, Rosenthal RC, King RR, Levine PB, Vail DM, Helfand SC, MacEwen EG, Perez-Soler R, Calderwood-Mays M, Kurzman ID. Use of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum (II), a liposomal cisplatin analogue, in cats with oral squamous cell carcinoma. American Journal of Veterinary Research 2000; 61, 791-795.
5. 5. Gendler A, Lewis JR, Reetz JA, Schwarz T. Computed tomographic features of oral squamous cell carcinoma in cats: 18 cases (2002-2008). Journal of the American Veterinary Medical Association 2010; 236, 319-325.
6. 6. Hayes A, Scase T, Miller J, Murphy S, Sparkes A, Adams V. COX-1 and COX-2 Expression in Feline Oral Squamous Cell Carcinoma. Journal of Comparative Pathology 2006; 135, 93-99.
7. 7. Hayes AM, Adams VJ, Scase TJ, Murphy S. Survival of 54 cats with oral squamous cell carcinoma in United Kingdom general practice: Paper. Journal of Small Animal Practice 2007; 48, 394-399.
8. 8. Hutson CA, Willauer CC, Walder EJ, Stone JL, Klein MK. Treatment of mandibular squamous cell carcinoma in cats by use of mandibulectomy and radiotherapy: seven cases (1987-1989). Journal of the American Veterinary Medical Association 1992; 201, 777-781.

9. 9. Jubb KVF KP, Palmer N. Pathology of Domestic Animals. 1991; Vol 1, 339-367.
10. 10. Leibman NF, Larson VF, Ogilvie GK Oral squamous cell carcinoma in cats. Handbook of Small Animal Gastroenterology 2003; 380-382.
11. 11. Snyder LA, Bertone ER, Jakowski RM, Dooner MS, Jennings-Ritchie J, Moore AS. p53 expression and environmental tobacco smoke exposure in feline oral squamous cell carcinoma. Veterinary Pathology 2004; 41, 209-214.
12. 12. Stebbins KE, Morse CC, Goldschmidt MH Feline Oral Neoplasia: A Ten-Year Survey. Veterinary Pathology 1989; 26, 121-128.
13. 13. Takeuchi K, Ito F. EGF receptor in relation to tumor development: Molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors. FEBS Journal 2010; 277, 316-326.
14. 14. Thrall DE, LaRue SM. Palliative radiation therapy. Seminars in veterinary medicine and surgery (small animal) 1995; 10, 205-208.
15. 15.Tiwari M. Primary intraosseous carcinoma of the mandible: A case report with literature review. Journal of Oral and Maxillofacial Pathology 2011; 15, 205-210.