Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy

Engin Uğur Yardımcı; Melda Apaydın; Fazıl Gelal; Fatih Dağ; Ali Özmezoğlu; Ali Fırat Sarp

Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy

Abstract

Objectives: This study aims to evaluate volumetric and morphological changes following CyberKnife radiotherapy of vestibular schwannomas. Patients and Methods: Between March 2011 and December 2013, a total of 39 patients 15 males, 24 females; mean age 52 years; range, 19 to 86 years who underwent CyberKnife hypofractionated radiotherapy were retrospectively analyzed. Tumor volume calculations were done by manual segmentation. Tumor morphology was classified by arbitrary cystic scaling. Local tumor control, tumor progression, transient swelling rates, and changes in tumor morphology were evaluated. Results: Local tumor control and transient swelling rates were 87% and 46%, respectively. Cystic tumors responded better than solid tumors to treatment as evidenced by volume reduction rates 87% vs. 58% , although local control rates were not significantly different 93% vs. 83% . Transient swelling rates were significantly higher in cystic tumors than in solid tumors 67% vs. 29% . Post-treatment volume changes were not correlated with gender, age group, or pre-procedural tumor volume. Conclusion: CyberKnife radiotherapy is an effective way of achieving local tumor control in patients with vestibular schwannomas. Although higher rates of volumetric regression would be expected in more cystic tumors than more solid tumors, local control rates are similar.

Keywords

CyberKnife, hypofractionated stereotactic radiotherapy, vestibular schwannoma

References

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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Engin Uğur Yardımcı This is me

Melda Apaydın This is me

Fazıl Gelal This is me

Fatih Dağ This is me

Ali Özmezoğlu This is me

Ali Fırat Sarp This is me

Publication Date

June 3, 2019

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2019 Volume: 29 Number: 2

IZ

https://izlik.org/JA32MT52ZJ

Cite

RIS / Bibtex

APA

Yardımcı, E. U., Apaydın, M., Gelal, F., Dağ, F., Özmezoğlu, A., & Sarp, A. F. (2019). Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. The Turkish Journal of Ear Nose and Throat, 29(2), 61-66. https://izlik.org/JA32MT52ZJ

AMA

1.Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT. 2019;29(2):61-66. https://izlik.org/JA32MT52ZJ

Chicago

Yardımcı, Engin Uğur, Melda Apaydın, Fazıl Gelal, Fatih Dağ, Ali Özmezoğlu, and Ali Fırat Sarp. 2019. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat 29 (2): 61-66. https://izlik.org/JA32MT52ZJ.

EndNote

Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF (June 1, 2019) Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. The Turkish Journal of Ear Nose and Throat 29 2 61–66.

IEEE

[1]E. U. Yardımcı, M. Apaydın, F. Gelal, F. Dağ, A. Özmezoğlu, and A. F. Sarp, “Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy”, Tr-ENT, vol. 29, no. 2, pp. 61–66, June 2019, [Online]. Available: https://izlik.org/JA32MT52ZJ

ISNAD

Yardımcı, Engin Uğur - Apaydın, Melda - Gelal, Fazıl - Dağ, Fatih - Özmezoğlu, Ali - Sarp, Ali Fırat. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat 29/2 (June 1, 2019): 61-66. https://izlik.org/JA32MT52ZJ.

JAMA

1.Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT. 2019;29:61–66.

MLA

Yardımcı, Engin Uğur, et al. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat, vol. 29, no. 2, June 2019, pp. 61-66, https://izlik.org/JA32MT52ZJ.

Vancouver

1.Engin Uğur Yardımcı, Melda Apaydın, Fazıl Gelal, Fatih Dağ, Ali Özmezoğlu, Ali Fırat Sarp. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT [Internet]. 2019 Jun. 1;29(2):61-6. Available from: https://izlik.org/JA32MT52ZJ