Cadmium Toxicity in Rainbow Trout (Oncorhynchus Mykiss): A Study on Heart and Muscle Tissue

Year 2020, Volume: 7 Issue: 4, 983 - 987, 20.10.2020

Mehmet Reşit Taysı , Muammer Kırıcı , Mahinur Kırıcı , Bünyamin Sögüt , Mehmet Akif Bozdayı , Seyithan Taysı

https://doi.org/10.30910/turkjans.802746

Abstract

Keywords

Cadmium toxicity, oxidative, peroxynitrite, muscle, heart

Gökkuşağı Alabalıklarında (Oncorhynchus Mykiss) Kadmiyum Toksisitesi: Kalp ve Kas Üzerine Bir Araştırma

Abstract

Bu çalışma, gökkuşağı alabalığının (Oncorhynchus mykiss) kas ve kalp dokularındaki ölümcül olmayan kadmiyum konsantrasyonlarına (1, 3 ve 5 mg / L) maruz kalmadan (24, 48 ve 96 saat) kaynaklanan oksidatif stres tepkilerini belirlemeyi ve karşılaştırmayı amaçlamaktadır. Malondialdehit (MDA) ve Peroksinitrit (ONOOˉ) parametreleri sırasıyla oksidatif / nitrosatif stresi belirlemek için çalışıldı. Kalp ve kas dokularının MDA ve ONOO− değerleri, hem saatler hem de dozlar açısından birbirleri arasında istatistiksel olarak anlamlı (P <0.05) farklılıklar gösterdi. Kontrol ve diğer gruplar arasında kas dokusu ONOO− ve MDA değerlerindeki fark istatistiksel olarak anlamlı bulundu (P <0.05). Kontrol grubu ile diğer gruplar arasında benzer şekilde kalp dokusu ONOO− ve MDA değerlerinde de fark istatistiksel olarak anlamlı bulundu (P <0.05). Her iki parametre için de uygulanan doz miktarı arttıkça, elde edilen ONOO− ve MDA değerlerinin ortalaması önemli ölçüde artmıştır. Sonuç olarak kadmiyumun kalp ve kas dokularında ONOO− ve MDA düzeylerini artırdığı, strese neden olduğu ve küçük dozlarda bile balıklar için toksik olduğu tespit edildi.

Keywords

oksidatif, peroksinitrit, kas, kalp

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