Amaç: Radikal nefrektomi yapılan hastalarda yaş ve cinsiyetin sağ kalıma etkisini araştırmak. Gereç ve Yöntemler: 1990 – 2012 tarihleri arasında kliniğimizde böbrek tümörü nedeniyle radikal nefrektomi operasyonu uygulanan 177 hasta retrospektif olarak değerlendirildi. Hastalar yaş gruplarına göre 5 gruba
Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81.
Lindblad P. Epidemiology of renal cell carcinoma. Scand J Surg 2004;93:88-96.
Ferlay J, Bray F, Forman D, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and MortalityWorldwide: IARC Cancer- Base No. 10 2010, International Agency for Research on Cancer:Lyon,France.
Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg classification of renal cell tumours. J Pathol 1997;183:131- 3.
Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176:2353-8.
Bergstrom A, Hsieh CC, Lindblad P, et al. Obesity and renal cell cancer-a quantitative review. Br J Cancer 2001;85:984- 90.
Pischon T, Lahmann PH, Boeing H, et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition EPIC. Int J Cancer 2006;118:728-38
Weikert S, Boeing H, Pischon T, et al. Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition. Am J Epidemiol 2008;167:438-46.
Waalkes S, Merseburger AS, Kramer MW, et al. Obesity is associated with improved survival in patients with organ- confined clear-cell kidney cancer. Cancer Causes Control 2010;21:1905-10.
Clague J, Lin J, Cassidy A, et al. Family history and risk of renal cell carcinoma: results from a case control study and systematic meta-analysis. Cancer Epidemiol Biomarkers Prev 2009;18:801-7.
Gudbjartsson T, Jónasdóttir T.J, Thoroddsen A, et al. A population-based familial aggregation analysis indicates genetic contribution in a majority of renal cell carcinomas. Int J Cancer 2002;100:476-9.
Patard JJ, Rodriguez A, Rioux-Leclercq N, et al. Prognos- tic significance of the mode of detection in renal tumours. BJU Int 2002;90:358-63.
Kato M, Suzuki T, Suzuki Y, et al. Natural history of small renal cell carcinoma: evaluation of growth rate, histological grade, cell proliferation and apoptosis. J Urol 2004;172:863-6.
Tsui KH, Shvarts O, Smith RB, et al. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urol 2000;163:426-30.
Jung EJ, Lee HJ, Kwak C,et al. Young age is independent prognostic factor for cancer-specific survival of low-stage clear cell renal cell carcinoma. Urology 2009;73:137-41.
Denzinger S, Otto W, Burger M,et al. Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?. World J Urol 2013;31:1073-80.
Lee L.S, Yuen J.S.P, Sim H.G. Renal cell carcinoma in yo- ung patients is associated with poorer prognosis. Annals Academy of Medicine 2011;40:401-406.
Thompson R.H, Ordonez M.A, Iasones A, et al. Renal cell carsinoma in young and old patient-is there a difference? Urologe A 2008;47:1182-1186.
Karakiewicz P.T, Jeldres C, Suardi N, et al. Age at diag- nosis is determinant factor of renal cell carcinoma-spe- sific survival in patients treatedwith nephrectomy. J urol 2008;180:1262-1266.
Sangchul J, Hwang G.J, Cheol K. et al. Gender-specific clinicopathological features and survival in patients with renal cell carcinoma RCC. BJU int 2011;110:28-33.
Edward N. R, Tobias K, Geoffrey B. et al. The effect of gen- der and age on kidney cancer survival: Younger age is an indipendent prognostic factor in women with renal cell carcinoma. Urologic Oncology 2013;1-5.
Schrader A.J, Sevinç S, Olbert P.J.et al. Gender specific cha- racteristics and survival of renal cell carcinoma. Urologe 2008;47:1182-1186.
Onishi T, Oishi H, Goto H.et al. Gender as a prognostic factor in patients with renal cell carcinoma. BJU int 2002; 90:32-36.
Aron M, Nguyen M.M, Stein R.J, et.al. Impact of gender in renal cell carcinoma: an analysis of the SEER database. Eur Urol jul 2008;54:13340.
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The effect of age and gender on survival in renal cell carcinoma
Year 2015,
Volume: 10 Issue: 1, 6 - 11, 01.01.2015
Objective: To evaluate the effect of age and gender on survival in patients who underwent radical nephrectomy. Materials and Methods: A hundred and seventy seven patients who underwent radical retrospectively because of renal carcinoma were eveluated retrosepectively between 1990 and 2012. Patients are divided into five groups
Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81.
Lindblad P. Epidemiology of renal cell carcinoma. Scand J Surg 2004;93:88-96.
Ferlay J, Bray F, Forman D, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and MortalityWorldwide: IARC Cancer- Base No. 10 2010, International Agency for Research on Cancer:Lyon,France.
Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg classification of renal cell tumours. J Pathol 1997;183:131- 3.
Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176:2353-8.
Bergstrom A, Hsieh CC, Lindblad P, et al. Obesity and renal cell cancer-a quantitative review. Br J Cancer 2001;85:984- 90.
Pischon T, Lahmann PH, Boeing H, et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition EPIC. Int J Cancer 2006;118:728-38
Weikert S, Boeing H, Pischon T, et al. Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition. Am J Epidemiol 2008;167:438-46.
Waalkes S, Merseburger AS, Kramer MW, et al. Obesity is associated with improved survival in patients with organ- confined clear-cell kidney cancer. Cancer Causes Control 2010;21:1905-10.
Clague J, Lin J, Cassidy A, et al. Family history and risk of renal cell carcinoma: results from a case control study and systematic meta-analysis. Cancer Epidemiol Biomarkers Prev 2009;18:801-7.
Gudbjartsson T, Jónasdóttir T.J, Thoroddsen A, et al. A population-based familial aggregation analysis indicates genetic contribution in a majority of renal cell carcinomas. Int J Cancer 2002;100:476-9.
Patard JJ, Rodriguez A, Rioux-Leclercq N, et al. Prognos- tic significance of the mode of detection in renal tumours. BJU Int 2002;90:358-63.
Kato M, Suzuki T, Suzuki Y, et al. Natural history of small renal cell carcinoma: evaluation of growth rate, histological grade, cell proliferation and apoptosis. J Urol 2004;172:863-6.
Tsui KH, Shvarts O, Smith RB, et al. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urol 2000;163:426-30.
Jung EJ, Lee HJ, Kwak C,et al. Young age is independent prognostic factor for cancer-specific survival of low-stage clear cell renal cell carcinoma. Urology 2009;73:137-41.
Denzinger S, Otto W, Burger M,et al. Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?. World J Urol 2013;31:1073-80.
Lee L.S, Yuen J.S.P, Sim H.G. Renal cell carcinoma in yo- ung patients is associated with poorer prognosis. Annals Academy of Medicine 2011;40:401-406.
Thompson R.H, Ordonez M.A, Iasones A, et al. Renal cell carsinoma in young and old patient-is there a difference? Urologe A 2008;47:1182-1186.
Karakiewicz P.T, Jeldres C, Suardi N, et al. Age at diag- nosis is determinant factor of renal cell carcinoma-spe- sific survival in patients treatedwith nephrectomy. J urol 2008;180:1262-1266.
Sangchul J, Hwang G.J, Cheol K. et al. Gender-specific clinicopathological features and survival in patients with renal cell carcinoma RCC. BJU int 2011;110:28-33.
Edward N. R, Tobias K, Geoffrey B. et al. The effect of gen- der and age on kidney cancer survival: Younger age is an indipendent prognostic factor in women with renal cell carcinoma. Urologic Oncology 2013;1-5.
Schrader A.J, Sevinç S, Olbert P.J.et al. Gender specific cha- racteristics and survival of renal cell carcinoma. Urologe 2008;47:1182-1186.
Onishi T, Oishi H, Goto H.et al. Gender as a prognostic factor in patients with renal cell carcinoma. BJU int 2002; 90:32-36.
Aron M, Nguyen M.M, Stein R.J, et.al. Impact of gender in renal cell carcinoma: an analysis of the SEER database. Eur Urol jul 2008;54:13340.