Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition

Winda Shari; Dina Erliana; Khusnul Azizah; Charles Banon; Avidlyandi Avidlyandi; Khafit Wiradimafan; Salprima Yudha S.; Morina Adfa

doi:10.29133/yyutbd.1601765

Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition

Abstract

The purpose of this study is to assess the antibacterial activity of pyroligneous acid derived from Cinnamomum porrectum (Roxb.) Kosterm stem wood and three types of its constituent chemicals against Staphylococcus aureus. The antibacterial activity of pyroligneous acid produced from C. porrectum was determined using the well diffusion method. The test concentrations varied from 1.56% to 100%, with the lowest to highest concentrations being 1.56%, 3.12%, 6.25%, 12.5%, 25%, 50% vv-1, and 100%. The pure components that make up the pyroligneous acid were also examined at two concentrations: 1.56% and 3.12% vv-1 or mv-1. The negative control was sterile distilled water, while the positive control was clindamycin 0.025% mv-1. Pyroligneous acid's ability to suppress S. aureus ATCC 6538 growth rose as the concentration tested, having MIC and MBC values of 0.39% and 0.78% vv-1, respectively. The principal constituents of C. porrectum pyroligneous acid, 2,6-dimethoxyphenol, 2-hydroxyphenol, and acetic acid, could inhibit S. aureus at a concentration of 1.56% by 12.55; 9.10; 8.33 mm and 16.36; 12.62; 11.48 mm at a concentration of 3.12%, respectively. This pyroligneous acid's potential to suppress the growth of S. aureus has been shown since it comprises acetic acid and phenol derivatives with antibacterial capabilities.

Keywords

Supporting Institution

DRPM-DIKTI The ministry of education, culture, research, and technology, Republic of Indonesia

Project Number

Contract number 3952/UN30.15/PT/2024

Ethical Statement

Ethical approval is not required for this study

Thanks

The author would like to thank DRPM-DIKTI for supporting this research with the penelitian tesis magister scheme, contract number 3952/UN30.15/PT/2024.

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Details

Primary Language

English

Subjects

Agricultural Biotechnology (Other)

Journal Section

Research Article

Authors

Winda Shari This is me
0009-0003-9034-7488
Indonesia

Dina Erliana This is me
0009-0008-8842-257X
Indonesia

Khusnul Azizah This is me
0009-0007-3759-9853
Indonesia

Charles Banon This is me
0000-0002-5795-2227
Indonesia

Avidlyandi Avidlyandi This is me
0000-0003-0387-040X
Indonesia

Khafit Wiradimafan This is me
0009-0003-4941-1134
Indonesia

Salprima Yudha S. This is me
0000-0002-3095-5284
Indonesia

Morina Adfa ^*
0000-0002-7944-3992
Indonesia

Early Pub Date

September 30, 2025

Publication Date

September 30, 2025

Submission Date

December 15, 2024

Acceptance Date

May 21, 2025

Published in Issue

Year 2025 Volume: 35 Number: 3

DOI

https://doi.org/10.29133/yyutbd.1601765

IZ

https://izlik.org/JA52CA92JM

Cite

RIS / Bibtex

APA

Shari, W., Erliana, D., Azizah, K., Banon, C., Avidlyandi, A., Wiradimafan, K., Yudha S., S., & Adfa, M. (2025). Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition. Yuzuncu Yıl University Journal of Agricultural Sciences, 35(3), 392-402. https://doi.org/10.29133/yyutbd.1601765

AMA

1.Shari W, Erliana D, Azizah K, et al. Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition. YYU J AGR SCI. 2025;35(3):392-402. doi:10.29133/yyutbd.1601765

Chicago

Shari, Winda, Dina Erliana, Khusnul Azizah, et al. 2025. “Effectiveness of Cinnamomum Porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus Aureus Growth Inhibition”. Yuzuncu Yıl University Journal of Agricultural Sciences 35 (3): 392-402. https://doi.org/10.29133/yyutbd.1601765.

EndNote

Shari W, Erliana D, Azizah K, Banon C, Avidlyandi A, Wiradimafan K, Yudha S. S, Adfa M (September 1, 2025) Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition. Yuzuncu Yıl University Journal of Agricultural Sciences 35 3 392–402.

IEEE

[1]W. Shari et al., “Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition”, YYU J AGR SCI, vol. 35, no. 3, pp. 392–402, Sept. 2025, doi: 10.29133/yyutbd.1601765.

ISNAD

Shari, Winda - Erliana, Dina - Azizah, Khusnul - Banon, Charles - Avidlyandi, Avidlyandi - Wiradimafan, Khafit - Yudha S., Salprima - Adfa, Morina. “Effectiveness of Cinnamomum Porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus Aureus Growth Inhibition”. Yuzuncu Yıl University Journal of Agricultural Sciences 35/3 (September 1, 2025): 392-402. https://doi.org/10.29133/yyutbd.1601765.

JAMA

1.Shari W, Erliana D, Azizah K, Banon C, Avidlyandi A, Wiradimafan K, Yudha S. S, Adfa M. Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition. YYU J AGR SCI. 2025;35:392–402.

MLA

Shari, Winda, et al. “Effectiveness of Cinnamomum Porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus Aureus Growth Inhibition”. Yuzuncu Yıl University Journal of Agricultural Sciences, vol. 35, no. 3, Sept. 2025, pp. 392-0, doi:10.29133/yyutbd.1601765.

Vancouver

1.Winda Shari, Dina Erliana, Khusnul Azizah, Charles Banon, Avidlyandi Avidlyandi, Khafit Wiradimafan, Salprima Yudha S., Morina Adfa. Effectiveness of Cinnamomum porrectum Roxb. Kosterm Pyroligneous Acid and Its Compounds in Staphylococcus aureus Growth Inhibition. YYU J AGR SCI. 2025 Sep. 1;35(3):392-40. doi:10.29133/yyutbd.1601765

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