Determination of Phytochemicals, Antimicrobial, Antioxidant and Allelopathic Effects of Fagonia cretica L., collected from Jamshoro, Pakistan

Yıl 2022, Cilt: 32 Sayı: 4, 785 - 794, 30.12.2022

Qamar-u-nisa Tunio , Muhammad Rafiq , Azhar Ali Tunio , Abdul Sattar Qureshi , Tanzeel Rehman , Mihr Ali Bhutto , Zubeda Lasharı

https://doi.org/10.29133/yyutbd.1122798

Cited By: 1

Öz

Medicinal plant Fagonia cretica L., is well known in traditional medicines for curing various complaints of human beings from ancient times and is locally known as Dhamasa. Previous many studies have reported the presence of many phytochemicals, antimicrobial, and antioxidant properties in the various parts of this plant. Therefore, here in this study, we have presented a comprehensive study on the presence of similar medicinal and chemical properties of Dhamsa found in Jamshoro District, Pakistan. For this study, extracts of the root, stem, leaf, and pod of the plant were prepared separately from three different solvents, water, ethanol, and methanol. Then the amount and presence of various phytochemicals, antimicrobial, antioxidant properties, and allelopathic effects were determined in all the extracts. The obtained results of this study confirm the presence of medicinal important phytochemicals in the plant extracts. The antimicrobial testing of this plant proved its highest activity against E. coli (16 ±1.4mm), Salmonella typhi (18±0.7mm), and Pseudomonas aeruginosa (15±1.4mm) in methanol, water, and ethanol extracts respectively. The presence of antioxidant activities was also observed in the ethanolic extract of the leaf at about 0.98 mg/ml. While this plant showed allelopathic effects on the growth of radish and spinach plants. So, we have concluded this study that Fagonia cretica L., collected from Jamshoro has the same or more important properties compared to the same plant from other regions, which proves the similar significant value of the Fagonia cretica plant of Jamshoro in various fields of medicinal sciences.

Anahtar Kelimeler

Fagonia cretica, phytochemicals, allelopathy, antimicrobial, antioxidant

Kaynakça

• Akhtar, N., & Begum, S. (2009). Ethnopharmacological Important Plants of Jalala, District Mardan, Pakistan. Pakistan Journal of Plant Sciences, 15(2).
• Bajaj, S. P., Rapaport, S. I., & Prodanos, C. (1981). A Simplified Procedure for Purification of Human Prothrombin, Factor IX and Factor X. Preparative Biochemistry, 11(4), 397–412. https://doi.org/10.1080/00327488108065531
• Baquar, S. R. (1989). Medicinal and poisonous plants of Pakistan. Medicinal and Poisonous Plants of Pakistan.
• Charan, T. R., Bhutto, M. A., Bhutto, M. A., Tunio, A. A., Khuhro, G. M., Khaskheli, S. A., & Mughal, A. A. (2021). “Nanomaterials of curcumin-hyaluronic acid”: their various methods of formulations, clinical and therapeutic applications, present gap, and future directions. Future Journal of Pharmaceutical Sciences, 7(1), 126. https://doi.org/10.1186/s43094-021-00281-9
• Djeridane, A., Yousfi, M., Nadjemi, B., Maamri, S., Djireb, F., & Stocker, P. (2008). Phenolic extracts from various Algerian plants as strong inhibitors of porcine liver carboxylesterase. Http://Dx.Doi.Org/10.1080/14756360600810399, 21(6), 719–726. https://doi.org/10.1080/14756360600810399
• Edeoga, H. O., Okwu, D. E., & Mbaebie, B. O. (2005). Phytochemical constituents of some Nigerian medicinal plants. African Journal of Biotechnology, 4(7), 685–688.
• Gökmeşe, F., Uslu, I., & Aytimur, A. (2013). Preparation and Characterization of PVA/PVP Nanofibers as Promising Materials for Wound Dressing. Http://Dx.Doi.Org/10.1080/03602559.2013.814144, 52(12), 1259–1265. https://doi.org/10.1080/03602559.2013.814144
• HUSSAIN, A., ZIA, M., & MIRZA, B. (2007). Materials and Methods. Turkish Journal of Biology, 31(1), 19–24.
• Institute of Plant Sciences – University of Sindh Jamshoro. (n.d.). Retrieved April 27, 2022, from https://usindh.edu.pk/academics/faculties-uos/natural-sciences/institute-of-plant-sciences/
• Khan, M. M., Qureshi, A. M., Murtaza, R., & Munazir, S. (2020). Preliminary Phytochemical Screening, Proximate Analysis, Antioxidant and Antibacterial Activities of an Algal Species of Hydrodictyon Reticulatum. Journal of Bioresource Management, 7(4). https://doi.org/10.35691/JBM.0202.0147
• Khan Marwat, S., Ajab Khan, M., Ahmad, M., & Zafar, M. (2008). ETHNOPHYTOMEDICINES FOR TREATMENT OF VARIOUS DIEASES IN D. I. KHAN DISTRICT. In Sarhad J. Agric (Vol. 24, Issue 2).
• Kumaran, A., & Joel Karunakaran, R. (2007). In vitro antioxidant activities of methanol extracts of five Phyllanthus species from India. LWT - Food Science and Technology, 40(2), 344–352. https://doi.org/10.1016/j.lwt.2005.09.011
• Mangrio, A. M., Rafiq, M., Naqvi, S. H. A., Junejo, S. A., Mangrio, S. M., & Rind, N. A. (2016). EVALUATION OF PHYTOCHEMICAL CONSTITUENTS AND ANTIBACTERIAL POTENTIAL OF AVICENNIA MARINA AND RHIZOPHORA MUCRONATA. Pakistan Journal of Biotechnology, 13(4), 259–265. https://pjbt.org/index.php/pjbt/article/view/119
• Prasad, S., Kashyap, R. S., Deopujari, J. Y., Purohit, H. J., Taori, G. M., & Daginawala, H. F. (2007). Effect of Fagonia Arabica (Dhamasa) on in vitro thrombolysis. BMC Complementary and Alternative Medicine, 7. https://doi.org/10.1186/1472-6882-7-36
• Rahu, M. I., Naqvi, S. H. A., Memon, N. H., Idrees, M., Kandhro, F., Pathan, N. L., Sarker, M. N. I., & Aqeel Bhutto, M. (2021). Determination of antimicrobial and phytochemical compounds of Jatropha curcas plant. Saudi Journal of Biological Sciences, 28(5), 2867–2876. https://doi.org/10.1016/J.SJBS.2021.02.019
• Rawal, A., Muddeshwar, M., & Biswas, S. (2004). Effect of Rubia cordifolia, Fagonia cretica linn, and Tinospora cordifolia on free radical generation and lipid peroxidation during oxygen-glucose deprivation in rat hippocampal slices. Biochemical and Biophysical Research Communications, 324(2), 588–596. https://doi.org/10.1016/j.bbrc.2004.09.094
• Sajid B. (n.d.). Phytochemical screening and antimicrobial activity of Fagonia cretica plant extracts against selected microbes. Soni, A., & Sosa, S. (2013). Phytochemical Analysis and Free Radical Scavenging Potential of Herbal and Medicinal Plant Extracts. ~ 22 ~ Journal of Pharmacognosy and Phytochemistry, 2(4), 22–29.
• Tamilselvi, N., Krishnamoorthy, P., Dhamotharan, R., Arumugam, P., & Sagadevan, E. (2012). Analysis of total phenols,total tannins and screening of phytocomponents in Indigofera aspalathoides (Shivanar Vembu) Vahl EX DC. Available Online Www.Jocpr.Com Journal of Chemical and Pharmaceutical Research, 2012(6), 3259–3262.
• Turk, M. A., & Tawaha, A. M. (2003). Allelopathic effect of black mustard (Brassica nigra L.) on germination and growth of wild oat (Avena fatua L.). Crop Protection, 22(4), 673–677. https://doi.org/10.1016/S0261-2194(02)00241-7
• Vaghasiya, Y., Dave, R., & Chanda, S. (2011). Phytochemical analysis of some medicinal plants from western region of India. Research Journal of Medicinal Plant, 5(5), 567–576. https://doi.org/10.3923/RJMP.2011.567.576
• Wazir, S., Saima, S., Dasti, A., Plant, M. S.-P. J. of, & 2007, undefined. (n.d.). Ethnobotanical importance of salt range species of district Karak, Pakistan. Agris.Fao.Org.