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Review of Arnebia euсhroma as a Potential Medicinal Plant Based on Phytochemistry and Pharmacological Activity

Yıl 2024, Cilt: 34 Sayı: 1, 176 - 191, 31.03.2024
https://doi.org/10.29133/yyutbd.1306035

Öz

Abstract: Arnebia euchroma, commonly known as "Pink Arnebia," is a plant from the Boraginaceae family found in Western and Central Asia. Traditionally, it has been used to treat respiratory, gastrointestinal, and dermatological ailments. Recent studies have highlighted its pharmacological properties and potential health advantages, resulting in increased interest in this plant. Pharmacognostic investigations have revealed the presence of various beneficial phytochemicals. Phytochemical studies have identified several bioactive compounds in A. euсhroma, such as eugormoside A, eugormoside B, scopoletin, and β-sitosterol, which exhibit diverse biological activities like antioxidant, antimicrobial, anticancer, and anti-ulcer effects. The therapeutic potential of these bioactive compounds suggests that A. euсhroma could be beneficial for a wide range of diseases. Pharmacological studies have validated the plant's healing properties, demonstrating its antimicrobial activity against various pathogens. Furthermore, A. euсhroma extracts possess antioxidant and anti-inflammatory properties that can potentially mitigate oxidative stress and inflammation-related diseases. Other pharmacological actions of A. euсhroma include wound healing, gastroprotective, hepatoprotective, and anti-diabetic effects. Overall, A. euсhroma exhibits promise as a medicinal plant with significant health benefits. However, further research is required to identify the active compounds responsible for its pharmacological activity and elucidate their primary mechanisms of action. Additionally, clinical studies are necessary to assess its safety and efficacy when used therapeutically. The primary objective of this review is to showcase the phytochemical composition and traditional ethnopharmacological applications of A. euchroma worldwide. The study examines previous research concerning this plant, laying the foundation for a forward-looking perspective on the potential future of A. euchroma.

Kaynakça

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Yıl 2024, Cilt: 34 Sayı: 1, 176 - 191, 31.03.2024
https://doi.org/10.29133/yyutbd.1306035

Öz

Kaynakça

  • Akram, M. (2019). Ethnopharmacological survey of medicinal plants used in traditional medicine by the communities of Alai Valley, Kyrgyzstan. Journal of Ethnopharmacology, 235, 84-99.
  • Aldayarov, N., Tulobaev, A., Salykov, R., Jumabekova, J., Kydyralieva, B., Omurzakova, N., Kurmanbekova, G., Imanberdieva, N., Usubaliev, B., Borkoev, B., Salieva, K., Salieva, Z., Omurzakov, T., & Chekirov, K. (2022). An ethnoveterinary study of wild medicinal plants used by the Kyrgyz farmers. Journal of Ethnopharmacology, 285, 114842. https://doi.org/10.1016/j.jep.2021.114842
  • Ashkani-Esfahani, S., Imanieh, M., Khoshneviszadeh, M., Meshksar, A., Noorafshan, A., Geramizadeh, B., Ebrahimi, S., Handjani, F., & Tanideh, N. (2012). The healing effect of Arnebia euchroma in second degree burn wounds in rat as an animal model. Iranian Red Crescent Medical Journal, 14(2), 70-74.
  • Ali, N. (2007). Anti-inflammatory and analgesic potential of A. euсhroma (Royle) Johnst. Roots. Journal of Ethnopharmacology, 113(3), 406-411.
  • Amanpour, A., Vandamme, J., Polat, S., Kelebek, H., Van, D. J., & Serkan, S. (2015). GC–MS–olfactometric characterization of the most aroma-active components in a representative aromatic extract from Iranian saffron (Crocus sativus L.). Food Chemistry, 182, 251–256.
  • Andújar, I, Recio, M C, Bacelli, T, Giner, R M, & Ríos, J L (2010). Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus. British Journal of Pharmacology, 160(2), 376-88.
  • Annan, K., & Houghton, P. J. (2008). Antibacterial, antioxidant, and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. And Gossypium arboreum L, wound-healing plants of Ghana. Journal of Ethnopharmacology, 119(1), 141-144.
  • Baktybekov, E. (2017). Natural Dyeing with Plant Materials in Kyrgyzstan. Textile Research Journal, 87(17), 2049-2057.
  • Bali, Y. Y., Yilanci, S., Yuzbasioglu, M., Unlu, R. E., Orhan, E., Guvenalp, Z. (2015). The evaluation of wound healing potential of acetyl alkannin isolated from Arnebia purpurea. Planta Medica, 81(16), 14.
  • Bazarbayev, Z. (2020). Traditional Natural Dyeing of Wool with A. euсhroma in Kyrgyzstan. Textiles and Light Industrial Science and Technology, 2(1), 26-33.
  • Cao, H., Zhang, W., Liu, D., Hou, M., Liu, S., He, W., Lin, J., & Shao, M. (2020). Identification, in vitro evaluation and modeling studies of the constituents from the roots of Arnebia euchroma for antitumor activity and STAT3 inhibition. Bioorganic Chemistry, 96, 103655. https://doi.org/10.1016/j.bioorg.2020.103655
  • Choudhary, M. I., Yousaf, S., & Ahmed, S. (2004). Nautaquinone A: a cytotoxic and antimicrobial naphthoquinone derivative from Arnebia euchroma. Planta Medica, 70(12), 1150-1152.
  • Dar, G. H., Bhagat, R. C., & Khan, M. A. (2002). Biodiversity of the Kashmir Himalaya. Valley Book.
  • El-Keblawy, A. A., & Khedr, A. H. A. (2017). Population structure and ecological role of Moringa peregrina (Forssk.) Fiori. at its northwestern range edge in the Hajar Mountains. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, 151(1), 29–38. https://doi.org/10.1080/11263504.2015.1056856
  • Fabricant, D. S., & Farnsworth, N. R. (2001). The value of plants used in traditional medicine for drug discovery. Environmental Health Perspectives, 109, 69-75.
  • Ganie, S. A., Jan, A., Muzaffar, S., Zargar, B. A., Hamid, R., & Zargar, M. A. (2012). Radical scavenging and antibacterial activity of Arnebia benthamii methanol extract. Asian Pacific Journal of Tropical Medicine, 5(10), 766–772. https://doi.org/10.1016/S1995-7645(12)60140-0
  • Gao, H., Liu, L., Qu, Z. Y., Wei, F. X., Wang, S. Q., Chen, G. (2011). Anti-adenovirus activities of shikonin, a component of Chinese herbal medicine in vitro. Biological & Pharmaceutical Bulletin, 34(2), 197-202.
  • Gupta, K., Garg, S., Singh, J., & Kumar, M. (2014). Enhanced production of naphthoquinone metabolite (shikonin) from cell suspension culture of Arnebia sp. and it’s up-scaling through bioreactor. 3 Biotech, 4(3), 263–273. https://doi.org/10.1007/s13205-013-0149-x
  • Hosseini, A., Mirzaee, F., Davoodi, A., Jouybari, H. B., & Azadbakht, M. (2018). The traditional medicine aspects, biological activity and phytochemistry of Arnebia spp. Medical Glasnik, 15(1). https://doi.org/10.17392/926-18
  • Huang, G., Zhao, H. R., Meng, Q. Q., Zhang, Q. J., Dong, J. Y., Zhu, B. Q. (2018). Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents. European Journal of Medicinal Chemistry, 143(1), 166-81.
  • Husain, A., Ahmad, I., & Khan, M. S. (2001). Anti-inflammatory, anti-ulcer and hepatoprotective activities of Arnebia euchroma. Journal of Ethnopharmacology, 75(2-3), 283-289.
  • Hussain, H., Krohn, K., & Ahmad, V. U. (2012). Naphthoquinone derivatives from A. euchroma with antibacterial and antifungal activities. Pharmaceutical Biology, 50(4), 489-493.
  • Hussain, S., Imran, M., Nadeem, M. (2019). Phytochemicals from various tissues of A. euсhroma and their bioactivities. Molecules, 24(7), 1315.
  • Israili, Z. H. (2009). Ethnopharmacological studies of indigenous medicinal plants of Sarban Hills, Abbottabad District, Pakistan. Journal of Ethnopharmacology, 122(2), 142-157.
  • Jain, S. C., Singh, B., & Jain, R. (2000). Arnebins and antimicrobial activities of Arnebia hispidissima DC. Cell cultures. Phytomedicine, 6(6), 474-476. https://doi.org/10.1016/S0944-7113(00)80077-X
  • Janibekov, A. A. (2017). Medicinal plants of the Kyrgyzstan flora: ethnopharmacological aspects. Journal of Applied Pharmaceutical Science, 7(3), 196-201.
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  • Liu, X. (2019). Shikonin exerts anti-psoriatic effects by inhibiting the proliferation and differentiation of keratinocytes. Life Sciences, 219, 274-284.
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  • Monsef-Esfahani, H. R., Amini, M., & Abdollahi, M. (2004). Antinociceptive effects of A. euсhroma root extract. Journal of Ethnopharmacology, 91(2-3), 301-304.
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  • Parray, J. A., Hamid, R., Kamili, A. N., Shameem, N., Jan, S., & Ganai, B. A. (2015). Biological efficacy and radical scavenging potential of shikonin in Arnebia benthamii (Wall ex. G Don) Johnston. Industrial Crops and Products, 74, 434–439. https://doi.org/10.1016/j.indcrop.2015.04.040
  • Pirbalouti, A., Azizi, S., Koohpayeh, A., & Golparvar, A. (2002). An overview of the ethnobotany and socio-economic importance of medicinal plants in Kyrgyzstan. Journal of Applied Pharmaceutical Science, 4(4), 030-039.
  • Roeder, E., & Rengel-Mayer, B. (1993). Pyrrolizidine alkaloids from Arnebia euchroma. Planta Medica, 59, 192-192.
  • Rustaiyan, A., Larijani, K., Yazdani, D., & Nadji, K. (2001). Chemical constituents of A. euchroma (Royle) Johnston roots. Daru, 9(3), 14-16.
  • Saeedi, M., Ebrahimzadeh, M. A., Nabavi, S. F., & Nabavi, S. M. (2001). Antioxidant activity of methanol extract of Arnebia euchroma. Pharmacognosy Magazine, 7(28), 46-51.
  • Samant, S. S., & Lal, M. (2015). Diversity, distribution, ecological niche modeling and economic importance of Bamboo species in North Western and Western Himalaya. International Journal of Biodiversity Science and Management, 3(2007), 234–251.
  • Sankawa, U., Ebizuka, Y., Miyazaki, T., Isomura, Y., Otsuka, H., Shibata, S., & Fukukoa, F. (1977). Antitumor activity of shikonin and its derivatives. Chem. Pharm. Bull., 25(9), 2392-5.
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  • Sharma, P. (2020). Arnebin-7 isolated from A. euсhroma root accelerates diabetic wound healing in vitro and in vivo. Journal of Ethnopharmacology, 257, 112868.
  • Shen, C. C., Syu, W. J., Li, S. Y., Lin, C. H., Lee, G. H., & Sun, C. M. (2002). Antimicrobial activities of naphthazarins from A. euсhroma. Journal of Natural Products, 65(12), 1857-862.
  • Shilov, S. V., Gulbaram, O., Lashyn, N., Ilya, S., Korotetskiy, N. V., Kudashkina, N. V., Zubenko, R. A., Parenova, A. B., Jumagaziyeva, Z. A., & Iskakbayeva, S. T. (2022). Component Composition and Biological Activity of Various Extracts of Onosma gmelinii (Boraginaceae). International Journal of Biomaterials, 2022(10), 1-14.
  • Singh, B. (2001). Scope of Arid Zone Plants as Medicinal Agents. Doctoral Dissertation. Ph. D. Thesis. University of Rajasthan, Jaipur, India.
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Toplam 84 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Bitki Bilimi
Bölüm Makaleler
Yazarlar

Urmat Kazybekov 0009-0006-4651-0534

Gülbübü Kurmanbekova 0000-0002-4340-0886

Fatih Törnük 0000-0002-7313-0207

Erken Görünüm Tarihi 25 Mart 2024
Yayımlanma Tarihi 31 Mart 2024
Kabul Tarihi 22 Aralık 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 34 Sayı: 1

Kaynak Göster

APA Kazybekov, U., Kurmanbekova, G., & Törnük, F. (2024). Review of Arnebia euсhroma as a Potential Medicinal Plant Based on Phytochemistry and Pharmacological Activity. Yuzuncu Yıl University Journal of Agricultural Sciences, 34(1), 176-191. https://doi.org/10.29133/yyutbd.1306035

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