SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’

Nurdan Filik

doi:10.55549/zbs.1483208

EN

SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’

Abstract

The Quorum Sensing System (QS) an interbacterial communication system, which causes disease by triggering virulence, is now accepted and proven. The most important of this cellular communication network are signaling molecules. The general name of the signaling molecule mentioned here is Quorum Sensing Molecules (QSMs); specifically, the most famous molecule is N-Acyl Homoserine Lactones (AHLs). This sophisticated mode of cell-to-cell signalling, known as QS, was first discovered in marin bacteria as Vibrio fischeri. While investigating many research questions, V. fischeri was studied and sampled as a QS model organism. However, awareness of communication in this bacteria has raised the question of whether other tiny creatures in the microorganism world use QS system. Recent studies have proven that yeast and molds also communicate with each other using QS system. Molds and yeast, which are mycological organisms, use QS system, but the details are not yet known. In this manuscript, we review the information available to date on these processes in yeast and mold. We disscussed the diverse chemical ‘languages’ used by yeast and mold, their possible cross-talk and interkingdom interactions with other organisms. Cosmopalitan Candida albicans is a common cause of mucosal infections. In certain groups of immunocompromised patients it also causes life-threatening bloodstream infections that are disseminated to internal organs. It is a polymorphic fungus, being able to grow in yeast, hyphal and pseudohyphal forms. The hyphal form penetrates epithelia and endothelia, causing tissue damage and allowing access to the bloodstream. We discuss the role of QS in fungal colonisation pathogenesis. This review describes of the network of signal transduction pathways that monitors environmental cues to activate a programme of hypha-specific gene transcription, and the molecular processes that drive the highly polarized growth of hyphae.

Keywords

Yeast and mold, Quorum sensing system (QS), N-Acyl Homoserine Lacton (AHLs), Quorum sensing molecules (QSMs), Candida albicans, Fungal diseases

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Details

Primary Language

English

Subjects

Microbiology (Other)

Journal Section

Review

Authors

Nurdan Filik ^*
0000-0003-4376-7298
Türkiye

Publication Date

August 1, 2024

Submission Date

May 13, 2024

Acceptance Date

May 14, 2024

Published in Issue

Year 2024 Volume: 5 Number: 3

DOI

https://doi.org/10.55549/zbs.1483208

IZ

https://izlik.org/JA57GC73WC

APA

Filik, N. (2024). SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’. Zeugma Biological Science, 5(3), 10-21. https://doi.org/10.55549/zbs.1483208

AMA

1.Filik N. SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’. zbs. 2024;5(3):10-21. doi:10.55549/zbs.1483208

Chicago

Filik, Nurdan. 2024. “SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’”. Zeugma Biological Science 5 (3): 10-21. https://doi.org/10.55549/zbs.1483208.

EndNote

Filik N (August 1, 2024) SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’. Zeugma Biological Science 5 3 10–21.

IEEE

[1]N. Filik, “SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’”, zbs, vol. 5, no. 3, pp. 10–21, Aug. 2024, doi: 10.55549/zbs.1483208.

ISNAD

Filik, Nurdan. “SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’”. Zeugma Biological Science 5/3 (August 1, 2024): 10-21. https://doi.org/10.55549/zbs.1483208.

JAMA

1.Filik N. SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’. zbs. 2024;5:10–21.

MLA

Filik, Nurdan. “SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’”. Zeugma Biological Science, vol. 5, no. 3, Aug. 2024, pp. 10-21, doi:10.55549/zbs.1483208.

Vancouver

1.Nurdan Filik. SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’. zbs. 2024 Aug. 1;5(3):10-21. doi:10.55549/zbs.1483208

Abstract

SECRET TINY TALK COMMENTARY OF FUNGI: YEAST AND MOLD AS FORZANDO CANDIDIASIS DISEASE ‘CANDIDA ALBICANS’

Abstract

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