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Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery

Yıl 2016, Cilt: 16 Sayı: 1, 68 - 75, 30.04.2015

Fulya Taktak

https://doi.org/10.5578/fmbd.26306
Cited By: 4

Öz

In this study, poly(2‐dimethylamino)ethyl methacrylate (PDMAEMA)    gels were prepared via in situ
polymerization reaction. Synthesized hydrogel was characterized with FTIR spectroscopy and SEM. The
pH‐ and temperature dependentswelling / deswelling behavior was investigated. The hydrogelshowed
highest value of swelling at pH 2. The rising temperature led to a decrease in swelling ratio due to the
fact that hydrophobic interactions between polymer segments become dominant. Furthermore, it was
observed that PDMAEMA hydrogel exhibited rapid deswelling rate in response to temperature and pH.
The drug release profile of PDMAEMA hydrogel has been reported by using Ibuprofen as a model drug.

Anahtar Kelimeler

Hydrogel Controlled drug delivery Rapid response Deswelling

Toplam 0 adet kaynakça vardır.

Ayrıntılar

Konular Mühendislik
Bölüm Makaleler
Yazarlar

Fulya Taktak

Yayımlanma Tarihi 30 Nisan 2015
Gönderilme Tarihi 18 Mart 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 16 Sayı: 1

Kaynak Göster

APA Taktak, F. (2015). Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 16(1), 68-75. https://doi.org/10.5578/fmbd.26306
AMA Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. Nisan 2015;16(1):68-75. doi:10.5578/fmbd.26306
Chicago Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16, sy. 1 (Nisan 2015): 68-75. https://doi.org/10.5578/fmbd.26306.
EndNote Taktak F (01 Nisan 2015) Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16 1 68–75.
IEEE F. Taktak, “Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery”, Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, c. 16, sy. 1, ss. 68–75, 2015, doi: 10.5578/fmbd.26306.
ISNAD Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16/1 (Nisan 2015), 68-75. https://doi.org/10.5578/fmbd.26306.
JAMA Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16:68–75.
MLA Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, c. 16, sy. 1, 2015, ss. 68-75, doi:10.5578/fmbd.26306.
Vancouver Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16(1):68-75.

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International Journal of Polymeric Materials and Polymeric Biomaterials
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Prediction of the deswelling behaviors of pH- and temperature-responsive poly(NIPAAm-co-AAc) IPN hydrogel by artificial intelligence techniques
Research on Chemical Intermediates
https://doi.org/10.1007/s11164-019-03957-3
Injectable amphiphilic hydrogel systems from the self-assembly of partially alkylated poly(2-dimethyl aminoethyl) methacrylate with inherent antimicrobial property and sustained release behaviour
European Polymer Journal
https://doi.org/10.1016/j.eurpolymj.2022.111559