Case Report
BibTex RIS Cite

Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu

Year 2018, Volume: 18 Issue: 3, 454 - 457, 28.09.2018
https://doi.org/10.17098/amj.461663

Abstract

Hipokalemi
sık görülen elektrolit bozukluklarından biridir. Azalmış potasyum alımı, hücre
içine artmış potasyum geçişi, gastrointestinal sistemden ya da üriner sistemden
artmış potasyum kaybı, ilaçlar gibi pek çok faktör hipokalemiye neden olabilir.
Gitelman sendromu hipokaleminin eşlik ettiği nadir görülen otozomal resesif
hastalıktır. Burada hipertiroidi nedeniyle tetkik edilirken Gitelman sendromu
tanısı konulan bir olguyu sunduk.

References

  • 1. Monnens L, Bindels R, Grünfeld JP. Gitelman syndrome comes of age. Nephrol Dial Transplant 1998;13(7):1617-9.
  • 2. Blanchard A, Bockenhauer D, Bolignano D, et al. Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2017;91(1):24-33.
  • 3. Cruz DN, Simon DB, Nelson-Williams C, et al. Mutations in the Na-Cl cotransporter reduce blood pressure in humans. Hypertension 2001;37(6):1458-64.
  • 4. De Jong JC, Van Der Vliet WA, Van Den Heuvel LP, Willems PH, Knoers PH, Bindels RJ. Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome. J Am Soc Nephrol 2002;13(6):1442-8.
  • 5. Vargas-Poussou R, Dahan K, Kahila D, et al. Spectrum of mutations in Gitelman syndrome. J Am Soc Nephrol 2011;22(4):693-703.
  • 6. Ea HK, Blanchard A, Dougados M, Roux C. Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome. J Rheumatol 2005;32(9):1840-2.
  • 7. Berry MR, Robinson C, Karet Frankl FE. Unexpected clinical sequelae of Gitelman syndrome: hypertension in adulthood is common and females have higher potassium requirements. Nephrol Dial Transplant 2013;28(6):1533-42.
  • 8. Stein JH. The pathogenetic spectrum of Bartter's syndrome. Kidney Int 1985;28(1):85-93.
  • 9. Blanchard A, Vargas-Poussou R, Vallet M, et al. Indomethacin, amiloride, or eplerenone for treating hypokalemia in Gitelman syndrome. J Am Soc Nephrol 2015;26(2):468-75.
  • 10. Calo LA, Marchini F, Davis PA, Rigotti P, Pagnin E, Semplicini A. Kidney transplant in Gitelman's syndrome. Report of the first case. J Nephrol 2003;16(1):144-7.

A Rare Reason of Hypokalemia in a Hyperthyroid Patient: Gitelman Syndrome

Year 2018, Volume: 18 Issue: 3, 454 - 457, 28.09.2018
https://doi.org/10.17098/amj.461663

Abstract

Hypokalemia
is one of the commonly observed electrolyte disturbances. Many factors like
decreased potassium intake, increased intracellular potassium influx, increased
excretion from the gastrointestinal system or urinary tract, and drugs can
cause hypokalemia. Gitelman syndrome is a rare autosomal recessive disease
associated with hypokalemia. Here, we presented a case who was examined for
hyperthyroidism and finally diagnosed as Gitelman syndrome.

References

  • 1. Monnens L, Bindels R, Grünfeld JP. Gitelman syndrome comes of age. Nephrol Dial Transplant 1998;13(7):1617-9.
  • 2. Blanchard A, Bockenhauer D, Bolignano D, et al. Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2017;91(1):24-33.
  • 3. Cruz DN, Simon DB, Nelson-Williams C, et al. Mutations in the Na-Cl cotransporter reduce blood pressure in humans. Hypertension 2001;37(6):1458-64.
  • 4. De Jong JC, Van Der Vliet WA, Van Den Heuvel LP, Willems PH, Knoers PH, Bindels RJ. Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome. J Am Soc Nephrol 2002;13(6):1442-8.
  • 5. Vargas-Poussou R, Dahan K, Kahila D, et al. Spectrum of mutations in Gitelman syndrome. J Am Soc Nephrol 2011;22(4):693-703.
  • 6. Ea HK, Blanchard A, Dougados M, Roux C. Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome. J Rheumatol 2005;32(9):1840-2.
  • 7. Berry MR, Robinson C, Karet Frankl FE. Unexpected clinical sequelae of Gitelman syndrome: hypertension in adulthood is common and females have higher potassium requirements. Nephrol Dial Transplant 2013;28(6):1533-42.
  • 8. Stein JH. The pathogenetic spectrum of Bartter's syndrome. Kidney Int 1985;28(1):85-93.
  • 9. Blanchard A, Vargas-Poussou R, Vallet M, et al. Indomethacin, amiloride, or eplerenone for treating hypokalemia in Gitelman syndrome. J Am Soc Nephrol 2015;26(2):468-75.
  • 10. Calo LA, Marchini F, Davis PA, Rigotti P, Pagnin E, Semplicini A. Kidney transplant in Gitelman's syndrome. Report of the first case. J Nephrol 2003;16(1):144-7.
There are 10 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Reports
Authors

Hüsniye Başer This is me

Oya Topaloğlu

Bekir Çakır This is me

Publication Date September 28, 2018
Published in Issue Year 2018 Volume: 18 Issue: 3

Cite

APA Başer, H., Topaloğlu, O., & Çakır, B. (2018). Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu. Ankara Medical Journal, 18(3), 454-457. https://doi.org/10.17098/amj.461663
AMA Başer H, Topaloğlu O, Çakır B. Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu. Ankara Med J. September 2018;18(3):454-457. doi:10.17098/amj.461663
Chicago Başer, Hüsniye, Oya Topaloğlu, and Bekir Çakır. “Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu”. Ankara Medical Journal 18, no. 3 (September 2018): 454-57. https://doi.org/10.17098/amj.461663.
EndNote Başer H, Topaloğlu O, Çakır B (September 1, 2018) Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu. Ankara Medical Journal 18 3 454–457.
IEEE H. Başer, O. Topaloğlu, and B. Çakır, “Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu”, Ankara Med J, vol. 18, no. 3, pp. 454–457, 2018, doi: 10.17098/amj.461663.
ISNAD Başer, Hüsniye et al. “Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu”. Ankara Medical Journal 18/3 (September 2018), 454-457. https://doi.org/10.17098/amj.461663.
JAMA Başer H, Topaloğlu O, Çakır B. Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu. Ankara Med J. 2018;18:454–457.
MLA Başer, Hüsniye et al. “Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu”. Ankara Medical Journal, vol. 18, no. 3, 2018, pp. 454-7, doi:10.17098/amj.461663.
Vancouver Başer H, Topaloğlu O, Çakır B. Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu. Ankara Med J. 2018;18(3):454-7.