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In this work, several oxadiazole, thiadiazole, and triazole derivatives, as well as new Schiff bases, were prepared. Cholic acid was used as a starting material to prepare the five-membered heterocyclic compounds. The synthesized compounds were identified by FTIR and 1H,13C-NMR spectroscopy, which elucidated and confirmed the structure of the target molecules. Estimation of the biological activity of the newly produced compounds has been conducted against two types of Gram-positive and Gram-negative pathogenic bacteria.
Primary Language | English |
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Subjects | Natural Products and Bioactive Compounds, Organic Chemical Synthesis |
Journal Section | RESEARCH ARTICLES |
Authors | |
Publication Date | May 15, 2024 |
Submission Date | October 8, 2023 |
Acceptance Date | December 6, 2023 |
Published in Issue | Year 2024 Volume: 11 Issue: 2 |