Rapid synthesis of Silver Nanoparticles with Rheum ribes L Fruit Peels: Anticancer and Antimicrobial Effects with Biocompatible Structures

Yıl 2024, Cilt: 30 Sayı: 2, 386 - 399, 26.03.2024

Murat Zor Mehmet Fırat Baran Duygu Neval Sayın İpek

https://doi.org/10.15832/ankutbd.1380604

Öz

Silver nanoparticles (AgNPs) are substances with a wide range of uses. Utilizing extracts obtained from the peels of Rheum ribes L. (Rr) fruit growing in Erzurum region, silver nanoparticles were rapidly created in this study with a quick, easy, and environmentally friendly technique without harmful processes. In order to evaluate the attributes of the synthesized Rr-AgNPs, FE-SEM or TEM micrographs were utilized to characterize their morphology. A UV-visible spectrophotometer was used to assess the highest absorbance bands of RR-AgNPs. These data were used to define RR-AgNPs, which were characterized as having exclusively negative surface charges of -25 mV, spherical shape, maximum absorbance at 428 nm wavelength, and 96 nm size distribution. The effectiveness of the produced AgNPs for use in medical applications was assessed using the MTT technique with microdilution. Minimum inhibition concentrations of Rr-AgNPs for pathogen strains ranged from 0.03 to 0.50 mg/L. Additionally, it was discovered that AgNPs effectively suppressed malignant cells, with rates of 86.27%, 74.67%, and 73.49%, in the investigation of the anticancer effects of AgNPs. Healthy cells were not subject to any inhibitory effects at the same concentrations.

Anahtar Kelimeler

Rr-AgNPs, Fruit peels, FTIR, TGA, UV-Vis.

Etik Beyan

Bu çalışma kapsamında etik kurul gerektirecek çalışma yoktur.

Destekleyen Kurum

yok.

Teşekkür

yok

Kaynakça

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