BibTex RIS Kaynak Göster

Olanzapin Kullanımına Bağlı Derin Ven Trombozu

Yıl 2011, Cilt: 2 Sayı: 4, 30 - 32, 01.10.2011

Öz

Atipik antipsikotik ilaçlar ekstrapramidal yan etki oluşturma
riskleri düşük olduğu için başta şizofreni ve manide giderek artan
oranlarda kullanılmaktadır. Atipik antipsikotik ilaç kullanımında
başta obezite ve dislipidemi gibi birçok metabolik yan etki
oluşabilmektedir. Atipik antipsikotik ilaç kullanımı ve venöz
tromboemboli gelişimi arasında ilişki olabileceğini gösteren
çalışmaların sayısı giderek artmaktadır. Acil servisimize bacakta
ağrı ve şişlik sebebiyle başvuran ve bipolar bozukluk nedeniyle
olanzapin kulllanan 33 yaşında erkek hastada derin ven trombozu
saptadık. Biz bu olgu sunumunda venöz tromboemboli gelişimi
için risk faktörlerinin olmadığı hastada olanzapine kullanımının
derin ven trombozuna yol açabileceğini tartıştık.

Kaynakça

  • Tomassen R, Vandenbroucke JP, Rosendal FR. Antipsychotic Medication and Venous Thrombosis. British Journal of Psychiatry. 2001;179:63-66.
  • Jonsson A, Horvath-Puho E, Hagg S, Pedersen L, Sorensen HT. Antipsychotics and Risk of Venous Thromboembolism: A population- Based Case- Control Study. Clinical Epidemiology 2009;1:19-26.
  • Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: Clinical Outcomes in the International Cooperative Pulmonary Em- bolism Registry (ICOPER). Lancet 1999;353 (9162):1386-1389.
  • Anderson FA Jr, Spencer FA. Risk Factors for Venous Thrombo- embolism. Circulation. 2003;107: 9-16.
  • Van Neste E, Verbruggen W, Leysen M. Deep Venous Thrombosis and Pulmonary Embolism in Psychiatric Settings. European Jour- nal of Psychiatry. 2009;23(1):19-30.
  • Yeh J, Lee A. Clozapine-Induced Pulmonary Embolism: A Case Re- port and Literature Review. Hospital Pharmacy. 2009;44(1):36-40.
  • Hagg S, Bate A, Stahl M, Spigset O. Associations Between Ve- nous Thromboembolism and Antipsychotics. Drug Safety. 2008;31(8):685-694.
  • Maempel JFZ, Darmanin G, Naeem K, Patel M. Olanzapine and Pulmonary Embolism, A Rare Association: A Case Report. Cases Journal 2010;3:36.
  • Kannan R, Molina DK. Olanzapine: A New Risk Factor for Pul- monary Embolus?. American Journal of Forensic Medicine and Pathology. 2008;29(4):368-370.
  • Liperoti R, Pedone C, Lapane KL, Mor V. Venous Thromboem- bolism Among Elderly Patients Treated with Atypical and Con- ventional Antipsychotic Agents. Archives of Internal Medicine. 2005;165:2677-2682.

Olanzapine Induced Deep Venous Thrombosis

Yıl 2011, Cilt: 2 Sayı: 4, 30 - 32, 01.10.2011

Öz

Cause of a lower risk of extrapyramidal side effects atypical antipsychotic drugs are primarily being used more frequently in schizophrenia and mania. Many metabolic side effects particularly such as obesity and dyslipidemia may occur in the use of atypical antipsychotic drugs. Numbers of studies that show a relationship between atypical antipsychotic use and the development of venous thromboembolism have been increasing. We discovered deep venous thrombosis in 33year- old male patient, who had been using olanzapine due to bipolar disorder, admitted to our emergency service with leg pain and swelling. In this case report we discussed that in a patient without risk factors for developing venous thromboembolism, the use of olanzapine may lead to deep venous thrombosis

Kaynakça

  • Tomassen R, Vandenbroucke JP, Rosendal FR. Antipsychotic Medication and Venous Thrombosis. British Journal of Psychiatry. 2001;179:63-66.
  • Jonsson A, Horvath-Puho E, Hagg S, Pedersen L, Sorensen HT. Antipsychotics and Risk of Venous Thromboembolism: A population- Based Case- Control Study. Clinical Epidemiology 2009;1:19-26.
  • Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: Clinical Outcomes in the International Cooperative Pulmonary Em- bolism Registry (ICOPER). Lancet 1999;353 (9162):1386-1389.
  • Anderson FA Jr, Spencer FA. Risk Factors for Venous Thrombo- embolism. Circulation. 2003;107: 9-16.
  • Van Neste E, Verbruggen W, Leysen M. Deep Venous Thrombosis and Pulmonary Embolism in Psychiatric Settings. European Jour- nal of Psychiatry. 2009;23(1):19-30.
  • Yeh J, Lee A. Clozapine-Induced Pulmonary Embolism: A Case Re- port and Literature Review. Hospital Pharmacy. 2009;44(1):36-40.
  • Hagg S, Bate A, Stahl M, Spigset O. Associations Between Ve- nous Thromboembolism and Antipsychotics. Drug Safety. 2008;31(8):685-694.
  • Maempel JFZ, Darmanin G, Naeem K, Patel M. Olanzapine and Pulmonary Embolism, A Rare Association: A Case Report. Cases Journal 2010;3:36.
  • Kannan R, Molina DK. Olanzapine: A New Risk Factor for Pul- monary Embolus?. American Journal of Forensic Medicine and Pathology. 2008;29(4):368-370.
  • Liperoti R, Pedone C, Lapane KL, Mor V. Venous Thromboem- bolism Among Elderly Patients Treated with Atypical and Con- ventional Antipsychotic Agents. Archives of Internal Medicine. 2005;165:2677-2682.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA83ND83AY
Bölüm Araştırma Makalesi
Yazarlar

Sinan Genç

Cuma Yıldırım Bu kişi benim

Pınar Yarbil Bu kişi benim

Hasan Kılıç Bu kişi benim

Behçet Al Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2011
Gönderilme Tarihi 1 Ekim 2011
Yayımlandığı Sayı Yıl 2011 Cilt: 2 Sayı: 4

Kaynak Göster

APA Genç, S., Yıldırım, C., Yarbil, P., Kılıç, H., vd. (2011). Olanzapine Induced Deep Venous Thrombosis. Journal of Emergency Medicine Case Reports, 2(4), 30-32.
AMA Genç S, Yıldırım C, Yarbil P, Kılıç H, Al B. Olanzapine Induced Deep Venous Thrombosis. Journal of Emergency Medicine Case Reports. Ekim 2011;2(4):30-32.
Chicago Genç, Sinan, Cuma Yıldırım, Pınar Yarbil, Hasan Kılıç, ve Behçet Al. “Olanzapine Induced Deep Venous Thrombosis”. Journal of Emergency Medicine Case Reports 2, sy. 4 (Ekim 2011): 30-32.
EndNote Genç S, Yıldırım C, Yarbil P, Kılıç H, Al B (01 Ekim 2011) Olanzapine Induced Deep Venous Thrombosis. Journal of Emergency Medicine Case Reports 2 4 30–32.
IEEE S. Genç, C. Yıldırım, P. Yarbil, H. Kılıç, ve B. Al, “Olanzapine Induced Deep Venous Thrombosis”, Journal of Emergency Medicine Case Reports, c. 2, sy. 4, ss. 30–32, 2011.
ISNAD Genç, Sinan vd. “Olanzapine Induced Deep Venous Thrombosis”. Journal of Emergency Medicine Case Reports 2/4 (Ekim 2011), 30-32.
JAMA Genç S, Yıldırım C, Yarbil P, Kılıç H, Al B. Olanzapine Induced Deep Venous Thrombosis. Journal of Emergency Medicine Case Reports. 2011;2:30–32.
MLA Genç, Sinan vd. “Olanzapine Induced Deep Venous Thrombosis”. Journal of Emergency Medicine Case Reports, c. 2, sy. 4, 2011, ss. 30-32.
Vancouver Genç S, Yıldırım C, Yarbil P, Kılıç H, Al B. Olanzapine Induced Deep Venous Thrombosis. Journal of Emergency Medicine Case Reports. 2011;2(4):30-2.