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In this work, several oxadiazole, thiadiazole, and triazole derivatives, as well as new Schiff bases, were prepared. Cholic acid was used as a starting material to prepare the five-membered heterocyclic compounds. The synthesized compounds were identified by FTIR and 1H,13C-NMR spectroscopy, which elucidated and confirmed the structure of the target molecules. Estimation of the biological activity of the newly produced compounds has been conducted against two types of Gram-positive and Gram-negative pathogenic bacteria.
Cholic acid heterocyclic Schiff bases thiadiazoles oxadiazoles pathogenic bacteria
Birincil Dil | İngilizce |
---|---|
Konular | Doğal Ürünler ve Biyoaktif Bileşikler, Organik Kimyasal Sentez |
Bölüm | ARAŞTIRMA MAKALELERİ |
Yazarlar | |
Yayımlanma Tarihi | 15 Mayıs 2024 |
Gönderilme Tarihi | 8 Ekim 2023 |
Kabul Tarihi | 6 Aralık 2023 |
Yayımlandığı Sayı | Yıl 2024 Cilt: 11 Sayı: 2 |