SERVİKAL YÜKSEK DERECELİ SKUAMOZ İNTRAEPİTELYAL LEZYON İÇİN DE⁄ERLENDİRME SIRASINDA İNSİDENTAL OLARAK SAPTANAN İLERİ EVRE UTERİN LEİOMYOSARKOM: OLGU SUNUMU
Öz
Uterin leiomyosarkom (LMS), kadın genital yol maligniteleri arasında
nadir olarak saptanan ve endometrium kanserine göre daha agresif
seyirli tümörlerdir. Diğer kanserlerde olduğu gibi, erken tanı
prognoza olumlu katkı sağlar. Hastalarda genellikle postmenopozal
vajinal kanama veya karın ağrısı gibi semptomlar bulunmakla beraber,
tamamen asemptomatik olgularla da karşılaşılabilir. Bu yazıda,
servikste yüksek dereceli skuamoz intraepitelyal lezyon (HSIL) nedeniyle
refere edilen, ayrıntılı inceleme neticesinde ileri evre LMS saptanan
bir olgu sunulmaktadı
Anahtar Kelimeler
Uterin Leiomyosarkom Yüksek Dereceli Skuamoz İntraepitelyal Lezyon HSIL Postmenopozal Kanama.
Kaynakça
- 1. Forney JP, Buschbaum HJ. Classifying, staging, and treating uterine sarcomas. Contemp Ob Gyn. 1981;18(3):47.
- 2. Amant F, Coosemans A, Debiec-Rychter M, Timmerman D, Vergote I. Clinical management of uterine sarcomas. Lancet Oncol. 2009;10(12):1188-98. Epub 2009/12/05.
- 3. Bergman L, Beelen ML, Gallee MP, Hollema H, Benraadt J, van Leeuwen FE. Risk and prognosis of endometrial cancer after tamoxifen for breast cancer. Comprehensive Cancer Centres’ ALERT Group. Assessment of Liver and Endometrial cancer Risk following Tamoxifen. Lancet. 2000;356(9233):881-7. Epub 2000/10/19.
- 4. Leibsohn S, d’Ablaing G, Mishell DR, Jr., Schlaerth JB. Leiomyosarcoma in a series of hysterectomies performed for presumed uterine leiomyomas. Am J Obstet Gynecol. 1990;162(4):968-74; discussion 74-6. Epub 1990/04/01.
- 5. Rose PG, Piver MS, Tsukada Y, Lau T. Patterns of metastasis in uterine sarcoma. An autopsy study. Cancer. 1989;63(5):935-8. Epub 1989/03/01.
- 6. Bartsich EG, Bowe ET, Moore JG. Leiomyosarcoma of the uterus. A 50-year review of 42 cases. Obstet Gynecol. 1968;32(1):101-6. Epub 1968/07/01.
- 7. Major FJ, Blessing JA, Silverberg SG, Morrow CP, Creasman WT, Currie JL, et al. Prognostic factors in earlystage uterine sarcoma. A Gynecologic Oncology Group study. Cancer. 1993;71(4 Suppl):1702-9. Epub 1993/02/15.
- 8. Leitao MM, Brennan MF, Hensley M, Sonoda Y, Hummer A, Bhaskaran D, et al. Surgical resection of pulmonary and extrapulmonary recurrences of uterine leiomyosarcoma. Gynecol Oncol. 2002;87(3):287-94. Epub 2002/12/07.
Öz
Uterin leiomyosarcoma (LMS) is a rare female genital tract malignancy
with an aggressive clinical course with respect to endometrial
cancer. Early diagnosis is associated with a more favorable prognosis.
Although patients generally present with symptoms such as postmenopausal
bleeding and pelvic pain, entirely asymptomatic cases
may also be encountered. In this paper, a case that was initially
referred for high grade squamous intraepithelial lesion of the cervix,
consequently diagnosed with advanced stage LMS after detailed
examination is reported
Anahtar Kelimeler
Uterine Leiomyosarcoma High Grade Squamous Intraepithelial Lesion HSIL Postmenopausal Bleeding.
Kaynakça
- 1. Forney JP, Buschbaum HJ. Classifying, staging, and treating uterine sarcomas. Contemp Ob Gyn. 1981;18(3):47.
- 2. Amant F, Coosemans A, Debiec-Rychter M, Timmerman D, Vergote I. Clinical management of uterine sarcomas. Lancet Oncol. 2009;10(12):1188-98. Epub 2009/12/05.
- 3. Bergman L, Beelen ML, Gallee MP, Hollema H, Benraadt J, van Leeuwen FE. Risk and prognosis of endometrial cancer after tamoxifen for breast cancer. Comprehensive Cancer Centres’ ALERT Group. Assessment of Liver and Endometrial cancer Risk following Tamoxifen. Lancet. 2000;356(9233):881-7. Epub 2000/10/19.
- 4. Leibsohn S, d’Ablaing G, Mishell DR, Jr., Schlaerth JB. Leiomyosarcoma in a series of hysterectomies performed for presumed uterine leiomyomas. Am J Obstet Gynecol. 1990;162(4):968-74; discussion 74-6. Epub 1990/04/01.
- 5. Rose PG, Piver MS, Tsukada Y, Lau T. Patterns of metastasis in uterine sarcoma. An autopsy study. Cancer. 1989;63(5):935-8. Epub 1989/03/01.
- 6. Bartsich EG, Bowe ET, Moore JG. Leiomyosarcoma of the uterus. A 50-year review of 42 cases. Obstet Gynecol. 1968;32(1):101-6. Epub 1968/07/01.
- 7. Major FJ, Blessing JA, Silverberg SG, Morrow CP, Creasman WT, Currie JL, et al. Prognostic factors in earlystage uterine sarcoma. A Gynecologic Oncology Group study. Cancer. 1993;71(4 Suppl):1702-9. Epub 1993/02/15.
- 8. Leitao MM, Brennan MF, Hensley M, Sonoda Y, Hummer A, Bhaskaran D, et al. Surgical resection of pulmonary and extrapulmonary recurrences of uterine leiomyosarcoma. Gynecol Oncol. 2002;87(3):287-94. Epub 2002/12/07.
Ayrıntılar
| Diğer ID | JA32RS27DY |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Nisan 2013 |
| Gönderilme Tarihi | 1 Nisan 2013 |
| Yayımlandığı Sayı | Yıl 2013 Cilt: 16 Sayı: 2 |