Year 2017, Volume 13, Issue 1, Pages 125 - 138 2017-03-30

Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent

Duygu Ersen [1] , Müge Gemili [2] , Hayati Sarı [3] , Yahya Nural [4]

296 313

In this study, acid dissociation constants of 5,5-diphenylpyrrolidine N-aroylthiourea derivatives, exhibiting anti(myco)bacterial activity, were determined by potentiometric titration in 30% (v/v) acetonitrile-water hydroorganic solventat 25 ± 0.1 °C, at an ionic background of 0.1 mol / L of NaCl using the HYPERQUAD computer program. Three acid dissociation constants were determined for each compound 1a-e and we suggest that these acid dissociation constants are related to the carboxyl, enol and enthiol groups. Stability constants of their Pt(II) and Ni(II) complexes were also determined by potentiometric titration under the same conditions stated above using the HYPERQUAD computer program. The ligands behave as bidentate and bind to the metal atom via the S and O atoms. In various pH conditions, the different complex forms were formulated as ML2, MHL2, MH2L2, MH3L2, MH4L2, MH5L2 and MH-4L2 between Pt2+/Ni2+ ions and 5,5-diphenylpyrrolidine N-aroylthioureas. Stability constants of the complexes show that the ligands 1a-e form complexes with Pt(II) and Ni(II) metals as 2:1. The stability of the complexes formed by the ligands and platinum were found to follow the order: 3d > 3a > 3e > 3c > 3b. The stability of the complexes formed by the ligands and nickel were found to follow the order: 4d > 4c > 4a > 4b > 4e. As a result, generally the platinum complexes formed with these ligands are more stable than their nickel complexes.


Acid dissociation constant, Aroylthiourea, 5, 5-Diphenylpyrrolidine, Nickel, Platinum, Stability constant
  • Saeed, A.; Flörke, U.; Erben, M.F. A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3-(substituted) thioureas. J. Sulfur. Chem. 2014; 35, 318-355.
Subjects Engineering
Journal Section Articles
Authors

Author: Duygu Ersen

Author: Müge Gemili

Author: Hayati Sarı

Author: Yahya Nural

Bibtex @research article { cbayarfbe302657, journal = {Celal Bayar University Journal of Science}, issn = {1305-130X}, eissn = {1305-1385}, address = {Celal Bayar University}, year = {2017}, volume = {13}, pages = {125 - 138}, doi = {10.18466/cbayarfbe.302657}, title = {Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent}, key = {cite}, author = {Ersen, Duygu and Gemili, Müge and Sarı, Hayati and Nural, Yahya} }
APA Ersen, D , Gemili, M , Sarı, H , Nural, Y . (2017). Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent. Celal Bayar University Journal of Science, 13 (1), 125-138. DOI: 10.18466/cbayarfbe.302657
MLA Ersen, D , Gemili, M , Sarı, H , Nural, Y . "Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent". Celal Bayar University Journal of Science 13 (2017): 125-138 <http://dergipark.org.tr/cbayarfbe/issue/28447/302657>
Chicago Ersen, D , Gemili, M , Sarı, H , Nural, Y . "Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent". Celal Bayar University Journal of Science 13 (2017): 125-138
RIS TY - JOUR T1 - Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent AU - Duygu Ersen , Müge Gemili , Hayati Sarı , Yahya Nural Y1 - 2017 PY - 2017 N1 - doi: 10.18466/cbayarfbe.302657 DO - 10.18466/cbayarfbe.302657 T2 - Celal Bayar University Journal of Science JF - Journal JO - JOR SP - 125 EP - 138 VL - 13 IS - 1 SN - 1305-130X-1305-1385 M3 - doi: 10.18466/cbayarfbe.302657 UR - https://doi.org/10.18466/cbayarfbe.302657 Y2 - 2019 ER -
EndNote %0 Celal Bayar University Journal of Science Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent %A Duygu Ersen , Müge Gemili , Hayati Sarı , Yahya Nural %T Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent %D 2017 %J Celal Bayar University Journal of Science %P 1305-130X-1305-1385 %V 13 %N 1 %R doi: 10.18466/cbayarfbe.302657 %U 10.18466/cbayarfbe.302657
ISNAD Ersen, Duygu , Gemili, Müge , Sarı, Hayati , Nural, Yahya . "Acid Dissociation Constants of 5,5-Diphenylpyrrolidine N-Aroylthioureas and Stability Constants of their Pt(II) and Ni(II) Complexes in Acetonitrile-Water Hydroorganic Solvent". Celal Bayar University Journal of Science 13 / 1 (March 2017): 125-138. https://doi.org/10.18466/cbayarfbe.302657