Determination of Antioxidant Effect of Walnut (Juglans regia L.) on Lung and Muscle Tissue

Yıl 2019, Cilt: 2 Sayı: 1, 29 - 39, 30.04.2019

Bedia Bati İsmail Çelik Abdullah Turan

Öz

This study was to
investigate the antioxidant role of Juglans
regia L. (walnut) against ethanol-induced oxidative stress in lung and
muscle tissues. Female Albino
36 rats were divided into six groups and treated as follows: I (control), II
(20% ethanol), III (10%walnut), IV (20% ethanol + 10%walnut), V (5% walnut) and
VI (20% ethanol + 5% walnut). The
rats were sacrificed after 50 days of administration and the tissues
were analyzed after isolation. According to the results, it was found that the
increased malondialdehyde (MDA) content owing to the alcohol-induced oxidative
stress in both tissues decreased in the walnut treated tissues. In addition alcohol
and alcohol + walnut treatment of nutritional supplemented rats changed catalase
(CAT), glutathione peroxidase (GPx), glutathione S-transferase (GST) and superoxide
dismutase (SOD) content and antioxidant defence system (ADS) components
compared to control rats. As a
result, ethanol has been shown to cause fluctuations in ADS components as a
result of oxidative stress in rats and it can be said that walnut has a
curative effect on the this complications caused by oxidative stress.

Anahtar Kelimeler

Juglans regia L., Antioxidant defense system, Malondialdehyde

Kaynakça

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