Malakoplakia of Prostate Which Diagnosed by Transrectal Ultrasound Guided Biopsy of the Prostate

Abstract

Malakoplakia is a rare chronic inflammatory disease of genitourinary system. Malakoplakia of prostate may be present with prostatitis and acute urinary tract obstruction. Malakoplakia due to infection may cause high prostate specific antigen (PSA) values and gives hypoechoic image in transrectal ultrasound which is indistinguishable from prostate cancer. It is frequently misdiagnosed as a malign condition and histopathological examination is required for a definitive diagnosis. In this case report, we present a patient who presented to our hospital with prostatism symptoms and high PSA levels. Although primary clinical consideration was as prostate malignancy, this case was diagnosed as malakoplakia after histopathologic examination.

 

Keywords

• Malakoplakia,prostate biopsy,prostate cancer

Transrektal Ultrason Eşliğinde Prostat Biyopsisi ile Tanı Konulan Prostat Malakoplakisi

Öz

Malakoplaki genitoüriner sistemin nadir görülen kronik inflamatuar bir hastalığıdır. Prostat malakoplaki prostatit ve akut üriner sistem obstrüksiyonu ile prezente olabilir. Malakoplaki enfeksiyon nedeniyle yüksek prostat spesifik antijen (PSA) değerlerine neden olabilir ve transrektal ultrasonda hipoekoik görüntü vererek prostat kanserinden ayırt edilemez. Sıklıkla malignite olarak yanlış tanı alır ve histopatolojik inceleme kesin tanı için gereklidir. Bu olgu sunumunda, biz prostatizm ve yüksek PSA düzeyleri ile hastanemize başvuran hastayı sunuyoruz. Birincil klinik düşünce prostat malignitesi olmasına rağmen, bu olguda histopatolojik incelemede malakoplaki tanısı konuldu.

Anahtar Kelimeler

• Malakoplaki,prostat biyopsisi,prostat kanseri

References

1. 1.Michaelis L, Gutmann C. Ueber einschliisse in Blasentumoren. Ztschr Klin Med. 1902;47:208-15.
2. 2. Gupta K, Thakur S. Pulmonary malakoplakia: a report of two cases. Indian J Pathol Microbiol. 2011;54:133-5.
3. 3. P. Tuzlalı, A. A. Iğdem, M. B. C. Balcı, et al. “The malakoplakia case which has been diagnosed by prostate tru-cut biopsy: a case report ”. Turk J of Urol. 2001 ;27:98–100.
4. 4. Wagner D, Joseph J, Huang J, et al. Malakoplakia of the prostate on needle core biopsy: a case report and review of literature. Int J Surg Pathol. 2007; 15:86-9. 5. Carruthers NC. Malakoplakia; report of a case. Can J Surg. 1959;2:213-214.
5. 6. S. N. Görgel, U. Balci, A. A. Sari, etal. “Malakoplakia of the prostate diagnosed by elevated PSA level and transrectal prostate biopsy”. Kaohsiung Journal Med Sci. 2011; 27:163–165.
6. 7. Long JP Jr, Althausen AF. Malacoplakia: a 25-year experience with a review of the literature. J Urol. 1989;141:1328-31.
7. 8. Stanton MJ, Maxted W. Malacoplakia: a study of the literature and current concepts of pathogenesis, diagnosis and treatment. J Urol. 1981;125:139-46.
8. 9. Curran FT. Malacoplakia of bladder. Br J Urol. 1987; 59: 559-63.

9. 10. Campbell Walsh Urology. 10th ed. Edited by Wein AJ. Philadelphia, PA: Elsevier Saunders; 2012.