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Malignensi, Hiperparatiroidizm, Hipokalsiüri ve Yüksek Doz Vitamin D Kullanım Öyküsü Olan Hiperkalsemik Bir Hasta;Yaklaşım ve Kısa Literatür İncelemesi

Year 2015, , 286 - 289, 01.09.2015

Emin Murat Akbaş Adem Güngör Aysu Timuroğlu Hünkar Ağgül Nergis Akbaş

https://doi.org/10.5505/abantmedj.2015.71601

Abstract

Hiperkalsemi, sık görülen bir medikal problem olup pek çok sebebi vardır. En sık rastlanılan sebepleri malign hastalıklar ve primer hiperparatiroidizmdir. Ek olarak granülomatöz hastalıklar, ilaçlara bağlı hiperkalsemi ve çeşitli endokrin hastalıklar da hiperkalsemiye sebep olabilir. Hiperkalseminin klinik prezantasyonu ve prognozu; hiperkalsemi gelişme hızı, hiperkalseminin şiddeti ve altta yatan sebeplere bağlıdır. Birçok hasta konstitüsyonel, nörolojik, gastrointestinal semptomlar ve renal hastalık semptom ve bulguları ile başvurabilirler. Ciddi hiperkalsemide, hızlı ve etkili bir tedavi hayat kurtarıcıdır. Raporumuzda, merkezimize hiperkalsemi ile başvurup; malignite, hiperparatiroidizm, hipokalsiüri, tiazid diüretiği ve aktif-inaktif D vitamini kullanımı gibi bir çok hiperkalsemi sebebi olan bir hastaya yaklaşımımızı ve literatür bilgisini sunmayı amaçladık.

Keywords

Anahtar hiperparatiroidi hipokalsiüri vitamin D

References

  • 1. Frolich A. Prevalence of hypercalcaemia in normal and in hospital populations. Dan Med Bull. 1998; 45: 436-9.
  • 2. Makras P, Papapoulos SE. Medical treatment of hypercalcaemia. Hormones. 2009; 8: 83- 95.
  • 3. French S, Subauste J, Geraci S. Calcium abnormalities in hospitalized patients. South Med J. 2012; 105: 231-7.
  • 4. Ozkan B, Hatun S, Bereket A. Vitamin D intoxication. Turk J Pediatr. 2012; 54: 93-8.
  • 5. Zittermann A, Prokop S, Gummert JF, Borgermann J. Safety issues of vitamin D supplementation. Anticancer Agents Med Chem. 2013; 13: 4-10.
  • 6. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011; 96: 53-8.
  • 7. Christensen SE, Nissen PH, Vestergaard P, Mosekilde L. Familial hypocalciuric hypercalcaemia: a review. Curr Opin Endocrinol Diabetes Obes. 2011; 18: 359-70.
  • 8. Wermers RA, Kearns AE, Jenkins GD, Melton LJ, 3rd. Incidence and clinical spectrum of thiazideassociated hypercalcemia. Am J Med. 2007; 120: 911.
  • 9. Clines GA. Mechanisms and treatment of hypercalcemia of malignancy. Curr Opin Endocrinol Diabetes Obes. 2011; 18: 339-46.

A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review

Year 2015, , 286 - 289, 01.09.2015

Emin Murat Akbaş Adem Güngör Aysu Timuroğlu Hünkar Ağgül Nergis Akbaş

https://doi.org/10.5505/abantmedj.2015.71601

Abstract

Hypercalcemia is a common medical problem which has many causes. The most common causes of hypercalcemia are malignant diseases and primary hyperparathyroidism. Additionally granulomatous diseases, medications, endocrinological diseases may cause hypercalcemia. The clinical presentation and prognosis of hypercalcemia is related to the speed of development of hypercalcemia, underlying diseases and the severity of hypercalcemia. Most patients apply with constitutional, gastrointestinal and neurological symptoms or signs and symptoms of renal disorders. In patients with severe hypercalcemia, fast and effective therapy is essential. In this report, we aimed to discuss literature and management of a patient with hypercalcemia who has numerous etiologic factors for hypercalcemia as malign disease, hyperparathyroidism, hypocalciuria, usage of thiazide diuretic and active-inactive vitamin D.

Keywords

Hypercalcemia neoplasm hyperparathyroidi hypocalciuria vitamin D

References

  • 1. Frolich A. Prevalence of hypercalcaemia in normal and in hospital populations. Dan Med Bull. 1998; 45: 436-9.
  • 2. Makras P, Papapoulos SE. Medical treatment of hypercalcaemia. Hormones. 2009; 8: 83- 95.
  • 3. French S, Subauste J, Geraci S. Calcium abnormalities in hospitalized patients. South Med J. 2012; 105: 231-7.
  • 4. Ozkan B, Hatun S, Bereket A. Vitamin D intoxication. Turk J Pediatr. 2012; 54: 93-8.
  • 5. Zittermann A, Prokop S, Gummert JF, Borgermann J. Safety issues of vitamin D supplementation. Anticancer Agents Med Chem. 2013; 13: 4-10.
  • 6. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011; 96: 53-8.
  • 7. Christensen SE, Nissen PH, Vestergaard P, Mosekilde L. Familial hypocalciuric hypercalcaemia: a review. Curr Opin Endocrinol Diabetes Obes. 2011; 18: 359-70.
  • 8. Wermers RA, Kearns AE, Jenkins GD, Melton LJ, 3rd. Incidence and clinical spectrum of thiazideassociated hypercalcemia. Am J Med. 2007; 120: 911.
  • 9. Clines GA. Mechanisms and treatment of hypercalcemia of malignancy. Curr Opin Endocrinol Diabetes Obes. 2011; 18: 339-46.
There are 9 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Report
Authors

Emin Murat Akbaş This is me

Adem Güngör This is me

Aysu Timuroğlu This is me

Hünkar Ağgül This is me

Nergis Akbaş This is me

Publication Date September 1, 2015
Submission Date May 12, 2014
Published in Issue Year 2015

Cite

APA Akbaş, E. M., Güngör, A., Timuroğlu, A., Ağgül, H., et al. (2015). A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review. Abant Medical Journal, 4(3), 286-289. https://doi.org/10.5505/abantmedj.2015.71601
AMA Akbaş EM, Güngör A, Timuroğlu A, Ağgül H, Akbaş N. A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review. Abant Med J. September 2015;4(3):286-289. doi:10.5505/abantmedj.2015.71601
Chicago Akbaş, Emin Murat, Adem Güngör, Aysu Timuroğlu, Hünkar Ağgül, and Nergis Akbaş. “A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review”. Abant Medical Journal 4, no. 3 (September 2015): 286-89. https://doi.org/10.5505/abantmedj.2015.71601.
EndNote Akbaş EM, Güngör A, Timuroğlu A, Ağgül H, Akbaş N (September 1, 2015) A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review. Abant Medical Journal 4 3 286–289.
IEEE E. M. Akbaş, A. Güngör, A. Timuroğlu, H. Ağgül, and N. Akbaş, “A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review”, Abant Med J, vol. 4, no. 3, pp. 286–289, 2015, doi: 10.5505/abantmedj.2015.71601.
ISNAD Akbaş, Emin Murat et al. “A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review”. Abant Medical Journal 4/3 (September 2015), 286-289. https://doi.org/10.5505/abantmedj.2015.71601.
JAMA Akbaş EM, Güngör A, Timuroğlu A, Ağgül H, Akbaş N. A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review. Abant Med J. 2015;4:286–289.
MLA Akbaş, Emin Murat et al. “A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review”. Abant Medical Journal, vol. 4, no. 3, 2015, pp. 286-9, doi:10.5505/abantmedj.2015.71601.
Vancouver Akbaş EM, Güngör A, Timuroğlu A, Ağgül H, Akbaş N. A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review. Abant Med J. 2015;4(3):286-9.