Abstract
Visceral leishmaniasis kala-azar , caused by protozoan parasites, is a chronic infectious disease characterized by fever, weight loss, pallor, hypergammaglobulinemia, enlargement of spleen and liver, and pancytopenia. It is an endemic disease in all Mediterranean countries including Turkey and the children are at higher risk than adults. In this disease, anemia is the most common hematological manifestation and appears to be due to many factors but the immune hemolytic anemia has been seen rarely. In this report, we presented a 2 year old child applied to our hospital with fever, splenomegaly and immune hemolytic anemia. The hematological improvement was noted after meglumin antimonate therapy within 1-2 weeks.
References
- Özbel Y, Töz ÖS, Leishmaniosis, Özcel MA. Tıbbi Parazit Hastalıkları 1. Baskı, İzmir: Mete Basım Matbaacılık Hizmetleri, 2007: 198-230.
- Reithinger R, Dujardin JC. Molecular Diagnosis of Leishmaniasis: Current Status and Future Applications. J Clin Microbiol 2007: 21- 5.
- Varma N, Naseem S. Hematologic Changes in Visceral Leishmaniasis/Kala Azar. Indian J Hematol Blood Transfus. 2010;26:78–82.
- WHO Technical Report Series: 949, Control of the Leishmaniases. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22–26 March 2010.
- Vilela RB, Bordin JO, Chiba AK, Castelo A, Barbosa MC. RBC-associated IgG in patients with visceral leishmaniasis (kala-azar): a
- prospective analysis. Transfusion 2002; 42: 1442-7.
- Çelik Ü, Leblebisatan G, Alhan E, Aksaray N. Immune hemolytic anemia in association with visceral leishmaniasis: Case report. J Pediatr Inf 2007;1:36-8.
- Dilber E, Erduran E, Işık Y. Visceral leishmaniasis and Coombs’ positive hemolytic anemia: a rare association in an infant treated with liposomal amphotericin B. Turk J Pediatr 2002; 44(4):354-6.
- Ayyıldız Orhan. Leyişmanıyazis. 35.Ulusal Hematoloji Kongresi (7-10 Ekim 2009).
Abstract
Visseral Leishmaniasis kala-azar , protozoan parazitlerin neden olduğu, ateş, kilo kaybı, solukluk, hipergamaglobulinemi, hepatosplenomegali, pansitopeni ile karakterize kronik enfeksiyöz bir hastalıktır. Tüm Akdeniz ülkelerinde endemik görülmektedir ve çocuklar erişkinlerden daha çok risk altındadır. Anemi en sık karşılaşılan hematolojik sorundur ve birçok faktöre bağlı olarak ortaya çıkmaktadır ancak immün hemolitik anemi nadir görülmektedir. Bu yazıda 2 yaşında ateş, splenomegali ve immün hemolitik anemi ile hastanemize başvuran hasta sunuldu. Hastada, meglumin antimon tedavi sonrası 1-2 hafta içinde hematolojik düzelme gözlendi.
References
- Özbel Y, Töz ÖS, Leishmaniosis, Özcel MA. Tıbbi Parazit Hastalıkları 1. Baskı, İzmir: Mete Basım Matbaacılık Hizmetleri, 2007: 198-230.
- Reithinger R, Dujardin JC. Molecular Diagnosis of Leishmaniasis: Current Status and Future Applications. J Clin Microbiol 2007: 21- 5.
- Varma N, Naseem S. Hematologic Changes in Visceral Leishmaniasis/Kala Azar. Indian J Hematol Blood Transfus. 2010;26:78–82.
- WHO Technical Report Series: 949, Control of the Leishmaniases. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22–26 March 2010.
- Vilela RB, Bordin JO, Chiba AK, Castelo A, Barbosa MC. RBC-associated IgG in patients with visceral leishmaniasis (kala-azar): a
- prospective analysis. Transfusion 2002; 42: 1442-7.
- Çelik Ü, Leblebisatan G, Alhan E, Aksaray N. Immune hemolytic anemia in association with visceral leishmaniasis: Case report. J Pediatr Inf 2007;1:36-8.
- Dilber E, Erduran E, Işık Y. Visceral leishmaniasis and Coombs’ positive hemolytic anemia: a rare association in an infant treated with liposomal amphotericin B. Turk J Pediatr 2002; 44(4):354-6.
- Ayyıldız Orhan. Leyişmanıyazis. 35.Ulusal Hematoloji Kongresi (7-10 Ekim 2009).
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | January 1, 2014 |
| Published in Issue | Year 2014 Volume: 3 Issue: 1 |