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Mixed Medullary-Follicular Carsinoma of the Thyroid: Two Case Reports

Year 2014, Volume: 3 Issue: 3, 286 - 288, 01.09.2014
https://doi.org/10.5505/abantmedj.2014.43434

Abstract

Mixed medullary and follicular cell carcinoma MMFCC of the thyroid is rare, accounting for less than 5% of thyroid medullary carcinoma. Histologically, MMFCCs are tumours showing the morphological features of both, medullary carcinoma with immunoreactive calcitonin and follicular or papillary carcinomas with immunoreactive thyroglobuline. We present two case of mixed medullary and follicular cell carcinoma in which two thyroid carcinomas.

References

  • Ueki I, Ando T, Haraguchi A, Horie I, Imai- zumi M, Hayashi T, Uga T, Usa T, Kawakami A. A case of mixed medullary and follicular cell carcinoma of the thyroid. Intern Med ;50(12):1313-6.
  • Roy M, Chen H, Sippel RS. Current unders- tanding and management of medullary thyroid cancer. Oncologist. 2013;18(10):1093-100.
  • Papotti M, Negro F, Carney JA, Bussolati G, Lloyd RV. Mixed medullary-follicular carcinoma of the thyroid. A morphological, immunohis- tochemical and in situ hybridization analysis of cases. Virchows Arch 1997 May;430(5):397
  • Biscolla RP, Ugolini C, Sculli M, Bottici V, Castagna MG, Romei C, Cosci B,Molinaro E, Faviana P, Basolo F, Miccoli P, Pacini F, Pinche- ra A, Elisei R. Medullary and papillary tumors are frequently associated in the same thyroid gland without evidence of reciprocal influence in their biologic behavior. Thyroid. 2004 Nov;14(11):946-52.
  • Kim WG, Gong G, Kim EY, Kim TY, Hong SJ, Kim WB, Shong YK. Concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma in the same thyroid should be considered as coincidental. Clin Endocrinol (Oxf) 2010 Feb;72(2):256-63.
  • Hanna AN, Michael CW, Jing X. Mixed medul- lary-follicular carcinoma of the thyroid: diag- nostic dilemmas in fine-needle aspiration cyto- logy. DiagnCytopathol 2011 Nov;39(11):862-5.
  • Volante M, Papotti M, Roth J, Saremaslani P, Speel EJ, Lloyd RV, Carney JA, Heitz PU, Busso- lati G, Komminoth P. Mixed medullary-follicular thyroid carcinoma. Molecular evidence for a dual origin of tumor components. Am J Pathol. Nov;155(5):1499-509.

Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu

Year 2014, Volume: 3 Issue: 3, 286 - 288, 01.09.2014
https://doi.org/10.5505/abantmedj.2014.43434

Abstract

Tiroidin miks medüller ve folliküler karsinomu nadir görülür, tiroid medüller karsinomlarının %5 ‘den azını oluşturur. Histolojik olarak, miks medüller ve folliküler karsinom, iki tümöründe morfolojik özelliklerini gösterir, medüller karsinom gibi immünreaktif kalsitonin, folliküler karsinom veya papiller gibi immünreaktif tiroglobulin içerir. Bu yazıda iki miks medüller ve foliküler tiroid karsinomlu olguyu sunuyoruz.

References

  • Ueki I, Ando T, Haraguchi A, Horie I, Imai- zumi M, Hayashi T, Uga T, Usa T, Kawakami A. A case of mixed medullary and follicular cell carcinoma of the thyroid. Intern Med ;50(12):1313-6.
  • Roy M, Chen H, Sippel RS. Current unders- tanding and management of medullary thyroid cancer. Oncologist. 2013;18(10):1093-100.
  • Papotti M, Negro F, Carney JA, Bussolati G, Lloyd RV. Mixed medullary-follicular carcinoma of the thyroid. A morphological, immunohis- tochemical and in situ hybridization analysis of cases. Virchows Arch 1997 May;430(5):397
  • Biscolla RP, Ugolini C, Sculli M, Bottici V, Castagna MG, Romei C, Cosci B,Molinaro E, Faviana P, Basolo F, Miccoli P, Pacini F, Pinche- ra A, Elisei R. Medullary and papillary tumors are frequently associated in the same thyroid gland without evidence of reciprocal influence in their biologic behavior. Thyroid. 2004 Nov;14(11):946-52.
  • Kim WG, Gong G, Kim EY, Kim TY, Hong SJ, Kim WB, Shong YK. Concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma in the same thyroid should be considered as coincidental. Clin Endocrinol (Oxf) 2010 Feb;72(2):256-63.
  • Hanna AN, Michael CW, Jing X. Mixed medul- lary-follicular carcinoma of the thyroid: diag- nostic dilemmas in fine-needle aspiration cyto- logy. DiagnCytopathol 2011 Nov;39(11):862-5.
  • Volante M, Papotti M, Roth J, Saremaslani P, Speel EJ, Lloyd RV, Carney JA, Heitz PU, Busso- lati G, Komminoth P. Mixed medullary-follicular thyroid carcinoma. Molecular evidence for a dual origin of tumor components. Am J Pathol. Nov;155(5):1499-509.
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Celil Alper Usluoğulları This is me

Eda Demir Onal This is me

Fevzi Balkan This is me

Serdar Balcı This is me

Reyhan Ersoy This is me

Bekir Çakır This is me

Publication Date September 1, 2014
Published in Issue Year 2014 Volume: 3 Issue: 3

Cite

APA Usluoğulları, C. A., Onal, E. D., Balkan, F., Balcı, S., et al. (2014). Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu. Abant Medical Journal, 3(3), 286-288. https://doi.org/10.5505/abantmedj.2014.43434
AMA Usluoğulları CA, Onal ED, Balkan F, Balcı S, Ersoy R, Çakır B. Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu. Abant Med J. September 2014;3(3):286-288. doi:10.5505/abantmedj.2014.43434
Chicago Usluoğulları, Celil Alper, Eda Demir Onal, Fevzi Balkan, Serdar Balcı, Reyhan Ersoy, and Bekir Çakır. “Mikst Medüller Ve Folliküler Karsinom: İki Olgunun Sunumu”. Abant Medical Journal 3, no. 3 (September 2014): 286-88. https://doi.org/10.5505/abantmedj.2014.43434.
EndNote Usluoğulları CA, Onal ED, Balkan F, Balcı S, Ersoy R, Çakır B (September 1, 2014) Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu. Abant Medical Journal 3 3 286–288.
IEEE C. A. Usluoğulları, E. D. Onal, F. Balkan, S. Balcı, R. Ersoy, and B. Çakır, “Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu”, Abant Med J, vol. 3, no. 3, pp. 286–288, 2014, doi: 10.5505/abantmedj.2014.43434.
ISNAD Usluoğulları, Celil Alper et al. “Mikst Medüller Ve Folliküler Karsinom: İki Olgunun Sunumu”. Abant Medical Journal 3/3 (September 2014), 286-288. https://doi.org/10.5505/abantmedj.2014.43434.
JAMA Usluoğulları CA, Onal ED, Balkan F, Balcı S, Ersoy R, Çakır B. Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu. Abant Med J. 2014;3:286–288.
MLA Usluoğulları, Celil Alper et al. “Mikst Medüller Ve Folliküler Karsinom: İki Olgunun Sunumu”. Abant Medical Journal, vol. 3, no. 3, 2014, pp. 286-8, doi:10.5505/abantmedj.2014.43434.
Vancouver Usluoğulları CA, Onal ED, Balkan F, Balcı S, Ersoy R, Çakır B. Mikst Medüller ve Folliküler Karsinom: İki Olgunun Sunumu. Abant Med J. 2014;3(3):286-8.