The Prognostic Parameters in Gastrointestinal and Pancreatic Neuroendocrine Tumors

Year 2012, Volume: 1 Issue: 2, 69 - 73, 01.05.2012

Gülzade Özyalvaçlı Esra Paşaoğlu Erol Rüştü Bozkurt

https://doi.org/10.5505/abantmedj.2012.02411

Abstract

OBJECTIVE: In this study, we aimed that to find the differences in prognostic parameters as diameter, mitosis, necrosis, angiolymphatic invasion, perinoral invasion and lymph node metastasis of gastroenteropancreatic neuroendocrine tumor GEPNET cases which were classified by WHO.METHODS: Between 2001-2009 in Istanbul Educational And Research Hospital Hospital Pathology Department 41 GEPNET cases were searched according to age, gender, localization, diameter, mitosis, necrosis, angiolymphatic invasion, perinoral invasion and lymph node metastasis.RESULTS: Tumor diameter was 0,76±0,78 cm in benign group and 2,82±2,86 cm in malign group p=0.006 . There was not significant differences between well differentiated neuroendocrine tumor and well differentiated neuroendocrine carcinomas for number of mitosis p>0,05 , but poorly differantiated neuroendocrine carcinomas was significantly higher number of mitosis than the others p

Keywords

gastroenteropancreatic, neuroendocrine, tumor

Gastrointestinal ve Pankreatik Nöroendokrin Tümörlerde Prognostik Parametreler

Abstract

AMAÇ: Bu çalışmada, WHO’ya göre klasifiye edilen Gastroenteropankreatik nöroendokrin tümörler GEPNET olgularında; çap, mitoz, nekroz, anjiyolenfatik invazyon, perinöral invazyon ve lenf nodu metastazı gibi prognostik parametreler açısından tümör grupları arasındaki farklılıkların ortaya konulması amaçlanmıştır.YÖNTEMLER: 2001-2009 yılları arasında İstanbul Eğitim ve Araştırma Hastanesi Patoloji Bölümünde tanı alan 41 adet gastroenteropankreatik nöroendokrin tümör olgusu yaş, cinsiyet, lokalizasyon, çap, mitoz, nekroz, anjiyolenfatik invazyon, perinöral invazyon ve lenf nodu metastazı durumu açısından incelendi.BULGULAR: Tümör çapı benign grupta 0,76±0,78 cm olup malign grupta 2,82±2,86 cm olarak saptandı p=0.006 . İyi diferansiye tümör grubu ile iyi diferansiye karsinom grubu arasında mitoz sayısı açısından istatistiksel olarak anlamlı bir farklılık bulunmazken p>0,05 , az diferansiye karsinom grubunda bu parametre diğer gruplardan anlamlı olarak yüksek bulunmuştur p

Keywords

gastroenteropankreatik, nöroendokrin, tümör

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