Research Article
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Adenotonsillektominin Pediatrik Kan Profilleri Üzerindeki Etkisi

Year 2024, Volume: 13 Issue: 3, 111 - 115
https://doi.org/10.47493/abantmedj.1559691

Abstract

Amaçlar: Adenotonsiller hipertrofi (ATH), çocuklarda sık görülen bir durumdur ve sıklıkla obstrüktif uyku apnesi ve diğer komplikasyonlara yol açar. Bu çalışmanın amacı, ATH'li çocuklarda adenotonsillektominin çeşitli kan parametreleri üzerindeki etkisini değerlendirmektir.
Materyaller ve Yöntemler: ATH ve/veya kronik tonsillit tanısı konulan ve adenotonsillektomi geçiren 84 çocuğun tıbbi kayıtları incelendi. Analiz edilen temel parametreler arasında beyaz kan hücresi sayısı (WBC), trombosit sayısı (PLT), hemoglobin (Hgb) seviyeleri, ortalama trombosit hacmi (MPV) ve trombosit dağılım genişliği (PDW) yer aldı. Kan örnekleri ameliyattan önce ve ameliyattan sonraki 1. gün, 1. hafta ve 3. ayda toplandı ve sonuçlar karşılaştırıldı.
Sonuçlar: MPV, PDW ve Hgb seviyelerinde ameliyattan hemen sonra önemli bir azalma gözlendi. İlginç bir şekilde, Hgb seviyeleri ameliyattan üç ay sonra önemli ölçüde artarak ameliyat öncesi seviyelere geri döndü veya onları geçti. Trombosit sayıları değişmeden kalsa da, RBC sayısı, Hgb ve Hct düzeylerindeki geçici azalma, cerrahi kan kaybına ve travmaya karşı fizyolojik bir tepki olduğunu düşündürmektedir. Bu parametreler, vücudun etkili telafi edici mekanizmalarını yansıtarak üç ay içinde normale dönmüştür.
Sonuç: Adenotonsillektomi, kısa vadede belirli kan parametrelerini önemli ölçüde etkiler ve çoğu değer üç aylık takipte normale döner. Bu bulgular, hematolojik değişikliklerin ameliyattan sonra izlenmesinin önemini vurgulamaktadır ve adenotonsillektominin, kan parametrelerinde geçici değişikliklere neden olsa da, çocuklarda ATH'yi yönetmek için nihayetinde güvenli ve etkili bir prosedür olduğunu düşündürmektedir.

Ethical Statement

Bu çalışma için Van eğitim ve araştırma hastanesinin klinik araştırmalar etik kurulundan onay alınmıştır. Karar no: 2016/4

Supporting Institution

Yok

Thanks

Yok

References

  • Kenna MA, Amin A. Anatomy and physiology of the oral cavity. In: Snow JB, Wackym PA, editors. Ballenger's Otorhinolaryngology Head and Neck Surgery. 17th ed. Shelton (CT): BC Decker Inc.; 2009. p. 769–74.
  • Susan S, Harold E, Jermiah CH, David J, Andrew W. Pharynx. In: Susan S, editor. Gray's Anatomy: The Anatomical Basis of Clinical Practice. 39th ed. Philadelphia (PA): Elsevier; 2005. p. 619–31.
  • Scadding G. Non-surgical treatment of adenoidal hypertrophy: the role of treating IgE-mediated inflammation. Pediatr Allergy Immunol. 2010;21(8):1095–106.
  • Kontorinis G, Schwab B. Significance of advanced hemostasis investigation in recurrent, severe post-tonsillectomy bleeding. J Laryngol Otol. 2011;125(9):952–7.
  • Liu L, Rodman C, Worobetz NE, Johnson J, Elmaraghy C, Chiang T. Topical biomaterials to prevent post-tonsillectomy hemorrhage. J Otolaryngol Head Neck Surg. 2019 Sep 6;48(1):45. doi: 10.1186/s40463-019-0368-1. PMID: 31492172; PMCID: PMC6731608.
  • Lee AC, Haché M. Pediatric anesthesia management for post-tonsillectomy bleed: current status and future directions. Int J Gen Med. 2022 Jan 4;15:63–9. doi: 10.2147/IJGM.S312866. PMID: 35027837; PMCID: PMC8749229.
  • Akelma AZ, Mete E, Cizmeci MN, Karaarslan U, Sert S. The role of mean platelet volume as an inflammatory marker in children with chronic spontaneous urticaria. Allergol Immunopathol (Madr). 2015;43(1):10–3.
  • Feng X, Li G, Qu Z, Liu L, Näsström K, Shi XQ. Comparative analysis of upper airway volume with lateral cephalograms and cone-beam computed tomography. Am J Orthod Dentofac Orthop. 2015;147(2):197–204.
  • Brodsky L. Adenotonsillar disease in children. In: Bluestone CD, Stool SE, Kenna MA, editors. Pediatric Otolaryngology. 2nd ed. Philadelphia (PA): W.B. Saunders Company; 1996. p. 15–39.
  • Richardson MA. Sore throat, tonsillitis, and adenoiditis. Med Clin North Am. 1999;83(1):75–83.
  • Alatas N, San I, Cengiz M, Iynen I, Yetkin A, Korkmaz B, et al. Mean red blood cell volume loss in tonsillectomy, adenoidectomy, and adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 2006;70(5):835–41.
  • Prasad KC, Prasad SC. Assessment of operative blood loss and the factors affecting it in tonsillectomy and adenotonsillectomy. Indian J Otolaryngol Head Neck Surg. 2011;63(4):343–8.
  • Simsek G, Karacayli C, Ozel A, Arslan B, Muluk NB, Kilic R. Blood parameters as indicators of upper airway obstruction in children with adenoid or adenotonsillar hypertrophy. J Craniofac Surg. 2015;26(3):e213–6. doi: 10.1097/SCS.0000000000001437.
  • Gümüssoy M, Atmaca S, Bilgici B, Unal R. Changes in IGF-I, IGFBP-3 and ghrelin levels after adenotonsillectomy in children with sleep-disordered breathing. Int J Pediatr Otorhinolaryngol. 2009;73(11):1653–6.

Impact of Adenotonsillectomy on Pediatric Blood Profiles

Year 2024, Volume: 13 Issue: 3, 111 - 115
https://doi.org/10.47493/abantmedj.1559691

Abstract

Objectives: Adenotonsillar hypertrophy (ATH) is a common condition in children, often leading to obstructive sleep apnea and other complications. This study aimed to evaluate the impact of adenotonsillectomy on various blood parameters in children with ATH.
Materials and Methods: Medical records of 84 children diagnosed with ATH and/or chronic tonsillitis, who underwent adenotonsillectomy, were reviewed. Key parameters analyzed included white blood cell count (WBC), platelet count (PLT), hemoglobin (Hgb) levels, mean platelet volume (MPV), and platelet distribution width (PDW). Blood samples were collected preoperatively, and at postoperative day 1, week 1, and month 3, and results were compared.
Results: A significant decrease in MPV, PDW, and Hgb levels was observed immediately postoperatively. Interestingly, Hgb levels significantly increased three months post-surgery, returning to or surpassing preoperative levels. Although platelet counts remained unchanged, the temporary reduction in RBC count, Hgb, and Hct levels suggests a physiological response to surgical blood loss and trauma. These parameters normalized within three months, reflecting the body’s effective compensatory mechanisms.
Conclusion: Adenotonsillectomy significantly impacts certain blood parameters in the short term, with most values normalizing by the three-month follow-up. These findings emphasize the importance of monitoring hematologic changes postoperatively and suggest that adenotonsillectomy, while causing temporary alterations in blood parameters, is ultimately a safe and effective procedure for managing ATH in children.

Ethical Statement

Approval for this study was obtained from the clinical research ethics committee of Van Education and Research Hospital. Decision number: 2016/4

Supporting Institution

None

Thanks

None

References

  • Kenna MA, Amin A. Anatomy and physiology of the oral cavity. In: Snow JB, Wackym PA, editors. Ballenger's Otorhinolaryngology Head and Neck Surgery. 17th ed. Shelton (CT): BC Decker Inc.; 2009. p. 769–74.
  • Susan S, Harold E, Jermiah CH, David J, Andrew W. Pharynx. In: Susan S, editor. Gray's Anatomy: The Anatomical Basis of Clinical Practice. 39th ed. Philadelphia (PA): Elsevier; 2005. p. 619–31.
  • Scadding G. Non-surgical treatment of adenoidal hypertrophy: the role of treating IgE-mediated inflammation. Pediatr Allergy Immunol. 2010;21(8):1095–106.
  • Kontorinis G, Schwab B. Significance of advanced hemostasis investigation in recurrent, severe post-tonsillectomy bleeding. J Laryngol Otol. 2011;125(9):952–7.
  • Liu L, Rodman C, Worobetz NE, Johnson J, Elmaraghy C, Chiang T. Topical biomaterials to prevent post-tonsillectomy hemorrhage. J Otolaryngol Head Neck Surg. 2019 Sep 6;48(1):45. doi: 10.1186/s40463-019-0368-1. PMID: 31492172; PMCID: PMC6731608.
  • Lee AC, Haché M. Pediatric anesthesia management for post-tonsillectomy bleed: current status and future directions. Int J Gen Med. 2022 Jan 4;15:63–9. doi: 10.2147/IJGM.S312866. PMID: 35027837; PMCID: PMC8749229.
  • Akelma AZ, Mete E, Cizmeci MN, Karaarslan U, Sert S. The role of mean platelet volume as an inflammatory marker in children with chronic spontaneous urticaria. Allergol Immunopathol (Madr). 2015;43(1):10–3.
  • Feng X, Li G, Qu Z, Liu L, Näsström K, Shi XQ. Comparative analysis of upper airway volume with lateral cephalograms and cone-beam computed tomography. Am J Orthod Dentofac Orthop. 2015;147(2):197–204.
  • Brodsky L. Adenotonsillar disease in children. In: Bluestone CD, Stool SE, Kenna MA, editors. Pediatric Otolaryngology. 2nd ed. Philadelphia (PA): W.B. Saunders Company; 1996. p. 15–39.
  • Richardson MA. Sore throat, tonsillitis, and adenoiditis. Med Clin North Am. 1999;83(1):75–83.
  • Alatas N, San I, Cengiz M, Iynen I, Yetkin A, Korkmaz B, et al. Mean red blood cell volume loss in tonsillectomy, adenoidectomy, and adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 2006;70(5):835–41.
  • Prasad KC, Prasad SC. Assessment of operative blood loss and the factors affecting it in tonsillectomy and adenotonsillectomy. Indian J Otolaryngol Head Neck Surg. 2011;63(4):343–8.
  • Simsek G, Karacayli C, Ozel A, Arslan B, Muluk NB, Kilic R. Blood parameters as indicators of upper airway obstruction in children with adenoid or adenotonsillar hypertrophy. J Craniofac Surg. 2015;26(3):e213–6. doi: 10.1097/SCS.0000000000001437.
  • Gümüssoy M, Atmaca S, Bilgici B, Unal R. Changes in IGF-I, IGFBP-3 and ghrelin levels after adenotonsillectomy in children with sleep-disordered breathing. Int J Pediatr Otorhinolaryngol. 2009;73(11):1653–6.
There are 14 citations in total.

Details

Primary Language English
Subjects Otorhinolaryngology
Journal Section Research Article
Authors

Ahmet Köder 0000-0003-4348-8109

Saffet Kılıçaslan 0000-0001-8478-3775

Early Pub Date December 19, 2024
Publication Date
Submission Date October 1, 2024
Acceptance Date November 21, 2024
Published in Issue Year 2024 Volume: 13 Issue: 3

Cite

APA Köder, A., & Kılıçaslan, S. (2024). Impact of Adenotonsillectomy on Pediatric Blood Profiles. Abant Medical Journal, 13(3), 111-115. https://doi.org/10.47493/abantmedj.1559691
AMA Köder A, Kılıçaslan S. Impact of Adenotonsillectomy on Pediatric Blood Profiles. Abant Med J. December 2024;13(3):111-115. doi:10.47493/abantmedj.1559691
Chicago Köder, Ahmet, and Saffet Kılıçaslan. “Impact of Adenotonsillectomy on Pediatric Blood Profiles”. Abant Medical Journal 13, no. 3 (December 2024): 111-15. https://doi.org/10.47493/abantmedj.1559691.
EndNote Köder A, Kılıçaslan S (December 1, 2024) Impact of Adenotonsillectomy on Pediatric Blood Profiles. Abant Medical Journal 13 3 111–115.
IEEE A. Köder and S. Kılıçaslan, “Impact of Adenotonsillectomy on Pediatric Blood Profiles”, Abant Med J, vol. 13, no. 3, pp. 111–115, 2024, doi: 10.47493/abantmedj.1559691.
ISNAD Köder, Ahmet - Kılıçaslan, Saffet. “Impact of Adenotonsillectomy on Pediatric Blood Profiles”. Abant Medical Journal 13/3 (December 2024), 111-115. https://doi.org/10.47493/abantmedj.1559691.
JAMA Köder A, Kılıçaslan S. Impact of Adenotonsillectomy on Pediatric Blood Profiles. Abant Med J. 2024;13:111–115.
MLA Köder, Ahmet and Saffet Kılıçaslan. “Impact of Adenotonsillectomy on Pediatric Blood Profiles”. Abant Medical Journal, vol. 13, no. 3, 2024, pp. 111-5, doi:10.47493/abantmedj.1559691.
Vancouver Köder A, Kılıçaslan S. Impact of Adenotonsillectomy on Pediatric Blood Profiles. Abant Med J. 2024;13(3):111-5.