Is metabolic syndrome related to postmenopausal osteoporosis? A retrospective study

Year 2018, , 71 - 74, 20.07.2018

Elif Turan , Hafize Kızılkaya Yalçın Aral

https://doi.org/10.25000/acem.419847

Abstract

Aim: To evaluate the difference between postmenopausal women with and without
osteoporosis in terms of metabolic syndrome.

Methods: A total of 98 postmenopausal women younger than 65 years, were enrolled
in the study. According to the
bone mineral density examination; 49 participants who had T-score>−2.5 at
the spine or/and femoral neck were included in the group without osteoporosis
(Group 1), and 49 participants who had T-score≤−2.5 at the spine or/and femoral
neck were included in the osteoporosis group (Group 2). Patient’s profile which
included all demographic data, particularly anthropometric evaluation
and medical history was
obtained. Serum fasting glucose, lipid profiles and 25 OH vitamin D levels were
also recorded.

Results: Age (p=0.001), menopausal age (p=0.003), systolic
blood pressure (p=0.004) and diastolic blood pressure (p=0.001) of Group 2 were
significantly higher than Group 1. There were no significant difference in
terms of body mass index, weight, lipid profiles, serum calcium and serum 25 OH
vitamin D levels among the groups (p>0.05 for all). Twenty five (51%) of 49
women in Group 1 and 36 (73%) of 49 women in Group 2 had metabolic syndrome.
There was a statistically significant relationship between osteoporosis and the
metabolic syndrome (p=0.037).

Conclusion: Our results demonstrated that osteoporosis is related with the
metabolic syndrome in postmenopausal women.

Keywords

metabolic syndrome, osteoporosis, menopause

Metabolik sendrom postmenopozal osteoporoz ile ilişkili midir? Retrospektif bir çalışma

Abstract

Amaç: Postmenopozal kadınlarda, osteoporoz ile metabolik sendrom
arasındaki ilişkiyi değerlendirmek.

Yöntemler: 65 yaşın altında toplam 98
postmenopozal kadın çalışmaya dahil edildi. Kemik mineral dansitometre sonucuna
göre; lumber ve/veya femur boyun T skoru>-2.5 olan 49 hasta postmenopozal
osteoporoz olmayan gruba (Grup 1), T skoru≤-2.5 olan 49 hasta postmenopozal osteoporoz
grubuna (Grup 2) dahil edildi. Tüm demografik verileri içeren hasta profili,
antropometrik değerlendirme ve tıbbi öykü kaydedildi. Serum açlık glukozu,
lipit profili ve serum 25 OH D vitamin seviyesi de kaydedildi.

Bulgular: Grup 1 ve Grup 2 karşılaştırıldığında;
yaş (p=0.001), menopoz yaşı (p=0.003) sistolik kan basıncı (p=0.004) ve diyastolik
kan basıncı (p=0.001) Grup 2’de Grup 1’e göre anlamlı şekilde daha yüksekti. Vücut
kitle indeksi, boy, kilo, lipid profili, serum 25 OH vitamin D düzeyleri açısından
gruplar arasında anlamlı fark yoktu (p>0.05). Osteoporozu olan 49 hastanın
36’sında (%73), osteoporozu olmayan 49 hastanın ise 25’inde (%51) metabolik sendrom
tespit edildi. Osteoporoz ile metabolik sendrom arasında istatistiksel olarak anlamlı
ilişki tespit edildi (p=0,037).

Sonuç: Postmenopozal kadınlarda osteoporoz ile metabolik
sendrom arasında anlamlı ilişki olduğu tespit edilmiştir.

Keywords

Metabolik sendrom, menopoz, osteoporoz

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