Cervical blood flow velocity values in patients with unilateral intracranial aneurysm: Preliminary results

Abstract

Aim: Brain aneurysm is a balloon shaped dilatation of brain vessels as a result of attenuation of the vessel walls. The aim of this study was to evaluate the relationship between blood flow velocities in the right and left arterial vessels in an unruptured aneurysm and healthy group, and to investigate whether this analysis can help early diagnosis of aneurysm.

Methods: Four aneurysm patients (four female, mean age 57.25 ± 0.75 years) and four healthy subjects (two female, 2 male male, mean age 36.35 ± 6.19 years) were included in the study. Blood flow velocity values ​​of right and left internal carotid arteries, vertebral artery and right and left internal jugular veins were obtained during a cardiac cycle with phase contrast technique. Spearman's correlation analysis was applied to flow velocity values. Statistically significant blood flow similarities between right and left brain were investigated.

Results: In the aneurysm group, there was a significant difference between right and left cervical arterial blood flow velocity values (p=0.001). Spearman correlation coefficient values between right and left arterial blood flow velocity values and right and left side arteriovenous blood flow velocity values were lower in the aneurysm group compared to the control group however, there was no statistical significance (p≥0.05 for all).

Conclusion:  The difference between the right and left arterial blood flow velocities obtained in the aneurysm group and the low correlation values may be useful in early diagnosis of aneurysm. 

Keywords

• Cerebral aneurysm,Spearman’s correlation analysis,blood flow velocity,phase contrast MR

Tek taraflı intrakranial anevrizmalı hastalarda servikal kan akış hızı değerleri: Ön sonuçlar

Öz

Amaç: Beyin anevrizması damar çeperlerindeki zayıflama sonucu beyin damarlarında oluşan balon şeklinde genişlemedir. Bu araştırmanın amacı, kanamasız anevrizmalı ve sağlıklı grupta sağ ve sol arteriyel damarlardaki kan akış hızlarını değerlendirmek ve bu analizin anevrizma ön tanısına yardımcı olup olamayacağını araştırmaktır.

Yöntemler: Araştırmaya dört anevrizma hastası (dört kadın, ortalama yaş 57,25 ± 0,75) ve dört sağlıklı denek  (iki kadın, iki erkek, ortalama yaş 36,35 ± 6,19) dahil edildi. Sağ ve sol iç karotis arter, vertebral arter ve sağ ve sol iç jugular ven kan akış hızı değerleri faz kontrast tekniği ile bir kardiyak döngü boyunca elde edildi. Spearman’ın ilişki analizi akış hızı değerlerine uygulandı. Beyinin sağı ve solu arasındaki istatistiksel olarak anlamlı kan akış benzerlikleri araştırıldı.

Bulgular: Anevrizma grubunda,  sağ ve sol taraf servikal arteriyel kan akış hızı değerleri arasında anlamlı fark bulundu (p=0,001). Sağ ve sol arteriyel kan akış hızı değerleri arasındaki ve sağ ve sol taraf arteriyovenöz kan akış hızı değerleri arasındaki Spearman ilişki katsayı değerleri anevrizma grubunda kontrol grubuna göre düşüktü, ancak istatistiksel anlamlılık yoktu (hepsi  için p≥0,05).

Sonuç: Bu ön araştırmanın sonuçları, anevrizma grubunda elde edilen sağ ve sol arteriyel kan akış hızları arasındaki belirgin farkın ve düşük ilişki değerlerinin anevrizma tanısında faydalı olabileceğini düşündürdü. 

Anahtar Kelimeler

• Beyin anevrizması,Spearman ilişki analizi,kan akış hızı,faz kontrast MR

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