Aims: This study aimed to determine the factors predicting the development of hepatorenal syndrome (HRS) in cirrhotic patients presenting with acute kidney injury (AKI).
Methods: We retrospectively analyzed 263 cirrhotic patients diagnosed with AKI between September 2022 and March 2024. Demographic characteristics, clinical findings, and laboratory results were analyzed. We diagnosed HRS using the 2019 International Club of Ascites criteria. We used bivariate and multivariate logistic regression models in our statistical analysis.
Results: HRS developed in 31 patients (11.8%). MELD-Na scores were significantly higher in the HRS group (28 vs. 18, p<0.05). In multivariate analysis, independent predictors of HRS development were history of ascites (OR 5.8, 95% CI 2.6-13.0), serum creatinine >2.5 mg/dl (OR 2.5, 95% CI 1.2-5.5), albumin <2 g/dl (OR 3.9, 95% CI 1.1-13.5), bilirubin >2 mg/dl (OR 7.9, 95% CI 3.7-17.0), and presence of spontaneous bacterial peritonitis (OR 5.5, 95% CI 1.4-12.2). Hemodialysis requirement (61.3% vs. 8.6%, p<0.05) and mortality rates (45.2% vs. 6.0%, p<0.05) were significantly higher in the HRS group.
Conclusion: This study revealed important factors predicting the development of HRS in cirrhotic patients presenting with AKI. These findings may help clinicians to identify high-risk patients early and develop appropriate treatment strategies.
Primary Language | English |
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Subjects | Gastroenterology and Hepatology |
Journal Section | Research Articles |
Authors | |
Publication Date | January 10, 2025 |
Submission Date | July 30, 2024 |
Acceptance Date | December 2, 2024 |
Published in Issue | Year 2025 |
Üniversitelerarası Kurul (ÜAK) Eşdeğerliği: Ulakbim TR Dizin'de olan dergilerde yayımlanan makale [10 PUAN] ve 1a, b, c hariç uluslararası indekslerde (1d) olan dergilerde yayımlanan makale [5 PUAN]
- Dahil olduğumuz İndeksler (Dizinler) ve Platformlar sayfanın en altındadır.
Not: Dergimiz WOS indeksli değildir ve bu nedenle Q olarak sınıflandırılmamaktadır.
Yüksek Öğretim Kurumu (YÖK) kriterlerine göre yağmacı/şüpheli dergiler hakkındaki kararları ile yazar aydınlatma metni ve dergi ücretlendirme politikasını tarayıcınızdan indirebilirsiniz. https://dergipark.org.tr/tr/journal/3449/page/10809/update
Dergi Dizin ve Platformları
TR Dizin ULAKBİM, Google Scholar, Crossref, Worldcat (OCLC), DRJI, EuroPub, OpenAIRE, Turkiye Citation Index, Turk Medline, ROAD, ICI World of Journal's, Index Copernicus, ASOS Index, General Impact Factor, Scilit.