Monocyte/HDL ratio in women with polycystic ovary syndrome and healthy controls

Abstract

Aim: to examine and compare various variables, especially monocyte / high-density lipoprotein cholesterol (HDL) ratio (MHR), in women with Polycystic Ovary Syndrome (PCOS) and healthy controls. Materials and Methods: Data of patients who applied to Adana City Training & Research Hospital Gynecology and Obstetrics Outpatient Clinic were analyzed retrospectively from the hospital database. The records of a total of 259 cases, including 194 with PCOS and 65 without PCOS who had normal menstrual cycles between the ages of 18-38, were examined. Results: When compared with the control group, the overweight/obese PCOS group was found to have higher triglyceride value. Age and neutrophil values were significantly higher, whereas red blood cell distribution width was lower in the control group compared to both PCOS groups. Weight and BMI values were significantly different for all three groups. The HDL value was detected to be significantly higher in the normoweight PCOS group compared to the overweight/obese PCOS group. Total cholesterol value was significantly higher in the overweight/obese PCOS group compared to the normoweight PCOS group. The MHR values was found to be similar in all groups. Conclusions: In previous studies, although the importance of MHR was emphasized in predicting and preventing obesity in PCOS cases, it was concluded that this relationship was not significant in our study. Although the present study has various limitations, there are few studies on this subject and our findings represent an important difference from available results, suggesting the presence of underlying variations that necessitate further studies on this subject.

Keywords

• Polycystic Ovary Syndrome
• Obesity
• Inflammation
• Monocyte
• High-Density Lipoprotein

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