Case Report
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Year 2021, , 69 - 71, 22.01.2021
https://doi.org/10.38053/acmj.865020

Abstract

References

  • Casqueiro J, Casqueiro J, Alves C. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab 2012; 16: 27–36.
  • Bertoni, Alain G., Sharon Saydah, and Frederick L. Brancati. Diabetes and the risk of infection-related mortality in the US. Diabetes Care 2001; 24: 1044-9.
  • Muller LM, Gorter KJ, Hak E, et al. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281–8.
  • Cockram CS, Lee N. Diabetes and Infections. In: Holt R, Cockram C, Flyvbjerg A, Goldstein B, eds. Textbook of Diabetes, 4th ed. Chichester: Wiley-Blackwell, 2010.
  • Pearson-Stuttard J, Blundell S, Harris T, Cook DG, Critchley J. Diabetes and infection: assessing the association with glycaemic control in population-based studies. Lancet Diabetes Endocrinol 2016; 4: 148-58.
  • Shah BR, Hux JE: Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care 2003; 26: 510-13
  • Muller LM, Gorter KJ, Hak E, Goudzwaard WL, Schellevis FG, Hoepelman AI, Rutten GE: Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281-8
  • Saeed NK, Al-Biltagi M. Diabetes and Infections: Which is the Fuel?. 2014.
  • Cooke FJ. Infections in people with diabetes. Medicine 2015; 43: 41-3.
  • Geerlings SE, Hoepelman AI. Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol 1999; 26: 256-65.
  • Muller LM, Gorter KJ, Hak E, et al. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281-8.
  • Price CL, Al Hassi HO, English NR, Blakemore AI, Stagg AJ, Knight SC. Methylglyoxal modulates immune responses: relevance to diabetes. J Cell Mol Med 2010; 14: 1806-15.
  • Kubota M, Kanno T, Nishiyama R, Okada T, Higashi Y, Yamada H. A case of abscess of corpus spongiosum associated with rectal cancer. Hinyokika Kiyo 2013; 59: 539-43.

Corpus spongiosum abscess presented as new-onset diabetes in an adult patient: a case presentation

Year 2021, , 69 - 71, 22.01.2021
https://doi.org/10.38053/acmj.865020

Abstract

Rare infections, known as signal infections might be pathognomonic for patients with diabetes mellitus. A 55-year-old man without a significant medical history was admitted to our hospital with polyuria, polydipsia, dysuria, fever, chills and weight loss for the last month. A laboratory investigation showed leukocytosis and, elevated levels of C-reactive protein, sedimentation rate, blood glucose, and HbA1c. The patient was hospitalized in the internal medicine service and started intensive insulin therapy with intravenous saline infusion. The patient's fever and chills were not improved despite ceftriaxone treatment for three days. Ceftriaxone-resistant, imipenem-sensitive E. coli was grown in the blood cultures, so ceftriaxone was stopped and imipenem plus cilastatin combination was started. Detailed physical examination of the patient for fever etiology showed severe swelling in the perineal region. Superficial and scrotal ultrasonography and then pelvic magnetic resonance imaging revealed corpus spongiosum abscess. The perineal region was punctured and numerous Gram-negative bacilli and polymorphonuclear leukocytes were seen in the gram stain. Drainage catheter was inserted into the corpus spongiosum. Blood sugar levels were regulated and the patient was discharged after the antibiotic treatment was completed. As in our case, signal infections should be kept in mind especially in patients admitted with new onset of diabetes mellitus and persistent fever. A detailed physical examination should be performed in these patients and atypical areas like perineum should be carefully examined.

References

  • Casqueiro J, Casqueiro J, Alves C. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab 2012; 16: 27–36.
  • Bertoni, Alain G., Sharon Saydah, and Frederick L. Brancati. Diabetes and the risk of infection-related mortality in the US. Diabetes Care 2001; 24: 1044-9.
  • Muller LM, Gorter KJ, Hak E, et al. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281–8.
  • Cockram CS, Lee N. Diabetes and Infections. In: Holt R, Cockram C, Flyvbjerg A, Goldstein B, eds. Textbook of Diabetes, 4th ed. Chichester: Wiley-Blackwell, 2010.
  • Pearson-Stuttard J, Blundell S, Harris T, Cook DG, Critchley J. Diabetes and infection: assessing the association with glycaemic control in population-based studies. Lancet Diabetes Endocrinol 2016; 4: 148-58.
  • Shah BR, Hux JE: Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care 2003; 26: 510-13
  • Muller LM, Gorter KJ, Hak E, Goudzwaard WL, Schellevis FG, Hoepelman AI, Rutten GE: Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281-8
  • Saeed NK, Al-Biltagi M. Diabetes and Infections: Which is the Fuel?. 2014.
  • Cooke FJ. Infections in people with diabetes. Medicine 2015; 43: 41-3.
  • Geerlings SE, Hoepelman AI. Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol 1999; 26: 256-65.
  • Muller LM, Gorter KJ, Hak E, et al. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 2005; 41: 281-8.
  • Price CL, Al Hassi HO, English NR, Blakemore AI, Stagg AJ, Knight SC. Methylglyoxal modulates immune responses: relevance to diabetes. J Cell Mol Med 2010; 14: 1806-15.
  • Kubota M, Kanno T, Nishiyama R, Okada T, Higashi Y, Yamada H. A case of abscess of corpus spongiosum associated with rectal cancer. Hinyokika Kiyo 2013; 59: 539-43.
There are 13 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Serhat Celik This is me 0000-0002-1052-9800

Sanem Öztekin This is me 0000-0001-7736-2681

Muhammed Kizilgul 0000-0002-8468-9196

Publication Date January 22, 2021
Published in Issue Year 2021

Cite

AMA Celik S, Öztekin S, Kizilgul M. Corpus spongiosum abscess presented as new-onset diabetes in an adult patient: a case presentation. Anatolian Curr Med J / ACMJ / acmj. January 2021;3(1):69-71. doi:10.38053/acmj.865020

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