Investigation of the treatment and follow-up approaches of pregnant with asthma

Year 2024, Volume: 6 Issue: 1, 23 - 28, 15.01.2024

Gülhan Ayhan Albayrak , Mustafa İlteriş Bardakçı

https://doi.org/10.38053/acmj.1359413

Abstract

Aims: Uncontrolled asthma during pregnancy can lead to complications for both the mother and the fetus. In this study; It was aimed to evaluate the follow-up and treatment of pregnant women with asthma, their knowledge about asthma triggers, their use of inhaler therapy, and their compliance with pulmonologist controls for asthma.
Methods: In this study; 64 pregnant patients with asthma who applied to our clinic between 01.01.2022 and 31.07.2022 were reviewed. Demographic patients (mean age, age groups, smoking history, comorbidities), recommended treatment information, and birth information, whether they used asthma treatment or not, were recorded and evaluated according to patient groups.
Results: There was a statistically significant difference between drug use during pregnancy according to the age groups of pregnant women with asthma (Chi-square test; χ²=6.684; p=0.035). As the age of the pregnant women increased, the rate of drug use during the pregnancy increased, and there was a correlation between drug use during pregnancy and whether the patients were regularly checked by a pulmonologist (Chi-square test; χ²=12.835; p=0.0001). While 68% of those who were not under the control of a pulmonologist did not use medication, 60.8% of those under the control of a pulmonologist used medication during their pregnancy.
Conclusion: Pregnant women with asthma must be followed by a gynecologist and a pulmonologist. Using inhaler therapy in asthma treatment in pregnant women can keep asthma under control and reduce the number and severity of exacerbations.

Keywords

Pregnancy, asthma therapy, inhaler therapy, asthma triggers

Ethical Statement

Ethical Declaration All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008. Ethics committee approval has been granted from our institution. As this was a retrospective research no informed consent has been obtained from participants.

Supporting Institution

There is no specific funding related to this research.

References

• Namazy JA, Schatz M. Chronic management of asthma during pregnancy. Immunol Allergy Clin North Am. 2023;43(1):65-85. doi: 10.1016/j.iac.2022.09.001
• Robijn AL, Bokern MP, Jensen ME, Barker D, Baines KJ, Murphy VE. Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis. Eur Respir Rev. 2022;31(164):220039. doi: 10.1183/16000617.0039-2022
• Gade EJ, Tidemandsen C, Hansen AV, Ulrik CS, Backer V. Challenges in the successful management of asthma during conception, pregnancy and delivery. Breathe. 2022;18(2):220013. doi: 10.1183/20734735.0013-2022
• Grzeskowiak LE, Smith B, Roy A, et al.. Patterns, predictors and outcomes of asthma control and exacerbations during pregnancy: a prospective cohort study. ERJ Open Res. 2016;2(1):00054-2015. doi: 10.1183/23120541.00054-2015
• Gandler A, Schulman ES, Yoo EJ. Improving asthma outcomes during pregnancy in underserved communities. Immunol Allergy Clin North Am. 2023;43(1):199-208. doi: 10.1016/j.iac.2022.07.002
• Vieira AC, Pité H, Morais-Almeida M. Asthma and pregnancy in the 2020 decade: still a matter of concern. J Matern Fetal Neonatal Med. 2022;35(25):6498-6504. doi: 10.1080/14767058.2021.1916462
• Bokern MP, Robijn AL, Jensen ME, Barker D, Baines KJ, Murphy VE. Risk factors for asthma exacerbation during pregnancy: protocol for a systematic review and meta-analysis. Syst Rev. 2022;11(1):115. doi: 10.1186/s13643-022-01975-8
• Carvalho-Pinto RM, Cançado JED, Caetano LSB, et al. Asthma and pregnancy. Rev Assoc Med Bras. 2023;69(Suppl 1):e2023S123
• Kwah JH, Stevens WW. Asthma and allergies in pregnancy. Allergy Asthma Proc. 2019;40(6):414-417. doi: 10.2500/aap.2019.40.4260
• Murphy VE, Wang G, Namazy JA, et al. The risk of congenital malformations, perinatal mortality, and neonatal hospitalization among pregnant women with asthma: a systematic review and meta-analysis. BJOG. 2013;120(7):812-822
• Blais L, Kettani FZ, Forget A. Relationship between maternal asthma, its severity and control, and abortion. Hum Reprod. 2013;28(4):908-915
• Baarnes CB, Hansen AV, Ulrik CS. Enrolment in an asthma management program during pregnancy and adherence with inhaled corticosteroids: the ‘management of asthma during pregnancy’ program. Respiration. 2016;92(1):9-15
• Jana N, Vasishta K, Saha SC, Khunnu B. Effect of bronchial asthma on the course of pregnancy, labor and perinatal outcome. J Obstet Gynecol. 1995;21(3):227-232
• Vieira AC, Pité H, Morais-Almeida M. Asthma and pregnancy in the 2020 decade: still a matter of concern. J Matern Fetal Neonatal Med. 2022;35(25):6498-6504. doi: 10.1080/14767058.2021.1916462
• Murphy VE. Asthma in pregnancy - management, maternal co-morbidities, and long-term health. Best Pract Res Clin Obstet Gynaecol. 2022;85(Pt A):45-56. doi: 10.1016/j.bpobgyn.2022.06.005
• Bravo-Solarte DC, Garcia-Guaqueta DP, Chiarella SE. Asthma in pregnancy. Allergy Asthma Proc. 2023;44(1):24-34. doi: 10.2500/aap.2023.44.220077
• Murphy VE, Gibson PG, Schatz M. Managing asthma during pregnancy and the postpartum period. J Allergy Clin Immunol Pract. 2023;11(12):3585-3594. doi: 10.1016/j.jaip.2023.07.020
• Huang J, Namazy J. Asthma in pregnancy. JAMA. 2023;329(22): 1981-1982. doi: 10.1001/jama.2023.5588