Odontogenic and non-odondogenic cysts in the jaws: a retrospective analysis

Year 2025, Volume: 7 Issue: 1, 54 - 59, 10.01.2025

Elif Çoban , Berkan Altay , Allahverdi Chodarov

https://doi.org/10.38053/acmj.1592255

Abstract

Aims: This study aims to retrospectively analyze the demographic, clinical, and radiological characteristics of jaw cysts and evaluate the implications of these findings for accurate diagnosis, effective treatment planning, and the prevention of potential complications.
Methods: This retrospective cross-sectional study was conducted at the Kırıkkale University Oral and Maxillofacial Surgery Clinic between April 2023 and May 2024. A total of 178 patients, histopathologically diagnosed with jaw cysts, were included. Data on demographic factors such as age and gender, as well as clinical and radiological features of the cysts, were collected and analyzed.
Results: The mean age of the patients was 48.52±16.56 years, with 56.74% of the cohort being male and 43.25% female. The distribution of lesions was as follows: 53.93% in the mandible, 43.82% in the maxilla, and 2.25% in both jaws. Radiologically, 79.77% of the lesions were radiolucent, while 20.22% exhibited a mixed radiological pattern. Clinically, 86.52% of the lesions were asymptomatic, while 13.48% were symptomatic. The most prevalent cyst types identified were radicular cysts (35.4%), dentigerous cysts (19.1%), and keratocysts (19.1%).
Conclusion: A comprehensive analysis of the demographic and radiological characteristics of jaw cysts plays a pivotal role in achieving precise diagnoses and devising effective treatment strategies. The present study shows that radicular cysts are the most common type, which is consistent with previous studies. However, the findings indicate a lower prevalence of radicular cysts compared to other studies focusing on cystic lesions. Moreover, this study reports higher prevalence rates for dentigerous cysts and keratocysts compared to certain other studies. These findings emphasize the importance of accounting for individual and population-based variability when diagnosing and managing jaw cysts.

Keywords

Jaw cysts, odontogenic cysts, non-odontogenic cysts, retrospective analysis

References

• Rajendra Santosh AB. Odontogenic cysts. Dent Clin North Am. 2020; 64(1):105-119. doi:10.1016/j.cden.2019.08.002
• Johnson NR, Gannon OM, Savage NW, Batstone MD. Frequency of odontogenic cysts and tumors: a systematic review. J Investig Clin Dent. 2014;5(1):9-14. doi:10.1111/jicd.12044
• Speight PM, Takata T. New tumour entities in the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumours. Virchows Arch. 2018; 472(3):331-339. doi:10.1007/s00428-017-2182-3
• Sivapathasundharam B, Biswas PG, Preethi S. The World Health Organization classification of odontogenic and maxillofacial bone tumors: an appraisal. J Oral Maxillofac Pathol. 2019;23(2):178-186. doi: 10.4103/jomfp.JOMFP_211_19
• Demirkol M, Ege B, Yanik S, Aras MH, Ay S. Clinicopathological study of jaw cysts in southeast region of Turkey. Eur J Dent. 2014;8(1):107-111. doi:10.4103/1305-7456.126260
• Lo Muzio L, Mascitti M, Santarelli A, et al. Cystic lesions of the jaws: a retrospective clinicopathologic study of 2030 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124(2):128-138. doi:10.1016/j.oooo.2017.04. 006
• Tekkesin MS, Olgac V, Aksakalli N, Alatli C. Odontogenic and nonodontogenic cysts in Istanbul: analysis of 5088 cases. Head Neck. 2012;34(6):852-855. doi:10.1002/hed.21820
• Tamiolakis P, Thermos G, Tosios KI, Sklavounou-Andrikopoulou A. Demographic and clinical characteristics of 5294 jaw cysts: a retrospective study of 38 years. Head Neck Pathol. 2019;13(4):587-596. doi:10.1007/s12105-019-01011-7
• Hupp James R, Ellis Edward, Tucker Myron R., eds. Contemporary oral and maxillofacial surgery. In: contemporary oral and maxillofacial surgery. 5th. Elsevier; 2019:478-488.
• Scholl RJ, Kellett HM, Neumann DP, Lurie AG. Cysts and cystic lesions of the mandible: clinical and radiologic-histopathologic review. Radiographics. 1999;19(5):1107-1124. doi:10.1148/radiographics.19.5. g99se021107
• Oner B, Donmez Semiz H. Retrospective evaluation of odontogenic and nonodontogenic cysts in the jaws in the series of 147 cases. Oral Health Dental Sci. 2020;4(1):1-9. doi:10.33425/2639-9490.1065
• Du C, Wang Z, Lan D, et al. Clinical analysis of 1,038 cases of odontogenic jawbone cysts. BMC Oral Health. 2024;24(1):1387. doi:10.1186/s12903-024-05167-9
• Baştoklu S, Çelik M, Karabağlı P. Çene kistleri: Konya bölgesinde 274 olguda klinikopatolojik ve retrospektif bir çalışma. Genel Tıp Dergisi. 2016;26(1):8-8. doi:10.15321/GenelTipDer.20162618131
• Gnepp DR. Diagnostic surgical pathology of the head and neck. 2nd Edition, Saunders/Elsevier, Philadelphia; 2009.
• Nakamura T, Ishida J, Nakano Y, et al. A study of cysts in the oral region. Cysts of the jaw. J Nihon Univ Sch Dent. 1995;37(1):33-40. doi:10.2334/josnusd1959.37.33
• Mutio J, Dimba E, Sarna K, et al. Changing trends of odontogenic cysts and tumors in Kenya: a 20-year retrospective analysis. Cureus. 2024; 16(9):e70471. doi:10.7759/cureus.70471
• Bilodeau EA, Collins BM. Odontogenic cysts and neoplasms. Surg Pathol Clin. 2017;10(1):177-222. doi:10.1016/j.path.2016.10.006
• Jones A V, Franklin CD. An analysis of oral and maxillofacial pathology found in adults over a 30-year period. J Oral Pathol Med. 2006;35(7):392-401. doi:10.1111/j.1600-0714.2006.00451.x
• Narang RS, Manchanda AS, Arora P, Randhawa K. Dentigerous cyst of inflammatory origin-a diagnostic dilemma. Ann Diagn Pathol. 2012; 16(2):119-123. doi:10.1016/j.anndiagpath.2011.07.004