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FAKOEMÜLSİFİKASYONUN PREOPERATİF VE POSTOPERATİF YÖNETİMİNDE POLİVİNİL ALKOL VE POVİDON KULLANIMI

Year 2025, Volume: 6 Issue: 3, 173 - 181, 28.09.2025
https://doi.org/10.47482/acmr.1629439

Abstract

Amaç: Fakoemülsifikasyon uygulanan hastalarda perioperatif dönemde düzenli polivinil alkol ve povidon göz damlası uygulamasının fakoemülsifikasyona sekonder gelişen kuru göz sendromunun belirti ve semptomları üzerine etkisini araştırmaktır.
Gereç ve Yöntem: Senil katarakt nedeniyle fakoemülsifikasyon uygulanan hastalar iki ayrı grupta incelendi: Topikal moksifloksasin, prednizolon ve polivinil alkol ve povidon göz damlası ile takip edilen hastalar Grup I (n = 52 hasta), topikal moksifloksasin ve prednizolon ile takip edilen hastalar Grup II (n = 52 hasta) olarak isimlendirildi. Gözyaşı Kırılma Zamanı, Schirmer I, Oxford derecelendirme ölçeği ve Oküler Yüzey Hastalık İndeksi anketi tüm hastalara ameliyat öncesi ve ameliyat sonrası 1. ve 3. ayda uygulandı.
Bulgular: Çalışmadan elde edilen sonuçlara göre veriler değişmektedir. Çalışmaya dahil edilen hastaların (n=104 hasta) %50’si kadın, %50’si erkek olup yaş ortalamaları 59.83 ± 5.33 idi. Grup I’de postoperatif dönemde TBUT ve Schirmer I değerlerinde artış (p<0.05) görülürken, Oxford derecelendirme skalasında azalma (p<0.05) görüldü. Grup II’de ise postoperatif dönemde TBUT azalırken (p<0.05) Oxford derecelendirme skalasında artış (p<0.05) görüldü. Subjektif değerlendirmede kullanılan OSDI anketinin sonuçlarına göre her iki grupta da postoperatif iyileşme görüldü (p<0.05).
Sonuç: Fakoemülsifikasyon cerrahisinin perioperatif dönemi göz önüne alındığında polivinil alkol ve povidon göz damlası kullanımının kuru göz bulgularına olumlu katkıda bulunduğu görüldü. Ayrıca, ameliyat öncesi suni gözyaşlarının kullanımı, enfeksiyon riskini azaltan ve böylece ön segmentin sağlıklı homeostazını koruyan ameliyat sonrası kuru göz sendromunun önlenmesi için son derece önemlidir.

References

  • Duan ZH, Tang YF. The clinical effects of sodium hyaluronate, polyethylene glycol, and dextran-70 eye drops in relieving dry eye after phacoemulsification. Medicine (Baltimore). 2021;100(25):e26358.
  • Lu Q, Lu Y, Zhu X. Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021;8:649030.
  • Naderi K, Gormley J, O’Brart D. Cataract surgery and dry eye disease: A review. Eur J Ophthalmol. 2020;30(5):840-55.
  • Nibandhe AS, Donthineni PR. Understanding and Optimizing Ocular Biometry for Cataract Surgery in Dry Eye Disease: A Review. Semin Ophthalmol. 2023;38(1):24-30.
  • Boulter T, Bernhisel A, Mamalis C, Zaugg B, Barlow WR, Olson RJ, et al. Phacoemulsification in review: Optimization of cataract removal in an in vitro setting. Surv Ophthalmol. 2019;64(6):868-75.
  • Shi DS, Jensen JD, Kramer GD, Zaugg B, Stagg BC, Pettey JH, et al. Comparison of Vacuum and Aspiration on Phacoemulsification Efficiency and Chatter Using a Monitored Forced Infusion System. Am J Ophthalmol. 2016;169:162-7.
  • Mehuys E, Delaey C, Christiaens T, Van Bortel L, Van Tongelen I, Remon JP, et al. Eye drop technique and patient-reported problems in a real-world population of eye drop users. Eye (Lond). 2020;34(8):1392-8.
  • Lu H, Guan Y, Su Y, Nan N, Yuan Y. Effect of sodium hyaluronate eye drops combined with tobramycin, dexamethasone and pranoprofen eye drops in the treatment of dry eye after phacoemulsification. Indian J Ophthalmol. 2022;70(12):4319-24.
  • Amer AA, Abu El Wafa Ali EG, Hamed MA, Gad Elkareem AM, Ahmed Sinjab AA, Awny I. Efficacy of Adding Sodium Hyaluronate Eye Drops to Tobramycin and Dexamethasone in the Treatment of Post-Cataract Surgery Dry Eye Disease: A Retrospective Analysis and Prospective Questionnaire Assessment. Clin Ophthalmol. 2024;18:613-21.
  • Son HS, Yildirim TM, Khoramnia R, Poompokawat P, Knorz MC, Auffarth GU. Semi-fluorinated Alkane Eye Drops Reduce Signs and Symptoms of Evaporative Dry Eye Disease After Cataract Surgery. J Refract Surg. 2020;36(7):474-80.
  • Chen N, Zhang JS, Zhang TX, Shao YS, Zhang F. The Effect of Sodium Hyaluronate on the Corneal Biomechanics of Patients with Cataract and Dry Eye Before Operation. Int J Gen Med. 2021;14:2377-84.
  • Cagini C, Torroni G, Mariniello M, Di Lascio G, Martone G, Balestrazzi A. Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders. Int Ophthalmol. 2021;41(9):3065-71.
  • Park Y, Hwang HB, Kim HS. Observation of Influence of Cataract Surgery on the Ocular Surface. PLoS One. 2016;11(10):e0152460.
  • Labetoulle M, Benitez-Del-Castillo JM, Barabino S, Herrero Vanrell R, Daull P, Garrigue JS, et al. Artificial Tears: Biological Role of Their Ingredients in the Management of Dry Eye Disease. Int J Mol Sci. 2022;23(5).
  • Xiao W, Huang P. Effects of the preoperative use of artificial tears combined with recombinant bovine basic fibroblast growth factor on cataract patients complicated with dry eyes. Arq Bras Oftalmol. 2022;87(2):0539.
  • Mason L, Jafri S, Dortonne I, Sheppard JD, Jr. Emerging therapies for dry eye disease. Expert Opin Emerg Drugs. 2021;26(4):401-13.
  • Kam KW, Di Zazzo A, De Gregorio C, Narang P, Jhanji V, Basu S. A review on drug-induced dry eye disease. Indian J Ophthalmol. 2023;71(4):1263-9.
  • Khoo P, Ooi KG, Watson S. Effectiveness of pharmaceutical interventions for meibomian gland dysfunction: An evidence-based review of clinical trials. Clin Exp Ophthalmol. 2019;47(5):658-68.
  • Noyman DBE, Chan CC, Mimouni M, Safir M. The Efficacy and Safety of Standard versus Soft Topical Steroids after Cataract Surgery: A Systematic Review and Meta-analysis. Ophthalmology. 2024;131(5):595-610.

The Use of Polyvinyl Alcohol & Povidone During The Preoperative and Postoperative Management of Phacoemulsification

Year 2025, Volume: 6 Issue: 3, 173 - 181, 28.09.2025
https://doi.org/10.47482/acmr.1629439

Abstract

Background: To investigate the effect of regular application of polyvinyl alcohol & povidone eye drops during the perioperative period in patients undergoing phacoemulsification on the signs and symptoms of dry eye syndrome developing secondary to phacoemulsification.
Methods: Patients who underwent phacoemulsification due to senile cataract were examined in two separate groups: Patients followed with topical moxifloxacin, prednisolone and polyvinyl alcohol & povidone eye drops, Group I , patients followed with topical moxifloxacin and prednisolone, Group II was separated as.
Results: According to the results obtained from the study, the data vary. Of the patients included in the study (n = 104 patients), 50% were female and 50% were male, and their average age was 59.83 ± 5.33. In Group I, there was an increase in TBUT and Schirmer I values in the postoperative period (p < 0.05), while there was a decrease in the Oxford grading scale (p < 0.05). On the other hand, in Group II, while TBUT decreased in the postoperative period (p < 0.05), an increase in Oxford grading scale was detected (p < 0.05).
Conclusion: Considering the perioperative period of phacoemulsification surgery, it was observed that the use of polyvinyl alcohol & povidone eye drops contributed positively to dry eye findings. Moreover, the use of preoperative artificial tears is extremely important for the prevention of postoperative dry eye syndrome, which reduces the risk of infection and thus maintaining healthy homeostasis of the anterior segment.

Ethical Statement

The Medical Ethics Association of Nigde Omer Halisdemir University approved this study (No: 2022/58). The procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 2000.

Supporting Institution

This study has received no funding, granting or sponsorship.

Thanks

I would like to thank Dr. Necmettin Kurtul for the precious help during the process of language revision and editing.

References

  • Duan ZH, Tang YF. The clinical effects of sodium hyaluronate, polyethylene glycol, and dextran-70 eye drops in relieving dry eye after phacoemulsification. Medicine (Baltimore). 2021;100(25):e26358.
  • Lu Q, Lu Y, Zhu X. Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021;8:649030.
  • Naderi K, Gormley J, O’Brart D. Cataract surgery and dry eye disease: A review. Eur J Ophthalmol. 2020;30(5):840-55.
  • Nibandhe AS, Donthineni PR. Understanding and Optimizing Ocular Biometry for Cataract Surgery in Dry Eye Disease: A Review. Semin Ophthalmol. 2023;38(1):24-30.
  • Boulter T, Bernhisel A, Mamalis C, Zaugg B, Barlow WR, Olson RJ, et al. Phacoemulsification in review: Optimization of cataract removal in an in vitro setting. Surv Ophthalmol. 2019;64(6):868-75.
  • Shi DS, Jensen JD, Kramer GD, Zaugg B, Stagg BC, Pettey JH, et al. Comparison of Vacuum and Aspiration on Phacoemulsification Efficiency and Chatter Using a Monitored Forced Infusion System. Am J Ophthalmol. 2016;169:162-7.
  • Mehuys E, Delaey C, Christiaens T, Van Bortel L, Van Tongelen I, Remon JP, et al. Eye drop technique and patient-reported problems in a real-world population of eye drop users. Eye (Lond). 2020;34(8):1392-8.
  • Lu H, Guan Y, Su Y, Nan N, Yuan Y. Effect of sodium hyaluronate eye drops combined with tobramycin, dexamethasone and pranoprofen eye drops in the treatment of dry eye after phacoemulsification. Indian J Ophthalmol. 2022;70(12):4319-24.
  • Amer AA, Abu El Wafa Ali EG, Hamed MA, Gad Elkareem AM, Ahmed Sinjab AA, Awny I. Efficacy of Adding Sodium Hyaluronate Eye Drops to Tobramycin and Dexamethasone in the Treatment of Post-Cataract Surgery Dry Eye Disease: A Retrospective Analysis and Prospective Questionnaire Assessment. Clin Ophthalmol. 2024;18:613-21.
  • Son HS, Yildirim TM, Khoramnia R, Poompokawat P, Knorz MC, Auffarth GU. Semi-fluorinated Alkane Eye Drops Reduce Signs and Symptoms of Evaporative Dry Eye Disease After Cataract Surgery. J Refract Surg. 2020;36(7):474-80.
  • Chen N, Zhang JS, Zhang TX, Shao YS, Zhang F. The Effect of Sodium Hyaluronate on the Corneal Biomechanics of Patients with Cataract and Dry Eye Before Operation. Int J Gen Med. 2021;14:2377-84.
  • Cagini C, Torroni G, Mariniello M, Di Lascio G, Martone G, Balestrazzi A. Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders. Int Ophthalmol. 2021;41(9):3065-71.
  • Park Y, Hwang HB, Kim HS. Observation of Influence of Cataract Surgery on the Ocular Surface. PLoS One. 2016;11(10):e0152460.
  • Labetoulle M, Benitez-Del-Castillo JM, Barabino S, Herrero Vanrell R, Daull P, Garrigue JS, et al. Artificial Tears: Biological Role of Their Ingredients in the Management of Dry Eye Disease. Int J Mol Sci. 2022;23(5).
  • Xiao W, Huang P. Effects of the preoperative use of artificial tears combined with recombinant bovine basic fibroblast growth factor on cataract patients complicated with dry eyes. Arq Bras Oftalmol. 2022;87(2):0539.
  • Mason L, Jafri S, Dortonne I, Sheppard JD, Jr. Emerging therapies for dry eye disease. Expert Opin Emerg Drugs. 2021;26(4):401-13.
  • Kam KW, Di Zazzo A, De Gregorio C, Narang P, Jhanji V, Basu S. A review on drug-induced dry eye disease. Indian J Ophthalmol. 2023;71(4):1263-9.
  • Khoo P, Ooi KG, Watson S. Effectiveness of pharmaceutical interventions for meibomian gland dysfunction: An evidence-based review of clinical trials. Clin Exp Ophthalmol. 2019;47(5):658-68.
  • Noyman DBE, Chan CC, Mimouni M, Safir M. The Efficacy and Safety of Standard versus Soft Topical Steroids after Cataract Surgery: A Systematic Review and Meta-analysis. Ophthalmology. 2024;131(5):595-610.
There are 19 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section ORIGINAL ARTICLE
Authors

Ceren Turkoglu 0000-0001-7573-877X

Publication Date September 28, 2025
Submission Date January 29, 2025
Acceptance Date May 2, 2025
Published in Issue Year 2025 Volume: 6 Issue: 3

Cite

APA Turkoglu, C. (2025). The Use of Polyvinyl Alcohol & Povidone During The Preoperative and Postoperative Management of Phacoemulsification. Archives of Current Medical Research, 6(3), 173-181. https://doi.org/10.47482/acmr.1629439

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