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Urethroplasty in Rabbit Model With Tutoplast Tube

Year 1996, Volume: 1 Issue: 1, 22 - 24, 30.11.1996

Abstract



Objective: Genital
and perineal injuries are curently frequently encountered results of trauma in
children. These injuries which usually involve the urethra, lead to
complications such as incontinence and urinary obstruction. In urethral
obstruction, while dilatation with internal and external urethrotomy,
urethrotomy and dilatation together with steroid injections may produce
temporary improvement in some cases, uroplasty is indicated in the majority of
patients various non biological materials have been used tubal and patch forms
to repair urethral lesions. But it has shown that the tubes are usually covered
with urinary tract epithelium.



Methods: However,
dislodgement of the prothesis, bacterial infection, collaps of the prothesis,
obstruction and strictures due to granulation tissue, urethroperineal fistulas
and stone formation have considerably reduced hopes of success.



Results: In our
investigation the use of tutoplast in construction of a tubular structure at
least 3.5 cm length which could replace the urethral tissue. The tutoplast tube
opposed to the bladder and after, embedding it in the abdominal wall, the
outher mouth of the tube opened to the skin surface.



Conclusion: At the end of this investigation we found that
the inner surface of the tutoplast epitheliased and narrowing or stricture did
not develop. The role of the tutoplast in urethroplasty is excellent.

References

  • Sewell WF, Koth DR, Pate JW. The present status of our experiments with freeze - dried grafts. Noval Med Res Ins No. 1955;13: 291-298.
  • Stolf NA, Curi N, Aun F, Pigossi N, Zerbini EJ. Homologous dura mater used to close thoracic wall and diaphragmatic defects. International surgery. 1976;61(11-12):604-606.
  • Malinin T, Claflin AJ, Brown M, Arango A. Experience with bone and dura mater allografts at the University of Miami Tissue Bank. Acta Medica Polona. 1978;19(1-2):215-228.
  • Kelami A. Duroplasty of the urinary bladder results after two to six years. J Eur Urol. 1975;1:178-181.
  • Gilbaugh JH, Utz DJ, Wakim KG. Partial replacement of the canine urethra with a silicone prothesis. Invest Urol. 1969;7(1):41-46.
  • Hakky SI. The use of fine double siliconised dacron in urethral replacement. Br J Urol. 1977;49(2):167-170.
  • Heller E. Surgical repair of urethral strictures with a silicone ruber patch. J Urol. 1965;94(5):576-580.
  • Palleschi JR, Tanagho EA. Urethral tube graft in dogs. Prothesis of dacron lined silicone. Invest Urol. 1978;15(5):408-412.
  • Kelami A, Rolle KJ, Schnell J, et al. Replacement of the total resected urethra with alloplastic materials experimental studies on dogs. J Urol. 1972;107(1):75-80.
  • Kjaer TB, Nilsson T, et al. Total replacement of part of canine ıırethra with lyophilized vein homografts. Invest Urol. 1976;14(2):159-165.

Tubulerize Tutoplast (Sentetik Duramater) Tup Greftleri ile Tavşan Modelinde Üretroplasti Uygulaması

Year 1996, Volume: 1 Issue: 1, 22 - 24, 30.11.1996

Abstract



Amaç: Günümüzde çocuklarda travma
sonrası genital ve perineal yaralanmalar sık görülmektedir.Çoğu zaman üretrayı
ilgilendiren bu yaralanmalar inkontinans ve üriner obstrüksiyon gibi önemli
komplikasyonlarla sonlanmaktadır. Üretra tıkanmalarında dilatasyon, internal ve
eksternal üretrotomi, üretrotomi ve dilatasyonlarla birlikte steroid
enjeksiyonu bazı olgularda sürekli olmayan iyileşmeler sağlayabilmekte, bununla
birlikte çoğu zaman üretroplastiye ihtiyar duyulmaktadır. Biyolojik olmayan çeşitli
yapıdaki maddeler tüp veya yama halinde üretra lezyonlarının giderilmesi için
kullanılmışlardır.



Yöntem: Üretra protezleri ile yapılan
deneysel çalışmalar genellikle protezin yerinden ayrılması, bakteriyel
enfeksiyon, protezin kollapsına ve granülasyon dokusuna bağlı tam tıkanma ve
darlık oluşumu, üretroperineal fistüller ve protez üzerinde taş oluşması, üretra
onarımında bu maddelerin kullanma ümidini azaltmıştır.



Bulgular: Bu amaçla deneysel çalışmamızda
tavşan modelinde üretra devre dışı bırakılarak 3,5cm'lik tübülerize edilmiş
tutoplastın bir ucu mesane ile ağızlaştırılmış ve karın içine gömüldükten sonra
dış ağız deriye açılmıştır.



Sonuç: Bu çalışma sonunda tutoplasttan oluşturulan tübün
içinin epitelize olduğu, divertikül ve darlık oluşmadığı görülerek bu maddenin
fonksiyon gören neoüretra elde etmek için uygun olduğu görülmüştür.

References

  • Sewell WF, Koth DR, Pate JW. The present status of our experiments with freeze - dried grafts. Noval Med Res Ins No. 1955;13: 291-298.
  • Stolf NA, Curi N, Aun F, Pigossi N, Zerbini EJ. Homologous dura mater used to close thoracic wall and diaphragmatic defects. International surgery. 1976;61(11-12):604-606.
  • Malinin T, Claflin AJ, Brown M, Arango A. Experience with bone and dura mater allografts at the University of Miami Tissue Bank. Acta Medica Polona. 1978;19(1-2):215-228.
  • Kelami A. Duroplasty of the urinary bladder results after two to six years. J Eur Urol. 1975;1:178-181.
  • Gilbaugh JH, Utz DJ, Wakim KG. Partial replacement of the canine urethra with a silicone prothesis. Invest Urol. 1969;7(1):41-46.
  • Hakky SI. The use of fine double siliconised dacron in urethral replacement. Br J Urol. 1977;49(2):167-170.
  • Heller E. Surgical repair of urethral strictures with a silicone ruber patch. J Urol. 1965;94(5):576-580.
  • Palleschi JR, Tanagho EA. Urethral tube graft in dogs. Prothesis of dacron lined silicone. Invest Urol. 1978;15(5):408-412.
  • Kelami A, Rolle KJ, Schnell J, et al. Replacement of the total resected urethra with alloplastic materials experimental studies on dogs. J Urol. 1972;107(1):75-80.
  • Kjaer TB, Nilsson T, et al. Total replacement of part of canine ıırethra with lyophilized vein homografts. Invest Urol. 1976;14(2):159-165.
There are 10 citations in total.

Details

Primary Language Turkish
Subjects ​Internal Diseases
Journal Section Research Articles
Authors

Z.hülya Gündoğdu This is me

Birol Vural This is me

Rıfat Vural This is me

Tülay Evrenkaya This is me

Publication Date November 30, 1996
Submission Date January 1, 1996
Acceptance Date October 1, 1996
Published in Issue Year 1996 Volume: 1 Issue: 1

Cite

AMA Gündoğdu Z, Vural B, Vural R, Evrenkaya T. Tubulerize Tutoplast (Sentetik Duramater) Tup Greftleri ile Tavşan Modelinde Üretroplasti Uygulaması. Acta Med Nicomedia. November 1996;1(1):22-24.

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