Sulbactam+Cefoperazone in Treatment of Complicated Urinary Tract Infections

Year 1996, Volume: 1 Issue: 1, 35 - 36, 30.11.1996

Orhan Yalçın Lütfü Tahmaz İdris Bilgiç Mustafa Yılmaz

Abstract

The
clinical efficacy and safety of sulbactam+cefoperazone combination was
evaluated 30 patients suffering from serious urinary tract infection,
complicated with urinary tract obstruction. All of the patients who were
operating lists, with proven urinary tract infection were given a total daily
dose of 2 gr sulbactam combined with 2 gr cefoperazone. Drug administration
continued for jive days intravenously twice daily. A 90 percent bacteriological
eradication of the isolates was achieved and no significant side effects.
Results of the bacteriological studies together with the clinical course of
patients confirmed excellent therapeutic efficacy and safety of this drug.

Keywords

urinary tract infections, sulbactam, cefaperazone

Komplike Üriner Sistem İnfeksiyonlarinin Tedavisinde Sulbaktam+Sefoperazon

Abstract

Sulbaktam
+ Sefoperazon kombinasyonunun etkinliği ve klinik güvenilirliği, üriner sistem
obstrüksiyonu ile komplike üriner sistem infeksiyonu bulunan 30 hastada
denendi. Hastalann tamamına operasyondan bir gün önce 2 gr sulbaktamla kombine
2 gr sefoperazon total günlük doz olarak başandı. Tedaviye daha sonra beş gün
süre ile aynı doz günde iki defada İV yolla verilerek devam edildi. İzole
edilen bakterilerde %90 oranında eradikasyon sağlanırken önemli bir yan etkiye
rastlanmadı. Sonuç olarak bakteriyolojik ve klinik veriler bu kombinasyonun
üriner sistem infeksiyonlarında etkili ve güvenilir olduğunu gösterdi.

Keywords

Üriner sistem infeksiyonu, sulbaktam, sefoperazon

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