Nötropenik Kanser Hastalarından İzole Edilen Bakteriyel Ajanların İmipenem Duyarlılıkları

Year 1997, Volume: 2 Issue: 1, 36 - 37, 30.01.1997

Erdener Balıkçı M. Orhan Ayyıldız Naci Tiftik Dede Şit Ömer Mete Orhan Yazanel

Abstract

Hematoloji kliniğinde
takip edilen nötropenik kanser hastalarından izole edilen çeşitli bakteriyel
ajanların imipeneme duyarlılıkları araştırıldı. İzole edilen toplam 56
bakteriyel etkenin duyarlılık işlemleri agar-disk diffüzyon metoduyla
gerçekleştirildi. Etkenlerin 16’sı E. Coli, 10’u Pseudomonas spp, 12’si
Enterobacter spp, 5’i Proteus spp, 5’i Klebsiella, 8’i Stafilokok olarak tespit
edildi. Bu etkenlerin imipeneme duyarlılıkları sırasıyla 16 E. Coli suşunun
13’ünde (%81,2), 10 Pseudomonas suşunun 8’inde (%80), 12 Enterobacter suşunun
10’unda (%83,3), 5 Proteus suşunun 4’ünde (%80), 5 Klebsiella suşunun 3’ünde
(%60), 8 Stafilokok suşunun 6’sında (%75) olarak bulundu.

Sonuç olarak imipenemin,
nötropenik kanser hastalarındaki bakteriyel ajanlara karşı önemli oranda
duyarlılığı olan bir antibakteriyel olduğu gözlendi. 

Keywords

Nötropeni, İmipenem

Susceptibilities of Bacterial Agents Isolated from Neutropenic Cancer Patients to Imipenem

Abstract

Susceptibilities
of various bacterial agents to imipenem isolated from neutropenic cancer patients
followed in the department of Hematology were investigated. Susceptibility
procedures of totally 56 isolated bacterial agents were carried out by
agar-disc diffusion method. Of the agents ,16 were found as E. Coli, 10 as
Pseudomonos spp, 12 as Enterobacter spp, 5 as Proteus spp, 5 as Klebsiella, and
8 as Staphyloccocus. The susceptibility of these agents to Imıpenem was
identified in 13 of 16 E. Coli strain (81.2%), 8 of 10 Pseudomonas strain (80%),
10 of 12 Enterobacter strain (83.3%), 4 of 5 Proteus strain (80%), 3 of 5
Klebsiella strain (60%) and 6 of 8 Staphyloccocus strain (75%).

Consequently, it
was observed that Imipenem is an antibacterial agent that has significant
efficacy against bacterial agents in neutropenic cancer patients. 

Keywords

Neutropenia, Imipenem

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