The Relationship Between Metal Element Content of Drinking Water and Body Compositions of People in Batman

Year 2023, Volume: 6 Issue: 3, 320 - 326, 21.10.2023

İhsan Çetin , Selçuk Akın , M Tahir Nalbantçılar , Nazlı Koç , Kezban Tosun

https://doi.org/10.53446/actamednicomedia.1243239

Abstract

Objective: Previous studies showed that the levels of micro elements may have a contribution to weight loss. Nevertheless, it is not possible to find many comprehensive studies analysing the potential relation between micro elements found in water used for drinking purposes and body composition. The present study aims to assess the relation between micro element levels of drinking water and body composition in normal, fat and obese subjects.
Methods: The study consisted of 345 female participants, who were divided into 3 groups of 115, according to body mass index (BMI) for leanness, overweight, and obesity; and who applied to Diet Polyclinic of State Hospital. Water samples were analysed with mass spectrometry; and body composition measurements were conducted via bioelectrical impedance analysis.
Results: The obesity percentage in females demonstrated statistically positive correlations with cobalt (Co) and selenium (Se) in water for drinking. Also, it was found that the BMI values of females significantly positively correlated with chromium (Cr).
Conclusion: It may be suggested that women who consume drinking water containing high levels of Co, Se and Cr might be at a greater risk of developing obesity. On the other hand, the lack of knowledge about influence of levels of micro elements in drinking water on blood parameters associated with obesity or tissue remains unclear and deserves more investigation.

Keywords

Obesity, body mass index, cobalt, selenium, chromium

İçme Suyu Metal Element İçeriği ile Batman'da Yaşayan Bireylerin Vücut Kompozisyonları Arasındaki İlişki

Abstract

Amaç: Önceki çalışmalar mikro element düzeylerinin kilo kaybına katkı sağlayabileceğini göstermiştir. Ancak, içme suyu mikro element düzeyleri ile vücut kompozisyonları arasındaki
potansiyel ilişkiyi analiz eden kapsamlı bir çalışma bulunmamaktadır. Bu çalışmada, içme suyunda bulunan mikro element düzeyleri ile normal, kilolu ve obez kişilere ait vücut kompozisyonları arasındaki ilişkinin incelenmesi amaçlanmıştır.
Yöntem: Bu çalışmaya, Devlet Hastanesi Diyet Polikliniğine başvuran ve vücut kütle indeksi (VKİ) referans değerlerine göre normal, kilolu ve obez olarak üç gruba ayrılan, 55-70 yaş aralığında toplam 345 kadın dâhil edilmiştir. Su örnekleri kütle spektrometresi ile analiz edildi ve vücut kompozisyonu ölçümleri biyoelektrik impedans analizi ile yapılmıştır.
Bulgular: Kadınlara ait obezite yüzdesi, içme suyu kobalt (Co) ve selenyum (Se) düzeyleri
ile pozitif korelasyon gösterdi. Ayrıca, kadınlara ait VKİ değerlerinin içme suyu krom (Cr)
düzeyleri ile pozitif korele olduğu bulundu.
Sonuç: Co, Se ve Cr yüksek düzeyde içeren içme suyu tüketen kadınların obezitenin gelişmesi açısından daha büyük bir risk altında olabileceği öne sürülebilir. Diğer taraftan, içme suyu mikro element seviyelerinin obezite ile ilişkili kan parametrelerine etkisi belirsizdir ve daha fazla araştırmayı hak etmektedir.

Keywords

Obezite, beden kitle indeksi, kobalt, selenyum, krom, Obezite, beden kitle indeksi, kobalt, selenyum, krom, Obesity, body mass index, cobalt, selenium, chromium

References

• Grundy SM. Obesity, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab. 2004;89(6):2595-2600. doi:10.1210/jc.2004-0372
• Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197-1209. doi:10.1016/S0140-6736(05)67483-1
• Yerlikaya H, Toker A. Obesity and trace elements. Dialog Endocrinol 2012;9(2): 64-70
• Gillum RF. Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men: the Third National Health and Nutrition Examination Survey. Int J Obes Relat Metab Disord. 2001;25(5):639-645. doi:10.1038/sj.ijo.0801561
• Zimmermann MB, Zeder C, Muthayya S, et al. Adiposity in women and children from transition countries predicts decreased iron absorption, iron deficiency and a reduced response to iron fortification. Int J Obes (Lond). 2008;32(7):1098-1104. doi:10.1038/ijo.2008.43
• Lecube A, Carrera A, Losada E, Hernández C, Simó R, Mesa J. Iron deficiency in obese postmenopausal women. Obesity (Silver Spring). 2006;14(10):1724-1730. doi:10.1038/oby.2006.198
• Manios Y, Moschonis G, Chrousos GP, et al. The double burden of obesity and iron deficiency on children and adolescents in Greece: the Healthy Growth Study. J Hum Nutr Diet. 2013;26(5):470-478. doi:10.1111/jhn.12025
• Cheng HL, Bryant C, Cook R, O'Connor H, Rooney K, Steinbeck K. The relationship between obesity and hypoferraemia in adults: a systematic review. Obes Rev. 2012;13(2):150-161. doi:10.1111/j.1467-789X.2011.00938.x
• Tuormaa TE. Chromium, Selenium, Copper and other Trace Minerals in Health and Reproduction. J Orthomol Med. 2000;15(3):145-57
• Olusi S, Al-Awadhi A, Abiaka C, Abraham M, George S. Serum copper levels and not zinc are positively associated with serum leptin concentrations in the healthy adult population. Biol Trace Elem Res. 2003;91(2):137-144. doi:10.1385/BTER:91:2:137
• Novakova S, Nikolchev G, Mautner G, Angelieva R, Dinoeva S. Prouchvane vliianieto na niakoi mikroelementi, sudurzhashti se v piteĭnite vodi, vurkhu razvitieto na aterosklerozata [Effect of several microelements contained in drinking water on the development of atherosclerosis]. Probl Khig. 1983;8:121-131
• Bagriacik N, Onat H, Ilhan B, et al. Obesity Profile in Turkey. Int J Endocrinol Metab. 2009;17(1): 5-8. doi:10.1159/000497665
• Błoniarz J, Zareba S. Selected microelements [Cr, Zn, Cu, Mn, Fe, Ni] in slimming preparations. Rocz Panstw Zakl Hig. 2007;58(1): 165-70
• World Health Organization. Calcium and Magnesium in Drinking-water: Public health significance. https://www.who.int/publications/i/item/9789241563550. Published: Mar. 2009. Accessed: Mar 8, 2016
• World Health Organization. Guidelines for Drinking-water Quality. 4th Edition. https://www.who.int/publications/i/item/9789241549950. Published: Jun. 2011. Accessed: Mar 8, 2016
• Neovius M, Hemmingsson E, Freyschuss B, Uddén J. Bioelectrical impedance underestimates total and truncal fatness in abdominally obese women. Obesity (Silver Spring). 2006;14(10):1731-1738. doi:10.1038/oby.2006.199
• Lee SY, Gallagher D. Assessment methods in human body composition. Curr Opin Clin Nutr Metab Care. 2008;11(5):566-572. doi:10.1097/MCO.0b013e32830b5f23
• APHA. Standard methods for the examination of water and wastewater. American Public Health Association Washington, DC, USA. 1992. ACME. Methods and specifications for analytical package, Group 2C & 2D-Water Analysis by ICP-MS [www.acmelab.com], 2005
• Nicolai A, Li M, Kim DH, et al. Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension. 2009;53(3):508-515. doi:10.1161/HYPERTENSIONAHA.108.124701
• Kawakami T, Hanao N, Nishiyama K, et al. Differential effects of cobalt and mercury on lipid metabolism in the white adipose tissue of high-fat diet-induced obesity mice. Toxicol Appl Pharmacol. 2012;258(1):32-42. doi:10.1016/j.taap.2011.10.004
• Laclaustra M, Navas-Acien A, Stranges S, Ordovas JM, Guallar E. Serum selenium concentrations and hypertension in the US Population. Circ Cardiovasc Qual Outcomes. 2009;2(4):369-376. doi:10.1161/CIRCOUTCOMES.108.831552
• Papp LV, Lu J, Holmgren A, Khanna KK. From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal. 2007;9(7):775-806. doi:10.1089/ars.2007.1528
• Stranges S, Sieri S, Vinceti M, et al. A prospective study of dietary selenium intake and risk of type 2 diabetes. BMC Public Health. 2010; 10:564. doi:10.1186/1471-2458-10-564
• Steinbrenner H, Speckmann B, Pinto A, Sies H. High selenium intake and increased diabetes risk: experimental evidence for interplay between selenium and carbohydrate metabolism. J Clin Biochem Nutr. 2011;48(1):40-45. doi:10.3164/jcbn.11-002FR
• Kawakami T, Sugimoto H, Furuichi R, et al. Cadmium reduces adipocyte size and expression levels of adiponectin and Peg1/Mest in adipose tissue. Toxicology. 2010;267(1-3):20-26. doi:10.1016/j.tox.2009.07.022
• Mertz W. Chromium occurrence and function in biological systems. Physiol Rev. 1969;49(2):163-239. doi:10.1152/physrev.1969.49.2.163
• Hasten DL, Rome EP, Franks BD, Hegsted M. Effects of chromium picolinate on beginning weight training students. Int J Sport Nutr. 1992;2(4):343-350. doi:10.1123/ijsn.2.4.343
• Jain SK, Kahlon G, Morehead L, et al. Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study. Mol Nutr Food Res. 2012;56(8):1333-1341. doi:10.1002/mnfr.201100719
• TS-266 (2005) Turkish regulation concerning water intended for human consumption. Institute of Turkish Standard, Ankara, Turkey.
• WHO (2022) Guidelines for drinking-water-quality: Fourth edition incorporating the first and second addenda, World Health Organization, Geneva