Abstract
Amaç: Bağışıklık sistemi, sedef hastalığı olarak bilinen iltihaplı, kalıcı cilt rahatsızlığının kaynağıdır. Sedef hastalığının patolojisinde son zamanlarda kaydedilen önemli gelişmelere rağmen, TNF-Alfa polimorfizmlerini sedef hastalığıyla ilişkilendiren hiçbir bibliyometrik araştırma yürütülmemiştir. Bu çalışmanın amacı, bibliyometrik kullanarak TNF-Alfa Polimorfizmleri ve Sedef Hastalığı'nın odak noktasını ve araştırma genel bakışını değerlendirerek alanın gelişim eğilimini ve sınırlarını daha iyi anlamaktır.
Yöntemler: Web of Science veritabanı 26 Mart 2024'te, başlıkta "resilienc*" terimleri ve konu başlığında "tumor necrosis factor* or TNF or tumo$r necrosis factor*" ve "polymorphism* or variant* or vary* or SNP*" ve "psoriasis OR psoriatic*" terimleriyle arandı. Toplamda 400 belge çıkarıldı. Web-r.org tarafından oluşturulan görselleştirmeler bibliyometrik analiziyle geliştirilen web tabanlı R analizi ile yapıldı.
Bulgular: 2012'den bu yana, sedef hastalığı ve TNF-Alfa polimorfizmleri arasındaki ilişki üzerine yapılan araştırmalar önemli ölçüde arttı. En fazla ilgi gören araştırma Dermatology ve British Journal'da yayınlandı ve Nair RP en fazla atıfı aldı. En üretken ülkeler Çin, Amerika Birleşik Devletleri ve İtalya oldu. "Association", "Romatoid Arthritis" ve "Susceptibility" KeyWordPlus analizinde en sık görülen ifadelerdir.
Sonuç: Gelecekteki araştırmacılar bu çalışmanın sonuçlarını çalışmalarında faydalı bulabilir ve TNF-alfa polimorfizmleri ve sedef hastalığını araştırmak için yeni yollar sunabilir.
Ethical Statement
Bibliyometrik analiz için etik kurul onayı gerekli değildir.
References
- 1. Wang L, Zhou H. A Meta-Analysis of the Relationship between Tumor Necrosis Factor-α Polymorphisms and Psoriasis. Dermatology. 2021;237(1):39-45. doi:10.1159/000502255
- 2. Chokshi A, Demory Beckler M, Laloo A, Kesselman MM. Paradoxical Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor-Induced Psoriasis: A Systematic Review of Pathogenesis, Clinical Presentation, and Treatment. Cureus. 2023;15(8):e42791. doi:10.7759/cureus.42791.
- 3. Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. International journal of molecular sciences, 2019;20(6):1475.
- 4. Baliwag J, Barnes DH, Johnston A. Cytokines in psoriasis. Cytokine. 2015;73(2):342-350. doi:10.1016/j.cyto.2014.12.014
- 5. Jiménez CM, Ramírez CP, Martín AS, et al. Influence of genetic polymorphisms on response to biologics in moderate-to-severe psoriasis. J Pers Med. 2021;11(4). doi:10.3390/jpm11040293
- 6. Aria M, Cuccurullo C. bibliometrix: An R-tool for comprehensive science mapping analysis. J Informetr. 2017;11(4):959-975. doi:10.1016/j.joi.2017.08.007
- 7. Donthu N, Kumar S, Mukherjee D, Pandey N, Lim WM. How to conduct a bibliometric analysis: An overview and guidelines. J Bus Res. 2021;133:285-296. doi:10.1016/j.jbusres.2021.04.070
- 8. Nair RP, Duffin KC, Helms C, et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways. Nature Genetics. 2009;41(2):199-204. doi:10.1038/ng.311
- 9. Stuart PE, Nair RP, Tsoi LC, et al. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Am J Hum Genet. 2015;97(6):816-836. doi:10.1016/j.ajhg.2015.10.019
- 10. Wang Y, Li J, Guo C, Yang G, Lin H, Zhang Y. Bibliometric analysis and description of research trends in the treatment of psoriasis with biologic agents in the past two decades (2004–2023). J Dermatol Treat. 2024;35(1). doi:10.1080/09546634.2024.2346282
Abstract
Purpose: The immune system is the source of the inflammatory, persistent skin condition known as psoriasis. Despite recent major advancements in the pathology of psoriasis, no bibliometric investigation associating TNF-Alpha polymorphisms to psoriasis has been conducted. The objective of this study was to better understand the development trend and boundaries of the area by using bibliometrics to assess the focal point and research overview of TNF-Alpha Polymorphisms and Psoriasis.
Methods: The Web of Science database was searched on March 26, 2024, with the terms “resilienc*” in the title and “tumo$r necrosis factor* or TNF or tumo$r necrosis factor*” and “polymorphism* or variant* or variation* or SNP*” and “psoriasis OR psoriatic*” in the topic. There were 400 documents extracted in all. Visualizations created by web-r.org were made using web-based R analytics developed with bibliometric analysis.
Results: Since 2012, research on the relationship between psoriasis and TNF-Alpha polymorphisms has increased significantly. The research that received the most attention was published in Dermatology and the British Journal, with Nair RP receiving the most citations. China, the United States, and Italy were the most productive nations. "Association," "Rheumatoid Arthritis," and "Susceptibility" appeared most frequently in the KeyWordPlus analysis.
Conclusion: Future researchers may find the results of this study useful in their work, and it may present new avenues for investigating TNF-alpha polymorphisms and psoriasis.
References
- 1. Wang L, Zhou H. A Meta-Analysis of the Relationship between Tumor Necrosis Factor-α Polymorphisms and Psoriasis. Dermatology. 2021;237(1):39-45. doi:10.1159/000502255
- 2. Chokshi A, Demory Beckler M, Laloo A, Kesselman MM. Paradoxical Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor-Induced Psoriasis: A Systematic Review of Pathogenesis, Clinical Presentation, and Treatment. Cureus. 2023;15(8):e42791. doi:10.7759/cureus.42791.
- 3. Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. International journal of molecular sciences, 2019;20(6):1475.
- 4. Baliwag J, Barnes DH, Johnston A. Cytokines in psoriasis. Cytokine. 2015;73(2):342-350. doi:10.1016/j.cyto.2014.12.014
- 5. Jiménez CM, Ramírez CP, Martín AS, et al. Influence of genetic polymorphisms on response to biologics in moderate-to-severe psoriasis. J Pers Med. 2021;11(4). doi:10.3390/jpm11040293
- 6. Aria M, Cuccurullo C. bibliometrix: An R-tool for comprehensive science mapping analysis. J Informetr. 2017;11(4):959-975. doi:10.1016/j.joi.2017.08.007
- 7. Donthu N, Kumar S, Mukherjee D, Pandey N, Lim WM. How to conduct a bibliometric analysis: An overview and guidelines. J Bus Res. 2021;133:285-296. doi:10.1016/j.jbusres.2021.04.070
- 8. Nair RP, Duffin KC, Helms C, et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways. Nature Genetics. 2009;41(2):199-204. doi:10.1038/ng.311
- 9. Stuart PE, Nair RP, Tsoi LC, et al. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Am J Hum Genet. 2015;97(6):816-836. doi:10.1016/j.ajhg.2015.10.019
- 10. Wang Y, Li J, Guo C, Yang G, Lin H, Zhang Y. Bibliometric analysis and description of research trends in the treatment of psoriasis with biologic agents in the past two decades (2004–2023). J Dermatol Treat. 2024;35(1). doi:10.1080/09546634.2024.2346282
Details
| Primary Language | English |
|---|---|
| Subjects | Dermatology, Public Health (Other) |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | February 28, 2025 |
| Submission Date | September 24, 2024 |
| Acceptance Date | February 27, 2025 |
| Published in Issue | Year 2025 Volume: 8 Issue: 1 |
The articles in the Journal of "Acta Medica Nicomedia" are open access articles licensed under a Creative Commons Attribution-ShareAlike 4.0 International License at the web address https://dergipark.org.tr/tr/pub/actamednicomedia