Case Report
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A Rare Cause of Abdominal Pain: Gastric Glomus Tumor

Year 2025, Volume: 8 Issue: 1, 84 - 87, 28.02.2025
https://doi.org/10.53446/actamednicomedia.1600678

Abstract

Objective: Glomus tumors are typically benign soft tissue tumors located in the extremities; however, they can also rarely occur in other parts of the body, such as the gastrointestinal (GI), urogenital, and respiratory systems. In the GI system, the majority of glomus tumors are found in the gastric antrum. These tumors are generally small in size (<4 cm) but may occasionally reach larger dimensions. This report focuses on a case of a gastric glomus tumor in a patient presenting with abdominal pain.

Method: This report presents a case of a 48-year-old female patient who visited our clinic with complaints of intermittent abdominal pain, nausea, and vomiting over a two-month period. Upper GI endoscopy revealed a submucosal lesion located on the lesser curvature of the stomach.

Findings: The patient underwent partial gastrectomy encompassing the lesion. The diagnosis of a glomus tumor was confirmed through immunohistochemical examination.

Conclusion: Glomus tumors are generally benign and do not require radical surgery. The most critical aspect is ensuring a definitive histological diagnosis and distinguishing these tumors from other more common gastric lesions, particularly malignant tumors.

References

  • Ortenzi M, Ghiselli R, Cardinali L, Guerrieri M. Surgical treatment of gastric stromal tumors: laparoscopic versus open approach. Ann Ital Chir. 2017;88:S0003469X17026112.
  • Guvendir I, Zemheri IE, Altundal K, Ozdil K, Kahraman R, Tosun I. Ossified uncertain malignant potential gastric glomus tumor with tumor thrombus. Indian J Pathol Microbiol. 2021;64(2):369-372. doi:10.4103/IJPM.IJPM_374_20
  • Tsagkataki ES, Flamourakis ME, Gkionis IG, et al. Gastric glomus tumor: a case report and review of the literature. J Med Case Rep. 2021;15(1):415. Published 2021 Aug 16. doi:10.1186/s13256-021-03011-0
  • Frosio F, Petruzziello C, Poiasina E, Pisano M, Lucianetti A. Locally Advanced Glomus Tumor of the Stomach With Synchronous Liver Metastases: Case Report and Literature Review. Cureus. 2023;15(12):e51041. Published 2023 Dec 24. doi:10.7759/cureus.51041
  • Xing JJ, Huang WP, Wang F, Chai YR, Gao JB. Computed tomography features and clinicopathological characteristics of gastric glomus tumor. BMC Gastroenterol. 2022;22(1):174. Published 2022 Apr 9. doi:10.1186/s12876-022-02241-w
  • Lee HW, Lee JJ, Yang DH, Lee BH. A clinicopathologic study of glomus tumor of the stomach. J Clin Gastroenterol. 2006;40(8):717-720. doi:10.1097/00004836-200609000-00011
  • Wang X, Hanif S, Wang B, Chai C. Management of gastric glomus tumor: A case report. Medicine (Baltimore). 2019;98(38):e16980. doi:10.1097/MD.0000000000016980
  • Zhang Y, Zhou P, Xu M, et al. Endoscopic diagnosis and treatment of gastric glomus tumors. Gastrointest Endosc. 2011;73(2):371-375. doi:10.1016/j.gie.2010.10.023
  • Deng M, Luo R, Huang J, et al. Clinicopathologic features of gastric glomus tumor: A report of 15 cases and literature review. Pathol Oncol Res. 2023;28:1610824. Published 2023 Jan 9. doi:10.3389/pore.2022.1610824
  • Kato S, Kikuchi K, Chinen K, Murakami T, Kunishima F. Diagnostic utility of endoscopic ultrasound-guided fine-needle aspiration biopsy for glomus tumor of the stomach. World J Gastroenterol. 2015;21(22):7052-7058. doi:10.3748/wjg.v21.i22.7052
  • Wang ZB, Yuan J, Shi HY. Features of gastric glomus tumor: a clinicopathologic, immunohistochemical and molecular retrospective study. Int J Clin Exp Pathol. 2014 Mar 15;7(4):1438-48. PMID: 24817939.

Nadir bir karın ağrısı nedeni: Midenin glomus tümörü

Year 2025, Volume: 8 Issue: 1, 84 - 87, 28.02.2025
https://doi.org/10.53446/actamednicomedia.1600678

Abstract

Amaç:Glomus tümörleri genellikle ekstremitelerde yer alan, iyi huylu yumuşak doku tümörleridir; ancak gastrointestinal sistem (GİS), ürogenital ve solunum sistemi gibi vücudun diğer bölgelerinde de nadiren görülebilir. GİS’teki glomus tümörlerinin çoğunluğu mide antrumunda bulunur. Bu tümörler genellikle küçük çaplıdır (<4 cm), ancak bazen daha büyük boyutlara ulaşabilirler. Bu yazıda mide karın ağrısı şikayeti ile gelen ve tetkikler sonucunda mide glomus tümörü tanısı alan bir olgu üzerinde durulacaktır.
Yöntem:Bu yazıda, iki aydır aralıklı olarak karın ağrısı bulantı, kusma şikayetleri olan ve bu şikayetlerle kliniğimize başvuran 48 yaşındaki kadın hastada saptanan mide glomus tümörü olgusu sunulmuştur. Üst GİS endoskopisinde mide küçük kurvaturda, submukozal bir lezyon tespit edilmiştir.
Bulgular:Hastaya, lezyonu kapsayan bir parsiyel gastrektomi ameliyatı yapılmıştır. Glomus tümörünün teşhisi, immünohistokimyasal inceleme ile doğrulanmıştır
Sonuç:Glomus tümörleri genellikle benign olup, radikal cerrahi gerektirmez; bu nedenle en önemli husus, histolojik tanının kesin olarak konulması ve midenin daha sık görülen diğer lezyonlarından, özellikle de malign tümörlerden ayırt edilmesidir.

References

  • Ortenzi M, Ghiselli R, Cardinali L, Guerrieri M. Surgical treatment of gastric stromal tumors: laparoscopic versus open approach. Ann Ital Chir. 2017;88:S0003469X17026112.
  • Guvendir I, Zemheri IE, Altundal K, Ozdil K, Kahraman R, Tosun I. Ossified uncertain malignant potential gastric glomus tumor with tumor thrombus. Indian J Pathol Microbiol. 2021;64(2):369-372. doi:10.4103/IJPM.IJPM_374_20
  • Tsagkataki ES, Flamourakis ME, Gkionis IG, et al. Gastric glomus tumor: a case report and review of the literature. J Med Case Rep. 2021;15(1):415. Published 2021 Aug 16. doi:10.1186/s13256-021-03011-0
  • Frosio F, Petruzziello C, Poiasina E, Pisano M, Lucianetti A. Locally Advanced Glomus Tumor of the Stomach With Synchronous Liver Metastases: Case Report and Literature Review. Cureus. 2023;15(12):e51041. Published 2023 Dec 24. doi:10.7759/cureus.51041
  • Xing JJ, Huang WP, Wang F, Chai YR, Gao JB. Computed tomography features and clinicopathological characteristics of gastric glomus tumor. BMC Gastroenterol. 2022;22(1):174. Published 2022 Apr 9. doi:10.1186/s12876-022-02241-w
  • Lee HW, Lee JJ, Yang DH, Lee BH. A clinicopathologic study of glomus tumor of the stomach. J Clin Gastroenterol. 2006;40(8):717-720. doi:10.1097/00004836-200609000-00011
  • Wang X, Hanif S, Wang B, Chai C. Management of gastric glomus tumor: A case report. Medicine (Baltimore). 2019;98(38):e16980. doi:10.1097/MD.0000000000016980
  • Zhang Y, Zhou P, Xu M, et al. Endoscopic diagnosis and treatment of gastric glomus tumors. Gastrointest Endosc. 2011;73(2):371-375. doi:10.1016/j.gie.2010.10.023
  • Deng M, Luo R, Huang J, et al. Clinicopathologic features of gastric glomus tumor: A report of 15 cases and literature review. Pathol Oncol Res. 2023;28:1610824. Published 2023 Jan 9. doi:10.3389/pore.2022.1610824
  • Kato S, Kikuchi K, Chinen K, Murakami T, Kunishima F. Diagnostic utility of endoscopic ultrasound-guided fine-needle aspiration biopsy for glomus tumor of the stomach. World J Gastroenterol. 2015;21(22):7052-7058. doi:10.3748/wjg.v21.i22.7052
  • Wang ZB, Yuan J, Shi HY. Features of gastric glomus tumor: a clinicopathologic, immunohistochemical and molecular retrospective study. Int J Clin Exp Pathol. 2014 Mar 15;7(4):1438-48. PMID: 24817939.
There are 11 citations in total.

Details

Primary Language Turkish
Subjects Surgery (Other)
Journal Section Olgu Sunumu
Authors

Mehmet Fatih Özsaray 0000-0001-9290-4899

Turgay Şimşek 0000-0002-5733-6301

Zafer Cantürk 0000-0002-0042-9742

Publication Date February 28, 2025
Submission Date December 12, 2024
Acceptance Date February 5, 2025
Published in Issue Year 2025 Volume: 8 Issue: 1

Cite

AMA Özsaray MF, Şimşek T, Cantürk Z. Nadir bir karın ağrısı nedeni: Midenin glomus tümörü. Acta Med Nicomedia. February 2025;8(1):84-87. doi:10.53446/actamednicomedia.1600678

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