Diş Materyallerde Kadmiyum Toksisitesi: Ağız Kanserinde Rol Oynayabilir mi? Sistematik Bir Derleme

Öz

Kanserojen/toksik eser elementlerden biri olan kadmiyum, tütüne bağlı oral kanser (OK) araştırmalarında önemli bir alt başlıktır. Kadmiyumun dental materyallerdeki toksisitesi ve OK oluşumundaki rolü PubMed'deki makaleler kullanılarak araştırıldı. Böylece, bu veri tabanından toplam 13 çalışma incelemeye dahil edilmiştir. Dental materyallerdeki kadmiyumun genel olarak toksik etkilere neden olmayacak düzeyde olduğu ortaya konmuştur. Ayrıca tütün ürünleri, gıdalar, hava kirliliği ve içme suyu gibi kadmiyumun önemli kaynaklarının bulunduğu günümüzde kadmiyum kaynaklı OK oluşumunda dental materyallerin etyolojik faktörler arasında olamayacağı söylenebilir.

Anahtar Kelimeler

• Kadmiyum
• Diş Materyal
• Ağız Kanseri
• Kadmiyum Toksisitesi

Cadmium Toxicity in Dental Materials: Could it Play a Role in Oral Cancer? A Systematic Review

Abstract

Cadmium, one of the carcinogenic/toxic trace elements, is an important sub-title in tobacco-related oral cancer (OC) research. The toxicity of cadmium in dental materials and its role in OC formation were investigated using articles in PubMed. Thus, a total of 13 studies from these databases were included in the review. It has been revealed that cadmium in dental materials is generally at a level that cannot cause toxic effects. In addition, it can be said that dental materials cannot be among the etiological factors in the formation of cadmium-induced OC today, where there are major sources for cadmium such as tobacco products, foods, air pollution and drinking water.

Keywords

• Cadmium
• Dental materials
• Oral cancer
• Cadmium toxicity

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