Comparative Evaluation of DMF Scores in Patients Using Bisphosphonates: A Retrospective Study

Year 2025, Volume: 4 Issue: 3, 198 - 203, 30.12.2025

Nilay Bayraktar , Menekşe Ersoysal , Aysu Zeynep Yüce , Emir Mehmet Ersöz , Ali Taş , Osman Harorlı

https://doi.org/10.62268/add.1818180

Abstract

Objectives
This study aimed to evaluate the association between bisphosphonate use and the prevalence of dental caries in comparison with systemically healthy controls.
Material and Methods
This retrospective study included 100 patients: 50 were on bisphosphonate medication and 50 were healthy controls who were matched for age and gender. Between 2013 and 2023, each participant was recorded in the database of Akdeniz University's Faculty of Dentistry. Dental health markers, such as the number of undamaged teeth, restorations, and the prevalence of caries, were evaluated using panoramic radiography. The analysis did not include third molars. Following established standards, two skilled dentists independently assessed the radiographs. Patients between the ages of 18 and 70 were included in the inclusion criteria, however those with major radiographic artifacts, crowns, implants, or tooth loss were excluded. The end measures included the DMF index, the number of caries-affected teeth, the number of teeth that were treated, and the number of teeth that were fully intact. To use the independent samples t-test for statistical analysis, these parameters were compared between the bisphosphonate and control groups (P < 0.05).
Results
There was no statistically significant difference between the groups (p = 0.26), with the mean DMF index for healthy people being 8.42 and for bisphosphonate users being 9.32. The number of restored teeth (3.0 vs. 2.4, respectively; p = 0.08), carious teeth (2.08 vs. 2.34, respectively; p = 0.52), and sound teeth (20.12 vs. 20.32, respectively; p = 0.59) did not differ significantly either.
Conclusion
The DMF index, the number of sound teeth, restored teeth, and carious teeth did not differ statistically significantly between bisphosphonate users and healthy people. The DMF index did not significantly rise among bisphosphonate users. It is advised that bigger sample sizes be used in future research to validate these results.

Keywords

Bisphosphonates , Dental caries , DMF index , Panoramic x-ray

Ethical Statement

The study was approved by the Akdeniz University Ethics Committee (2025/192).

Supporting Institution

The author declared that this study has received no financial support.

Bifosfonat Kullanan hastalarda DMF Skorlarının Karşılaştırmalı Değerlendirmesi: Bir Retrospektif Çalışma

Abstract

Amaç
Bu çalışmanın amacı, sistemik olarak sağlıklı bireylerle karşılaştırıldığında hastalarda çürük görülme sıklığı ile bifosfonat kullanımı arasındaki ilişkiyi araştırmaktır.
Gereç ve Yöntemler
Bu retrospektif çalışmada 100 hasta yer aldı: 50'si bisfosfonat tedavisi gören hastalar, 50'si ise yaş ve cinsiyet açısından eşleştirilmiş sağlıklı kontrol grubu hastalarıdır. 2013 ile 2023 yılları arasında, her katılımcı Akdeniz Üniversitesi Diş Hekimliği Fakültesi'ne bir giriş yapmıştır. Sağlam diş sayısı, restorasyonlar ve çürük prevalansı gibi diş sağlığı bulguları panoramik radyografiler kullanılarak değerlendirildi. Analiz üçüncü molarları kapsamadı. Yerleşik standartlara göre, iki uzman diş hekimi radyografileri bağımsız değerlendirdi. Çalışmaya 18–70 yaş aralığındaki hastalar dahil edildi, ancak radyografik artefaktları bulunanlar, kronu, implantı olanlar ya da diş kaybı bulunanlar ise dışlandı. Son ölçümler arasında DMF indeksi, çürükten etkilenen diş sayısı, tedavi edilen diş sayısı ve tamamen sağlam diş sayısı yer aldı. İstatistiksel analiz için bağımsız örnekler t-testi kullanmak üzere, bu parametreler bisfosfonat ve kontrol grupları arasında karşılaştırıldı (P < 0,05).
Bulgular
Gruplar arasında istatistiksel olarak anlamlı bir fark yoktu (p = 0.26), sağlıklı kişilerde ortalama DMF indeksi 8.42, bifosfonat kullanıcılarında ise 9.32 idi. Restore edilmiş diş sayısı (sırasıyla 3.0 ve 2.4; p = 0.08), çürük diş sayısı (sırasıyla 2.08 ve 2.34; p = 0.52) ve sağlam diş sayısı (sırasıyla 20.12 ve 20.32; p = 0.59) arasında da istatistiksel olarak anlamlı bir fark görülmedi.
Sonuç
DMF indeksi, sağlam diş sayısı, restore edilmiş diş sayısı ve çürük diş sayısı, bifosfonat kullanıcıları ile sağlıklı kişiler arasında istatistiksel olarak anlamlı bir fark göstermemiştir. DMF indeksi, bifosfonat kullanıcıları arasında anlamlı bir artış göstermemiştir. Bu sonuçları doğrulamak için gelecekteki araştırmalarda daha büyük örneklemlerin kullanılması tavsiye edilir.

Keywords

Bisfosfonatlar , Diş çürükleri , DMF indeksi , Panoramik röntgen

Ethical Statement

The study was approved by the Akdeniz University Ethics Committee (2025/192).

Supporting Institution

The author declared that this study has received no financial support.

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