Is there any association between ABO blood types and slow coronary flow?

Year 2019, Volume: 5 Issue: 2, 1492 - 1499, 15.08.2019

Hakan Kaya

https://doi.org/10.30569/adiyamansaglik.552822

Abstract

Aim: Slow coronary
flow (SCF) is defined as a microvascular disorder characterized by slow advance
of the contrast material administered during angiography, despite absence of
epicardial coronary artery occlusion and delayed opacification of distal
vascular structures. Genetically inherited ABO blood types are presumed to play
role in coronary artery disease. In this study, the relationship between SCF
and ABO blood types was investigated.

Methods: The study
was designed as a retrospective study, and included 250 cases that underwent
coronary angiography procedure in our center between 2016 January and 2018
December (one hundred and twenty five cases of SCF and 125 cases of normal
coronary angiogram). ABO blood types were determined using standard
agglutination techniques in both study groups. Blood types were compared
between both subject groups.

Results: The
frequency of blood type A was increased among patients with SCF in comparison
with control subjects (p<0.001). High density lipoprotein cholesterol was
increased in SCF group (p<0.001). Triglyceride, , total cholesterol and low
density lipoprotein cholesterol levels were 
increased in the SCF group when compared to controls (p=0.003,
p<0.001, and p<0.001, respectively).

Keywords

ABO blood types, slow coronary flow, Cardiology

Is there any association between ABO blood types and slow coronary flow?

Abstract

Amaç: Koroner yavaş akım (KYA), epikardiyal
koroner arter tıkanıklığı olmamasına rağmen, anjiyografi sırasında uygulanan kontrast
maddenin yavaş ilerlemesi ve distal vasküler yapıların gecikmeli opaklaşması
ile karakterize bir mikrovasküler bozukluk olarak tanımlanmaktadır Genetik olarak
taşınan ABO kan gruplarının koroner arter hastalığında rol oynadığı
varsayılmaktadır. Bu çalışmada KYA ve ABO kan grupları arasındaki ilişki
araştırıldı.

Gereç
ve yöntemler:  Çalışma retrospektif bir çalışma olarak
tasarlandı ve merkezimizde Ocak 2016 - Aralık 2018 tarihleri ​​arasında koroner
anjiyografi prosedürü uygulanan 250 vaka (125 KYA hastası ve 125 normal koroner
anjiyogram vakası) çalışmaya dahil edildi. Her iki çalışma
grubunda da ABO kan tipleri standart aglütinasyon teknikleri kullanılarak
belirlendi. Her iki grup arasında kan tipleri karşılaştırıldı.

Bulgular: KYA hastalarında A kan grubu sıklığı
kontrol grubuna kıyasla artmıştı (p<0.001). 
Kontol grubunda yüksek dansiteli lipoprotein kolesterol artmıştı (p<0.001).
Kontrol grubuna kıyasla trigliserit, total kolesterol ve düşük dansiteli lipoprotein
kolesterol düzeyleri KYA grubunda artmıştı ( 
p =0.003, p<0.001, p<0.001, sırasıyla).

Sonuç: Bu çalışma, A kan grubunun KYA için artmış
bir risk olabileceğini ortaya koydu.

Keywords

ABO kan grupları, koroner yavaş akım, kardiyoloji

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