Mide kanseri hastalarında tümör lokalizasyonu ve lenf nodu tutulumunun prognoz ve sağkalıma etkisi

Year 2020, Volume: 6 Issue: 2, 248 - 257, 30.08.2020

Cihan Gökler Oktay İrkorucu Enver Reyhan Hilmi Bozkurt Mustafa Görür

https://doi.org/10.30569/adiyamansaglik.717688

Abstract

Amaç: Mide kanseri nedeniyle ameliyat edilen hastalarda tümör yerleşimi ve lenf nodu tutulumunun prognoz ve sağkalım üzerine etkisini değerlendirmeyi amaçladık.
Gereç ve Yöntem: Prognostik faktörleri belirlemek için kliniğimizde ameliyat edilen hastaların klinik ve histopatolojik özelliklerini araştırdık.
Bulgular: Tümör lokalizasyon grupları arasında ve metastatik lenf noduna göre sağkalım farkı gözlenmedi (Log Rank p=0,255 ve 0,188). Evreye ve 60 yaş üstü olma durumuna göre anlamlı sürvi farkı vardı (p=0,001, p=0,003). Üst 1/3 yerleşimli gastrik kanserde diseke edilen metastatik lenf nodu sayısı fazlaydı (p=0,026, 0,036)
Sonuç: Mide kanseri hastalarında tümör lokalizasyonu ve lenf nodu tutulumunun sürviye etkisi saptanmamışken, 60 yaş üzeri olma ve Evre-III kötü prognostik faktörler olarak saptandı.

Keywords

Mide Kanseri, Gastrektomi, Metastatik Lenf Nodu, İleri yaş, Prognoz

Supporting Institution

Herhangi bir kurum desteği yoktur

Thanks

Adana Şehir Hastanesi Genel Cerrahi kliniğine teşekkür ederiz.

Effect of tumor location and lymph node involvement on prognosis and survival in gastric cancer patients

Abstract

Aim: The present study evaluates the effect of tumor localization and lymph node involvement on prognosis and survival in patients undergoing surgery for gastric cancer.
Materials and Methods: The clinical and histopathological characteristics of patients who underwent surgery in our clinic were evaluated to determine the prognostic factors.
Results: No difference was observed in the survival rates of the groups in terms of tumor locations and metastatic lymph nodes (Log Rank p=0.255 and 0.188). A significant difference was found in the survival rates of the groups based on stage and age over 60 years (p=0.001, p=0.003). The number of metastatic lymph nodes dissected was high in gastric cancers located in the upper-third of the stomach (p=0.026, 0.036).
Conclusion: No effect of tumor localization or lymph node involvement was determined on survival in patients with gastric cancer; however, age over 60 years and stage III were found to be poor prognostic factors.

Keywords

Gastric Cancer, Gastrectomy, Metastatic Lymph Nodes, Advanced Age, Prognosis

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