Corrected TLC-Data of 16 Hydrolysis-Derivatives of Commonly Used Benzodiazepines in 10 Systems

Abstract

In addition to the corrected Rf- values of 61 benzodiazepines and metabolites which were recently published in this journal [Adli Tıp Derg. (ATD), 1, 22-29 (1985)] we have investigated the corrected Rf- values of 16 hydrolysis products (aminobenzophenones and benzoylpyridines) in 10 (!) systems. These cleavage products may occur as metabolites in some cases and/or artefacts in biological materials. They are, in addition to this minor important fact, the basis of largely applied screening met hods.

Keywords

• Benzodiazepines
• Metabolites
• Aminobenzophenones

References

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