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TLC-Screening of 1,4-Benzodiazepines

Year 1990, Volume: 6 Issue: 1-2, 1 - 6, 30.04.1990

Harald Schütz Ehrengard Rumpf

https://izlik.org/JA59RB67RZ

Abstract

Thin-Iayer chromatography (TLC) is the preferred method for screening benzodiazepines and their metabolites. The procedure involves hydrolysis to yield aminobenzophenone derivatives, which are then extracted, separated by TLC and photolytically dealkylated. The products are diazotized and coupled with aze-dye (e.g. the Bratton-Marshall reagent). The method has aıready been applied to numerous benzodiazepines (l -S) and its specificity established (6).

Keywords

Benzodiazepines TLC Screening

References

  • Schütz, H. (1982) Bemodiaıepitıes il lIandb.wk, Spııng::!" Verlag. Berlin-Hr:idelberg. York. Tokyo.
  • Schütz, H. (1982) Arıtl. Lab., 28, 47.
  • Schütz, H. (1986) Dünnschicht-chromatographische Suchanalyse jür 1,4-Benzodiaıepine im Ham. Blu.! Magnıinha/t (Miiıcilung der Sen;ıtskommi."ion der für K1iııisch-toxık()L)gischl" Analytik), Verlagsgcsellschar:, Weinhclm.
  • Sehneider,W.-R., Sehütz, IL, Zcller, M. (1986) Adli Tıp Derg., 2,56-60.
  • Schütz, H. (191\9) Benıodiazepines IT. Springer. Berlin-! TeidcJbcrg-New York-Tokyo.
  • Schütz, H., Fitz, II., Suphaehcarabhın, S. (1983) Freseni"s' Z. And!. Chem" 44.

Year 1990, Volume: 6 Issue: 1-2, 1 - 6, 30.04.1990

Harald Schütz Ehrengard Rumpf

https://izlik.org/JA59RB67RZ

Abstract

References

  • Schütz, H. (1982) Bemodiaıepitıes il lIandb.wk, Spııng::!" Verlag. Berlin-Hr:idelberg. York. Tokyo.
  • Schütz, H. (1982) Arıtl. Lab., 28, 47.
  • Schütz, H. (1986) Dünnschicht-chromatographische Suchanalyse jür 1,4-Benzodiaıepine im Ham. Blu.! Magnıinha/t (Miiıcilung der Sen;ıtskommi."ion der für K1iııisch-toxık()L)gischl" Analytik), Verlagsgcsellschar:, Weinhclm.
  • Sehneider,W.-R., Sehütz, IL, Zcller, M. (1986) Adli Tıp Derg., 2,56-60.
  • Schütz, H. (191\9) Benıodiazepines IT. Springer. Berlin-! TeidcJbcrg-New York-Tokyo.
  • Schütz, H., Fitz, II., Suphaehcarabhın, S. (1983) Freseni"s' Z. And!. Chem" 44.
There are 6 citations in total.

Details

Primary Language English
Subjects Forensic Biology
Journal Section Research Article
Authors

Harald Schütz This is me

Ehrengard Rumpf This is me

Submission Date January 1, 1990
Publication Date April 30, 1990
IZ https://izlik.org/JA59RB67RZ
Published in Issue Year 1990 Volume: 6 Issue: 1-2

Cite

Vancouver 1.Harald Schütz, Ehrengard Rumpf. TLC-Screening of 1,4-Benzodiazepines. J For Med [Internet]. 1990 Apr. 1;6(1-2):1-6. Available from: https://izlik.org/JA59RB67RZ
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