Tissue Engineering in Dentistry

Year 2018, Volume: 9 Issue: 1, 1601 - 1608, 01.01.2018

Hümeyra Yazar İnci Rana Karaca

Abstract

Orofacial structures are very characteristic in their development and functions. Various conditions may necessitate either soft or hard tissue reconstruction. Autogenous soft and hard tissue grafts are gold standard for reconstruction but because of donor site morbidity, their use is limited. Tissue engineering is a developing and interdisciplinary field that uses engineering principles to solve biological problems. In recent years, regenerative medicine has established its place as an alternative method for the treatment of hard and soft tisue defects using cell therapy, growth factor application, and scaffolds. In this review, we aimed to give information about developing tissue engineering and the material and methods used

Keywords

Tissue engineering, scaffolds, therapy, gene, growth factors, stem cells

Diş Hekimliğinde Doku Mühendisliği

Abstract

Orofasial yapılar gelişim ve fonksiyon açısından kendine özgüdür. Bu yapılarda çeşitli sebeplerle sert ve yumuşak doku rekonstrüksiyonu gerekli hale gelebilmektedir. Otojen yumuşak ve sert doku greftleri onarımda altın standart olmasına rağmen donör saha morbiditesi kullanımlarını sınırlandırmaktadır. Doku mühendisliği; mühendislik prensiplerini biyolojik problemlerin çözümü amacıyla kullanmak üzere gelişen interdisipliner bir alandır. Son yıllarda, hücre terapileri, büyüme faktörleri uygulamaları ve doku iskelelerini içeren rejeneratif tedavi seçenekleri kemik defektlerinin onarımlarında alternatif bir yöntem olarak yer edinmiştir. Bu derlemede gelişen doku mühendisliği, kullanılan gereç ve yöntemlerle ilgili bilgi verilmesi amaçlanmıştır

Keywords

Doku mühendisliği, doku iskeletleri, terapi, gen, büyüme faktörleri, kök hücreler

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