Novel approaches for Caries Prevention

Year 2012, Volume: 6 Issue: 3, 1284 - 1292, 01.10.2012

Çiğdem Çelik

Abstract

Dental caries is one of the most common preventable childhood diseases; people are susceptible to this ailment throughout their lifetime. The definition of dental caries is the localized destruction of susceptible dental hard tissues by acidic by-products from bacterial fermentation of dietary carbohydrates. The most important effect on caries prevention, enhancement of remineralization, only can occur in the presence of calcium and phosphate ions. This review focuses on the recent development of various novel technologies for the prevention and treatment of dental caries. Recent advances in anti-plaque agents, including chemoprophylactic agents, antimicrobial peptides, probiotics/replacement therapy and sugar substitutes, and remineralization agents including fluorides, casein phosphopeptides and bioactive glasses are analyzed

Keywords

Dental caries, prevention, antimicrobials, probiotics, caries vaccine, fluorides, sugar substitudes, casein phosphopeptides, bioactive glass

Diş Çürüklerinin Önlenmesinde Güncel Yaklaşımlar

Abstract

Diş çürüğü, bireyleri hayatları boyunca etkileyen, sık görülen ve önlenebilir bir çocukluk çağı hastalığıdır. Diş çürüğü bakterilerin fermente ettiği karbonhidratların asidik yan ürünlerinin diş sert dokularında yarattığı lokalize yıkım olarak tanımlanabilir. Diş çürüğünün önlenmesinde en önemli etki kalsiyum ve fosfat iyonlarının varlığında gerçekleşen remineralizasyonla sağlanmaktadır. Bu derlemede diş çürüğünün önlenmesi ve tedavisinde yakın zamanda olan gelişmeler yer almaktadır. Bu kapsamda, kemoprofilaktik ajanlar, antimikrobiyal peptitler, probiyotikler ve yer değiştirme tedavisi, şeker değişkenleri, florür, kazein fosfopeptit ve biyoaktif cam içeren remineralize edici ajanlardaki gelişmeler değerlendirilmektedir

Keywords

Diş çürüğü, koruyucu tedaviler, antimikrobiyaller, probiyotikler, çürük aşısı, florürler, şeker değişkenleri, kazein fosfopeptitler, biyoaktif cam

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