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Year 2025, Volume: 15 Issue: 1, 98 - 127, 01.07.2025
https://doi.org/10.37094/adyujsci.1578202

Abstract

References

  • Babalola, O.O, Adebisi, A.F, Odeyemi, K.A., Numerical Solution for Linear Integro-Differential Equations using Shifted Legendre Basis Functions, Jurnal Diferensial, Indonesia, 7, 55–72, 2025.
  • Olaosebikan, M.L., Kolawole, M.K., Bashiru, K.A., Transmission Dynamics of Tuberculosis Model with Control Strategies, Jambura Journal of Biomathematics, 4(2), 110–118, 2023.
  • Dere Z.O, Oladapo, A.O., Mathematical (Seirb) Model Analysis for Evaluating Cholera Control Strategies in Remote Dry Season Region, Jurnal Diferensial, 6, 142–169, 2024.
  • Harpring, R., Maghsoudi, A., Fikar, C., Piotrowicz, W.D., An Analysis of compounding factors of Epidemics in Complex Emergencies: a System Dynamics Approach, Journal of Humanitarian Logistics and Supply Chain Management, 11, 198–226, 2021.
  • Oladapo, A.O., Olayiwola, M.O., Adedokun, K.A., Alaje, I.A., Adedeji, J.A., Kabiru, K.O., Optimal Control Analysis on Mathematical Model of Dynamical Transmission of Hiv-Malaria Co-Infection, Journal of Southwest Jiaotong University, 58, 124–148, 2023.
  • Oladapo, A.O., Olayiwola, M.O., Adedokun, K.A., Adedapo, A.I., Adedeji, J.A., Kabiru, K.O., et al., Mathematical Analysis of Sensitive Parameters on the Dynamical Transmission of HIV-Malaria Co-Infection, Jambura Journal of Biomathematics, 4, 37–45, 2023.
  • Bhandari, M., Rathnayake, I.U., Huygens, F., Genomic and Evolutionary insights into Asutralian Toxigenic Vibrio Cholerae 01 Strains, Microbiology Spectrum, 17, 20–27, 2024.
  • Hoefer, A., Pampaka, D., Herrera-Leon, S., Peiro, S., Varona, N., Molecular and Epidemiological Characterization of Toxigenic and non-toxigenic Corynebacterium Diphtheriae, Corynebacterium Belfanti, Corynebacterium Rouxii, Tanzania journal of sciences, 59, 32–48, 2025.
  • Eftimie, R., Gillard, J.J., Cantrell, D.A., Mathematical Models for Immunology: Current State of the Art and Future Research Directions, Bulletin of Mathematical Biology, 78, 2091–2134, 2023.
  • Engerman, S., Sokolloff, K., Factor Endowments, Inequality, and Paths of Development among New World Economics, Ethiopia Journal of Computational and Vatural Sciences, 3, 234–256, 2025.
  • Feldman W.E., Relation of Concentrations of Bacteria and Bacterial Antigen in Cerebrospinal Fluid to Prognosis in Patients with Bacterial Meningitis, National England Journal of Medicine; 29, 433–35, 2023.
  • Fing, C.H., Fitter, D.L., Borse, R.H., Meltzer, M.I., Tappero, J.W., Modeling the Effect of Water, Sanitation, and Hygiene and Oral Cholera Vaccine Implementation in Haiti, American Journal of Tropical Medicine and Hygiene, 89, 633–640, 2024.
  • Hanney, S.R., Gonzalez-Block, M.A., Buxton, M.J., Kogan, M., The Utilisation of Health Research in Policy-Making Concepts, Examples and Methods of Assessment, Health Research Policy and Systems, 1, 23–38, 2023.
  • Mojtaba, M.E., Adam, S.O., A Mathematical Model for Meningitis Disease, Red Sea University Journal of Basic and Applied Science, 2, 467– 472, 2024.
  • Asamoah, J.K., Nyabadza, F., Seidu, B., Chand, B., Dutta, H., Mathematical Modeling of Bacterial Meningitis Transmission Dynamics with Control Measures, Computational and Mathematical Methods in Medicine, 2, 29-41, 2023.
  • Audrey, S., Abel, J., Blazeby, J.M., Falk, S., Campbell, R., What Oncologists tell Patients about Survival Benefits of Palliative Chemotherapy and Implications for Informed Consent: Qualitative Study, Bio-Medical Journal of Sciences, 3, 182–105, 2024.
  • Azman, A.S., Lessler, J., Reactive Vaccination in the Presence of Disease Hotspots, Proceedings of the Royal Society of Biological Sciences, 282, 20–38, 2024.
  • Baleanu, D., Aydogan, M., Mohammadi, H., Rezapour, S., On Modeling of Epidemic Childhood Diseases with the Caputo-Fabrizio Derivative by using the Laplace Adomian Decomposition Method, Alexandria Engineering Journal, 59, 3029–3039, 2023.
  • Agrawal, R., Murmu, J., Kanungo, S., Pati, S., Nigeria on Alert: Diphtheria Outbreaks Require Urgent Action - A Critical Look at the Current Situation and Potential Solutions, New Microbes and New Infections, 52, 10–27, 2023.
  • Akra-Ismail, M., Makki, R.F., Chmaisse, H.N., Kazma, A., Zgheib, N.K., Association between Angiotensin-Converting Enzyme Insertion/Deletion Genetic Polymorphism and Hypertension in a Sample of Lebanese Patients, Genetic Testing and Molecular Biomarkers, 14, 787–792, 2024.
  • Ahmed, J., Halvorson, G.W., Gates, J.R., Measles-like Disease and Measles Antibody Titers in an Adult Population. Military Medicine, 144, 672–676, 2024.
  • Aniji, K., Chiu, Y.L., Wilkin, T., Measles, Mumps, and Rubella Serostatus and Response to MMR Vaccination among HIV-Infected Adults, AIDS Patient Care and STDs, 29, 461–464, 2024.
  • Asaboyi, J.L., Nashair, B.S., Bashaei, M.K., Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), JAMA, 19, 86–97, 2024.
  • Biggins, S.W., Angeli, P., Garcia‐Tsao, G., Ginès, P., Ling, S.C., Diagnosis, Evaluation and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome, American Journal of Bio-Mathematics, 34, 29–40, 2024.
  • Celen, O., Factors Influencing Outcome of surgery for primary Aldosteronism, Archives of Surgery, 6, 64–76, 2024.
  • John, F., Castillo, C., Feng, Z., Huang, W., On the computation of basic reproduction number and its role in global stability in mathematical approaches for emerging and reemerging infectious diseases, Decision Analytics, 25, 229–250, 2023.

Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission

Year 2025, Volume: 15 Issue: 1, 98 - 127, 01.07.2025
https://doi.org/10.37094/adyujsci.1578202

Abstract

This study presents a mathematical analysis of the SVEITR model, which incorporates susceptible, vaccinated, exposed, infected, treatment, and recovered populations to evaluate the dynamics of cholera spread. By integrating treatment and vaccination rates into the model, we aim to understand their impact on disease transmission and immunity. Our findings reveal that combining rapid treatment and vaccination significantly reduces the spread of cholera, highlighting the importance of these interventions in public health strategies. The model demonstrates that timely and widespread implementation of vaccination and treatment can effectively control outbreaks and mitigate the disease's impact. Through a numerical simulation of Laplace decomposition method the result reveal that treatment rate reduces the emanation of the disease and vaccination plays a vital role in curbing aftermath effect of wide-spread of the disease. Hence, the need for robust healthcare policies that prioritize these measures to achieve substantial progress in managing and eventually eradicating cholera, particularly in vulnerable regions. The SVEITR model provides a valuable framework for policymakers and healthcare professionals to devise efficient strategies for cholera control, contributing to improved public health outcomes

Supporting Institution

Osun State University, Osogbo

Thanks

Thank you.

References

  • Babalola, O.O, Adebisi, A.F, Odeyemi, K.A., Numerical Solution for Linear Integro-Differential Equations using Shifted Legendre Basis Functions, Jurnal Diferensial, Indonesia, 7, 55–72, 2025.
  • Olaosebikan, M.L., Kolawole, M.K., Bashiru, K.A., Transmission Dynamics of Tuberculosis Model with Control Strategies, Jambura Journal of Biomathematics, 4(2), 110–118, 2023.
  • Dere Z.O, Oladapo, A.O., Mathematical (Seirb) Model Analysis for Evaluating Cholera Control Strategies in Remote Dry Season Region, Jurnal Diferensial, 6, 142–169, 2024.
  • Harpring, R., Maghsoudi, A., Fikar, C., Piotrowicz, W.D., An Analysis of compounding factors of Epidemics in Complex Emergencies: a System Dynamics Approach, Journal of Humanitarian Logistics and Supply Chain Management, 11, 198–226, 2021.
  • Oladapo, A.O., Olayiwola, M.O., Adedokun, K.A., Alaje, I.A., Adedeji, J.A., Kabiru, K.O., Optimal Control Analysis on Mathematical Model of Dynamical Transmission of Hiv-Malaria Co-Infection, Journal of Southwest Jiaotong University, 58, 124–148, 2023.
  • Oladapo, A.O., Olayiwola, M.O., Adedokun, K.A., Adedapo, A.I., Adedeji, J.A., Kabiru, K.O., et al., Mathematical Analysis of Sensitive Parameters on the Dynamical Transmission of HIV-Malaria Co-Infection, Jambura Journal of Biomathematics, 4, 37–45, 2023.
  • Bhandari, M., Rathnayake, I.U., Huygens, F., Genomic and Evolutionary insights into Asutralian Toxigenic Vibrio Cholerae 01 Strains, Microbiology Spectrum, 17, 20–27, 2024.
  • Hoefer, A., Pampaka, D., Herrera-Leon, S., Peiro, S., Varona, N., Molecular and Epidemiological Characterization of Toxigenic and non-toxigenic Corynebacterium Diphtheriae, Corynebacterium Belfanti, Corynebacterium Rouxii, Tanzania journal of sciences, 59, 32–48, 2025.
  • Eftimie, R., Gillard, J.J., Cantrell, D.A., Mathematical Models for Immunology: Current State of the Art and Future Research Directions, Bulletin of Mathematical Biology, 78, 2091–2134, 2023.
  • Engerman, S., Sokolloff, K., Factor Endowments, Inequality, and Paths of Development among New World Economics, Ethiopia Journal of Computational and Vatural Sciences, 3, 234–256, 2025.
  • Feldman W.E., Relation of Concentrations of Bacteria and Bacterial Antigen in Cerebrospinal Fluid to Prognosis in Patients with Bacterial Meningitis, National England Journal of Medicine; 29, 433–35, 2023.
  • Fing, C.H., Fitter, D.L., Borse, R.H., Meltzer, M.I., Tappero, J.W., Modeling the Effect of Water, Sanitation, and Hygiene and Oral Cholera Vaccine Implementation in Haiti, American Journal of Tropical Medicine and Hygiene, 89, 633–640, 2024.
  • Hanney, S.R., Gonzalez-Block, M.A., Buxton, M.J., Kogan, M., The Utilisation of Health Research in Policy-Making Concepts, Examples and Methods of Assessment, Health Research Policy and Systems, 1, 23–38, 2023.
  • Mojtaba, M.E., Adam, S.O., A Mathematical Model for Meningitis Disease, Red Sea University Journal of Basic and Applied Science, 2, 467– 472, 2024.
  • Asamoah, J.K., Nyabadza, F., Seidu, B., Chand, B., Dutta, H., Mathematical Modeling of Bacterial Meningitis Transmission Dynamics with Control Measures, Computational and Mathematical Methods in Medicine, 2, 29-41, 2023.
  • Audrey, S., Abel, J., Blazeby, J.M., Falk, S., Campbell, R., What Oncologists tell Patients about Survival Benefits of Palliative Chemotherapy and Implications for Informed Consent: Qualitative Study, Bio-Medical Journal of Sciences, 3, 182–105, 2024.
  • Azman, A.S., Lessler, J., Reactive Vaccination in the Presence of Disease Hotspots, Proceedings of the Royal Society of Biological Sciences, 282, 20–38, 2024.
  • Baleanu, D., Aydogan, M., Mohammadi, H., Rezapour, S., On Modeling of Epidemic Childhood Diseases with the Caputo-Fabrizio Derivative by using the Laplace Adomian Decomposition Method, Alexandria Engineering Journal, 59, 3029–3039, 2023.
  • Agrawal, R., Murmu, J., Kanungo, S., Pati, S., Nigeria on Alert: Diphtheria Outbreaks Require Urgent Action - A Critical Look at the Current Situation and Potential Solutions, New Microbes and New Infections, 52, 10–27, 2023.
  • Akra-Ismail, M., Makki, R.F., Chmaisse, H.N., Kazma, A., Zgheib, N.K., Association between Angiotensin-Converting Enzyme Insertion/Deletion Genetic Polymorphism and Hypertension in a Sample of Lebanese Patients, Genetic Testing and Molecular Biomarkers, 14, 787–792, 2024.
  • Ahmed, J., Halvorson, G.W., Gates, J.R., Measles-like Disease and Measles Antibody Titers in an Adult Population. Military Medicine, 144, 672–676, 2024.
  • Aniji, K., Chiu, Y.L., Wilkin, T., Measles, Mumps, and Rubella Serostatus and Response to MMR Vaccination among HIV-Infected Adults, AIDS Patient Care and STDs, 29, 461–464, 2024.
  • Asaboyi, J.L., Nashair, B.S., Bashaei, M.K., Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), JAMA, 19, 86–97, 2024.
  • Biggins, S.W., Angeli, P., Garcia‐Tsao, G., Ginès, P., Ling, S.C., Diagnosis, Evaluation and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome, American Journal of Bio-Mathematics, 34, 29–40, 2024.
  • Celen, O., Factors Influencing Outcome of surgery for primary Aldosteronism, Archives of Surgery, 6, 64–76, 2024.
  • John, F., Castillo, C., Feng, Z., Huang, W., On the computation of basic reproduction number and its role in global stability in mathematical approaches for emerging and reemerging infectious diseases, Decision Analytics, 25, 229–250, 2023.
There are 26 citations in total.

Details

Primary Language English
Subjects Biological Mathematics
Journal Section Mathematics
Authors

Odeyemi Kazeem 0009-0008-0345-5664

Mutairu Kolawole 0000-0003-1500-2060

Publication Date July 1, 2025
Submission Date November 3, 2024
Acceptance Date June 3, 2025
Published in Issue Year 2025 Volume: 15 Issue: 1

Cite

APA Kazeem, O., & Kolawole, M. (2025). Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission. Adıyaman University Journal of Science, 15(1), 98-127. https://doi.org/10.37094/adyujsci.1578202
AMA Kazeem O, Kolawole M. Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission. ADYU J SCI. July 2025;15(1):98-127. doi:10.37094/adyujsci.1578202
Chicago Kazeem, Odeyemi, and Mutairu Kolawole. “Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission”. Adıyaman University Journal of Science 15, no. 1 (July 2025): 98-127. https://doi.org/10.37094/adyujsci.1578202.
EndNote Kazeem O, Kolawole M (July 1, 2025) Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission. Adıyaman University Journal of Science 15 1 98–127.
IEEE O. Kazeem and M. Kolawole, “Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission”, ADYU J SCI, vol. 15, no. 1, pp. 98–127, 2025, doi: 10.37094/adyujsci.1578202.
ISNAD Kazeem, Odeyemi - Kolawole, Mutairu. “Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission”. Adıyaman University Journal of Science 15/1 (July2025), 98-127. https://doi.org/10.37094/adyujsci.1578202.
JAMA Kazeem O, Kolawole M. Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission. ADYU J SCI. 2025;15:98–127.
MLA Kazeem, Odeyemi and Mutairu Kolawole. “Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission”. Adıyaman University Journal of Science, vol. 15, no. 1, 2025, pp. 98-127, doi:10.37094/adyujsci.1578202.
Vancouver Kazeem O, Kolawole M. Quantitative Modeling of Treatment and Vaccination Effects on the Dynamics of Cholera Transmission. ADYU J SCI. 2025;15(1):98-127.

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